Publications by authors named "John Rumsey"

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An induced pluripotent stem cell-derived NMJ platform for study of the NGLY1-Congenital Disorder of Deglycosylation.
Trevor Sasserath, Ashley L Robertson, Roxana Mendez, Tristan T Hays, Ethan Smith, John W Rumsey

Adv Ther (Weinh)· November 2022

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Classical Complement Pathway Inhibition in a "Human-On-A-Chip" Model of Autoimmune Demyelinating Neuropathies.
John W Rumsey, Case Lorance, Max Jackson, Trevor Sasserath, Christopher W McAleer

Adv Ther (Weinh)· June 2022

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A functional hiPSC-cortical neuron differentiation and maturation model and its application to neurological disorders.
Kaveena Autar, Xiufang Guo, John W Rumsey, Christopher J Long, Nesar Akanda

Stem Cell Reports· January 2022

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A Functional Human-on-a-Chip Autoimmune Disease Model of Myasthenia Gravis for Development of Therapeutics.
Virginia M Smith, Huan Nguyen, John W Rumsey, Christopher J Long, Michael L Shuler

Front Cell Dev Biol· November 2021

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Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation.
Victoria L Slaughter, John W Rumsey, Rachel Boone, Duaa Malik, Yunqing Cai

Sci Rep· June 2021

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Myelination and Node of Ranvier Formation in a Human Motoneuron-Schwann Cell Serum-Free Coculture.
Aakash Patel, John W Rumsey, Case Lorance, Christopher J Long, Briana Lee

ACS Chem Neurosci· September 2020

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Functional skeletal muscle model derived from SOD1-mutant ALS patient iPSCs recapitulates hallmarks of disease progression.
Agnes Badu-Mensah, Xiufang Guo, Christopher W McAleer, John W Rumsey, James J Hickman

Sci Rep· August 2020

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Differential Monocyte Actuation in a Three-Organ Functional Innate Immune System-on-a-Chip.
Trevor Sasserath, John W Rumsey, Christopher W McAleer, Lee Richard Bridges, Christopher J Long

Adv Sci (Weinh)· July 2020

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A human induced pluripotent stem cell-derived cortical neuron human-on-a chip system to study Aβ and tau-induced pathophysiological effects on long-term potentiation.
Julbert Caneus, Nesar Akanda, John W Rumsey, Xiufang Guo, Max Jackson

Alzheimers Dement (N Y)· May 2020

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A human-on-a-chip approach to tackling rare diseases.
Camilly P Pires de Mello, John Rumsey, Victoria Slaughter, James J Hickman

Drug Discov Today· November 2019

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Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics.
Christopher W McAleer, Christopher J Long, Daniel Elbrecht, Trevor Sasserath, L Richard Bridges, John W Rumsey

Sci Transl Med· June 2019

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Skeletal muscle PGC-1β signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice.
Samuel Lee, Teresa C Leone, Lisa Rogosa, John Rumsey, Julio Ayala

Am J Physiol Endocrinol Metab· May 2017

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Functional myotube formation from adult rat satellite cells in a defined serum-free system.
Christopher W McAleer, John W Rumsey, Maria Stancescu, James J Hickman

Biotechnol Prog· May 2016

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Myelination and node of Ranvier formation on sensory neurons in a defined in vitro system.
John W Rumsey, Christopher McAleer, Mainak Das, Abhijeet Bhalkikar, Kerry Wilson

In Vitro Cell Dev Biol Anim· September 2013

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Nuclear receptor/microRNA circuitry links muscle fiber type to energy metabolism.
Zhenji Gan, John Rumsey, Bethany C Hazen, Ling Lai, Teresa C Leone

J Clin Invest· June 2013

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Direct patterning of coplanar polyethylene glycol alkylsilane monolayers by deep-ultraviolet photolithography as a general method for high fidelity, long-term cell patterning and culture.
Kerry Wilson, Maria Stancescu, Mainak Das, John Rumsey, James Hickman

J Vac Sci Technol B Nanotechnol Microelectron· March 2011

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Neuromuscular junction formation between human stem-cell-derived motoneurons and rat skeletal muscle in a defined system.
Xiufang Guo, Mainak Das, John Rumsey, Mercedes Gonzalez, Maria Stancescu

Tissue Eng Part C Methods· December 2010

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Total skeletal muscle PGC-1 deficiency uncouples mitochondrial derangements from fiber type determination and insulin sensitivity.
Christoph Zechner, Ling Lai, Juliet F Zechner, Tuoyu Geng, Zhen Yan, John W Rumsey

Cell Metab· December 2010

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Tissue engineering the mechanosensory circuit of the stretch reflex arc: sensory neuron innervation of intrafusal muscle fibers.
John W Rumsey, Mainak Das, Abhijeet Bhalkikar, Maria Stancescu, James J Hickman

Biomaterials· November 2010

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A defined long-term in vitro tissue engineered model of neuromuscular junctions.
Mainak Das, John W Rumsey, Neelima Bhargava, Maria Stancescu, James J Hickman

Biomaterials· June 2010

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Developing a novel serum-free cell culture model of skeletal muscle differentiation by systematically studying the role of different growth factors in myotube formation.
Mainak Das, John W Rumsey, Neelima Bhargava, Cassie Gregory, Lisa Reidel

In Vitro Cell Dev Biol Anim· November 2009

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Skeletal muscle tissue engineering: a maturation model promoting long-term survival of myotubes, structural development of the excitation-contraction coupling apparatus and neonatal myosin heavy chain expression.
Mainak Das, John W Rumsey, Neelima Bhargava, Maria Stancescu, James J Hickman

Biomaterials· October 2009

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Node of Ranvier formation on motoneurons in vitro.
John W Rumsey, Mainak Das, Maria Stancescu, Marga Bott, Cristina Fernandez-Valle

Biomaterials· July 2009

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Electrophysiological and immunocytochemical characterization of DRG neurons on an organosilane surface in serum-free medium.
Jie Liu, John W Rumsey, Mainak Das, Peter Molnar, Cassie Gregory

In Vitro Cell Dev Biol Anim· September 2008

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Tissue engineering intrafusal fibers: dose- and time-dependent differentiation of nuclear bag fibers in a defined in vitro system using neuregulin 1-beta-1.
John W Rumsey, Mainak Das, Jung-Fong Kang, Robert Wagner, Peter Molnar

Biomaterials· March 2008

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