Publications by authors named "Raymond W Colburn"

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Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Ca 2.2) blockers for the treatment of pain.
Mark J Wall, Nalin L Subasinghe, Michael P Winters, Mary Lou Lubin, Michael F A Finley, Raymond W Colburn

Bioorg Med Chem Lett· December 2018

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The antibody rHIgM22 facilitates hippocampal remyelination and ameliorates memory deficits in the cuprizone mouse model of demyelination.
Charlene Cui, Jing Wang, Ariana P Mullin, Anthony O Caggiano, Tom J Parry, Raymond W Colburn

Brain Res· September 2018

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rHIgM22 enhances remyelination in the brain of the cuprizone mouse model of demyelination.
Ariana P Mullin, Charlene Cui, Yu Wang, Jing Wang, Erika Troy, Raymond W Colburn

Neurobiol Dis· September 2017

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AC105 Increases Extracellular Magnesium Delivery and Reduces Excitotoxic Glutamate Exposure within Injured Spinal Cords in Rats.
Zhihong Huang, Zoran Filipovic, Nandakumar Mp, Chia Ung, Erika L Troy, Raymond W Colburn

J Neurotrauma· February 2017

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Recovery of sensorimotor function following sciatic nerve injury across multiple rat strains.
Anindita Ganguly, Corissa McEwen, Erika L Troy, Raymond W Colburn, Anthony O Caggiano

J Neurosci Methods· January 2017

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Large animal and primate models of spinal cord injury for the testing of novel therapies.
Brian K Kwon, Femke Streijger, Caitlin E Hill, Aileen J Anderson, Mark Bacon, Raymond W Colburn

Exp Neurol· July 2015

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Arylglycine derivatives as potent transient receptor potential melastatin 8 (TRPM8) antagonists.
Bin Zhu, Mingde Xia, Xiaoqing Xu, Donald W Ludovici, Manomi Tennakoon, Raymond W Colburn

Bioorg Med Chem Lett· April 2013

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A novel series of pyrazolylpiperidine N-type calcium channel blockers.
Nalin L Subasinghe, Mark J Wall, Michael P Winters, Ning Qin, Mary Lou Lubin, Raymond W Colburn

Bioorg Med Chem Lett· June 2012

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The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
Jay M Matthews, Ning Qin, Raymond W Colburn, Scott L Dax, Mike Hawkins

Bioorg Med Chem Lett· April 2012

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Discovery of vinylcycloalkyl-substituted benzimidazole TRPM8 antagonists effective in the treatment of cold allodynia.
Raul R Calvo, Sanath K Meegalla, Daniel J Parks, William H Parsons, Shelley K Ballentine, Raymond W Colburn

Bioorg Med Chem Lett· March 2012

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Design and optimization of benzimidazole-containing transient receptor potential melastatin 8 (TRPM8) antagonists.
Daniel J Parks, William H Parsons, Raymond W Colburn, Sanath K Meegalla, Shelley K Ballentine

J Med Chem· January 2011

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Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.
Ellen E Codd, Judith Baker, Michael R Brandt, Stewart Bryant, Chaozhong Cai, Raymond W Colburn

Toxicol Sci· October 2010

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Ex vivo delta opioid receptor autoradiography: CNS receptor occupancy of two novel compounds over their antihyperalgesic dose range.
Ellen E Codd, Jianya Ma, Sui-Po Zhang, Dennis J Stone, Raymond W Colburn

Pharmacol Biochem Behav· August 2010

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JNJ-20788560 [9-(8-azabicyclo[3.2.1]oct-3-ylidene)-9H-xanthene-3-carboxylic acid diethylamide], a selective delta opioid receptor agonist, is a potent and efficacious antihyperalgesic agent that does not produce respiratory depression, pharmacologic tolerance, or physical dependence.
Ellen E Codd, John R Carson, Raymond W Colburn, Dennis J Stone, Christopher R Van Besien

J Pharmacol Exp Ther· April 2009

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Attenuated cold sensitivity in TRPM8 null mice.
Raymond W Colburn, Mary Lou Lubin, Dennis J Stone, Yan Wang, Danielle Lawrence

Neuron· May 2007

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Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine.
Yi Liu, Mary Lou Lubin, Tasha L Reitz, Yan Wang, Raymond W Colburn

Eur J Pharmacol· January 2006

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Rationale, design, and synthesis of novel phenyl imidazoles as opioid receptor agonists for gastrointestinal disorders.
Henry J Breslin, Tamara A Miskowski, Bryan M Rafferty, Santosh V Coutinho, Jeffrey M Palmer, Raymond W Colburn

J Med Chem· October 2004

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Characterization of a neuropathic pain model: sciatic cryoneurolysis in the rat.
Joyce A DeLeo, Dennis W Coombs, Stan Willenbring, Raymond W Colburn, Christian Fromm

Pain· January 1994

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