Publications by authors named "John Shryock"

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Protein kinase C and Ca(2+) -calmodulin-dependent protein kinase II mediate the enlarged reverse INCX induced by ouabain-increased late sodium current in rabbit ventricular myocytes.
Ying Wu, Leilei Wang, Jihua Ma, Yejia Song, Peihua Zhang, John C Shryock

Exp Physiol· April 2015

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Cardiac late Na⁺ current: proarrhythmic effects, roles in long QT syndromes, and pathological relationship to CaMKII and oxidative stress.
Luiz Belardinelli, Wayne R Giles, Sridharan Rajamani, Hrayr S Karagueuzian, John C Shryock

Heart Rhythm· February 2015

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Intracellular Na+ overload causes oxidation of CaMKII and leads to Ca2+ mishandling in isolated ventricular myocytes.
Serge Viatchenko-Karpinski, Dmytro Kornyeyev, Nesrine El-Bizri, Grant Budas, Peidong Fan, John C Shryock

J Mol Cell Cardiol· November 2014

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Ranolazine attenuates hypoxia- and hydrogen peroxide-induced increases in sodium channel late openings in ventricular myocytes.
Jihua Ma, Yejia Song, John C Shryock, Liangkun Hu, Weiping Wang

J Cardiovasc Pharmacol· July 2014

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The role of late I Na in development of cardiac arrhythmias.
Charles Antzelevitch, Vladislav Nesterenko, John C Shryock, Sridharan Rajamani, Yejia Song

Handb Exp Pharmacol· July 2014

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Larger late sodium current density as well as greater sensitivities to ATX II and ranolazine in rabbit left atrial than left ventricular myocytes.
Antao Luo, Jihua Ma, Yejia Song, Chunping Qian, Ying Wu, John C Shryock

Am J Physiol Heart Circ Physiol· February 2014

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Inhibition of the late sodium current slows t-tubule disruption during the progression of hypertensive heart disease in the rat.
Gary L Aistrup, Deepak K Gupta, James E Kelly, Matthew J O'Toole, Amanda Nahhas, John C Shryock

Am J Physiol Heart Circ Physiol· October 2013

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The arrhythmogenic consequences of increasing late INa in the cardiomyocyte.
John C Shryock, Yejia Song, Sridharan Rajamani, Charles Antzelevitch, Luiz Belardinelli

Cardiovasc Res· September 2013

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A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias.
Luiz Belardinelli, Gongxin Liu, Cathy Smith-Maxwell, Wei-Qun Wang, Nesrine El-Bizri, John C Shryock

J Pharmacol Exp Ther· January 2013

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Inhibition of apoptosis signal-regulating kinase 1 reduces myocardial ischemia-reperfusion injury in the mouse.
Stefano Toldo, David G Breckenridge, Eleonora Mezzaroma, Benjamin W Van Tassell, John Shryock

J Am Heart Assoc· October 2012

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An apoptosis signal-regulating kinase 1 inhibitor reduces cardiomyocyte apoptosis and infarct size in a rat ischemia-reperfusion model.
Paul Z Gerczuk, David G Breckenridge, John T Liles, Grant R Budas, John C Shryock

J Cardiovasc Pharmacol· September 2012

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Block of Na+ currents and suppression of action potentials in embryonic rat dorsal root ganglion neurons by ranolazine.
Ryoko Hirakawa, Nesrine El-Bizri, John C Shryock, Luiz Belardinelli, Sridharan Rajamani

Neuropharmacology· June 2012

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Calmodulin kinase II and protein kinase C mediate the effect of increased intracellular calcium to augment late sodium current in rabbit ventricular myocytes.
Jihua Ma, Antao Luo, Lin Wu, Wei Wan, Peihua Zhang, John C Shryock

Am J Physiol Cell Physiol· April 2012

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Ambrisentan and tadalafil synergistically relax endothelin-induced contraction of rat pulmonary arteries.
Faquan Liang, Suya Yang, Lina Yao, Luiz Belardinelli, John Shryock

Hypertension· March 2012

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Selective action of metoprolol to attenuate regadenoson-induced tachycardia in conscious dogs.
Gong Zhao, Suhua Zhang, John C Shryock, Xiaobin Xu, Manuel Ochoa

J Nucl Cardiol· February 2012

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Structure-activity relationships of 2-amino-3-aroyl-4-[(4-arylpiperazin-1-yl)methyl]thiophenes. Part 2: Probing the influence of diverse substituents at the phenyl of the arylpiperazine moiety on allosteric enhancer activity at the A₁ adenosine receptor.
Romeo Romagnoli, Pier Giovanni Baraldi, Maria Dora Carrion, Carlota Lopez Cara, Olga Cruz-Lopez, John C Shryock

Bioorg Med Chem· January 2012

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Nav1.5-dependent persistent Na+ influx activates CaMKII in rat ventricular myocytes and N1325S mice.
Lina Yao, Peidong Fan, Zhan Jiang, Serge Viatchenko-Karpinski, Yuzhi Wu, John C Shryock

Am J Physiol Cell Physiol· September 2011

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Antiadrenergic and hemodynamic effects of ranolazine in conscious dogs.
Gong Zhao, Erin Walsh, John C Shryock, Eric Messina, Yuzhi Wu

J Cardiovasc Pharmacol· June 2011

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Reducing the late sodium current improves cardiac function during sodium pump inhibition by ouabain.
Kirsten Hoyer, Yejia Song, Desuo Wang, Dillon Phan, James Balschi, John C Shryock

J Pharmacol Exp Ther· May 2011

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Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.
Lin Wu, Jihua Ma, Hong Li, Chao Wang, Eleonora Grandi, John C Shryock

Circulation· April 2011

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Inhibition of aldehyde dehydrogenase-2 suppresses cocaine seeking by generating THP, a cocaine use-dependent inhibitor of dopamine synthesis.
Lina Yao, Peidong Fan, Maria Arolfo, Zhan Jiang, M Foster Olive, John Shryock

Nat Med· September 2010

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Sulfonylureas uncouple glucose-dependence for GPR40-mediated enhancement of insulin secretion from INS-1E cells.
Ming Yang, Jeffrey W Chisholm, Sandriyana Soelaiman, John C Shryock

Mol Cell Endocrinol· February 2010

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Abnormal left ventricular relaxation in patients with long QT syndrome.
Luiz Belardinelli, Arvinder Dhalla, John Shryock

Eur Heart J· November 2009

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Use-dependent block of cardiac late Na(+) current by ranolazine.
Sridharan Rajamani, Nesrine El-Bizri, John C Shryock, Jonathan C Makielski, Luiz Belardinelli

Heart Rhythm· November 2009

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Ranolazine as a cardioplegia additive improves recovery of diastolic function in isolated rat hearts.
Hyosook Hwang, Joseph M Arcidi, Sharon L Hale, Boris Z Simkhovich, Luiz Belardinelli, John C Shryock

Circulation· September 2009

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