Publications by authors named "John Vierling"

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Chronic Liver Allograft Rejection: Histopathological Insights and Future Directions.
Samar Seeman, Joshua Wong, Adib Edilbi, Ashton A Connor, John M Vierling

Results Probl Cell Differ· January 2026

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Fracture events in patients with primary biliary cholangitis during treatment with seladelpar in the phase III RESPONSE trial.
John M Vierling, Gideon M Hirschfield, Robert P Kustra, Xiangyu Liu, Sarah Proehl

Hepatol Commun· December 2025

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Multiscale modeling of drug-induced liver injury from organ to lobule.
Alon Malka-Markovitz, Stelian Camara Dit Pinto, Mohammed Cherkaoui, Steven M Levine, Sharmila Anandasabapathy, John M Vierling

NPJ Digit Med· June 2025

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Long-Term Efficacy and Safety of Selective PPARδ Agonist Seladelpar in Primary Biliary Cholangitis: ASSURE Interim Study Results.
Cynthia Levy, Palak J Trivedi, Kris V Kowdley, Stuart C Gordon, Christopher L Bowlus, John M Vierling

Am J Gastroenterol· June 2025

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Statin Use Is Associated With Protection Against Acute Cholangitis in Patients With Primary Sclerosing Cholangitis: A Multicenter Retrospective Cohort Study.
Chiraag Kulkarni, George Cholankeril, Touran Fardeen, Joseph Rathkey, Samir Khan, John Vierling

Clin Transl Gastroenterol· April 2025

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Lessons From COBALT: Will the Bell Also Toll for Thee?
John Moore Vierling, Paul J Pockros

Am J Gastroenterol· February 2025

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A virtual scalable model of the Hepatic Lobule for acetaminophen hepatotoxicity prediction.
Stelian Camara Dit Pinto, Jalal Cherkaoui, Debarshi Ghosh, Valentine Cazaubon, Kenza E Benzeroual, John M Vierling

NPJ Digit Med· November 2024

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Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA).
Virginia C Clark, Charlie Strange, Pavel Strnad, Antonio J Sanchez, Paul Kwo, John M Vierling

Gastroenterology· October 2024

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Primary biliary cholangitis.
Atsushi Tanaka, Xiong Ma, Atsushi Takahashi, John M Vierling

Lancet· September 2024

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Metabolomics biomarkers of hepatocellular carcinoma in a prospective cohort of patients with cirrhosis.
Jessica I Sanchez, Antoine C Fontillas, Suet-Ying Kwan, Caren I Sanchez, Tiffany L Calderone, John M Vierling

JHEP Rep· August 2024

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Immunopathogenesis of Primary Biliary Cholangitis, Primary Sclerosing Cholangitis and Autoimmune Hepatitis: Themes and Concepts.
Palak J Trivedi, Gideon M Hirschfield, David H Adams, John M Vierling

Gastroenterology· June 2024

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Consensus Guidelines: Best Practices for the Prevention, Detection and Management of Hepatitis B Virus Reactivation in Clinical Trials with Immunosuppressive/Immunomodulatory Therapy.
Eric B Cohen, Arie Regev, Anju Garg, Adrian M Di Bisceglie, James H Lewis, John M Vierling

Drug Saf· April 2024

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The clinical imperative of a complete biochemical response to immunosuppression in autoimmune hepatitis: Close is not good enough!
George Cholankeril, John M Vierling

Hepatology· March 2024

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Autoimmune hepatitis: Brighton Collaboration case definition and guidelines for data collection, analysis, and presentation of immunisation safety data.
Sonali Kochhar, David N Assis, Cara Mack, Hector S Izurieta, Luigi Muratori, John M Vierling

Vaccine· March 2024

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Efficacy and Safety of Elafibranor in Primary Biliary Cholangitis.
Kris V Kowdley, Christopher L Bowlus, Cynthia Levy, Ulus S Akarca, Mario Reis Alvares-da-Silva, John M Vierling

N Engl J Med· February 2024

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A Phase 3 Trial of Seladelpar in Primary Biliary Cholangitis.
Gideon M Hirschfield, Christopher L Bowlus, Marlyn J Mayo, Andreas E Kremer, John M Vierling

N Engl J Med· February 2024

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Open-label, clinical trial extension: Two-year safety and efficacy results of seladelpar in patients with primary biliary cholangitis.
Marlyn J Mayo, John M Vierling, Christopher L Bowlus, Cynthia Levy, Gideon M Hirschfield

Aliment Pharmacol Ther· January 2024

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Editorial: The evolving paradigms and treatments for primary biliary cholangitis-Authors' reply.
Marlyn J Mayo, John M Vierling, Christopher L Bowlus

Aliment Pharmacol Ther· January 2024

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Rusfertide for the treatment of iron overload in HFE-related haemochromatosis: an open-label, multicentre, proof-of-concept phase 2 trial.
Kris V Kowdley, Nishit B Modi, Kevork Peltekian, John M Vierling, Christopher Ferris

Lancet Gastroenterol Hepatol· December 2023

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Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report.
Raúl J Andrade, Guruprasad P Aithal, Ynto S de Boer, Rodrigo Liberal, Alexander Gerbes, John M Vierling

J Hepatol· September 2023

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Seladelpar efficacy and safety at 3 months in patients with primary biliary cholangitis: ENHANCE, a phase 3, randomized, placebo-controlled study.
Gideon M Hirschfield, Mitchell L Shiffman, Aliya Gulamhusein, Kris V Kowdley, John M Vierling

Hepatology· August 2023

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Tropifexor for nonalcoholic steatohepatitis: an adaptive, randomized, placebo-controlled phase 2a/b trial.
Arun J Sanyal, Patricia Lopez, Eric J Lawitz, Kathryn J Lucas, Juergen Loeffler, John M Vierling

Nat Med· February 2023

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Prevalence and clinical significance of portal inflammation, portal plasma cells, interface hepatitis and biliary injury in liver biopsies from patients with non-alcoholic steatohepatitis.
Sadhna Dhingra, Juhi D Mahadik, Yaman Tarabishy, Sarah B May, John M Vierling

Pathology· October 2022

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Efficacy and Safety of a Botanical Formula Fuzheng Huayu for Hepatic Fibrosis in Patients with CHC: Results of a Phase 2 Clinical Trial.
Tarek Hassanein, Dean Tai, Chenghai Liu, Terry D Box, Myron J Tong, John M Vierling

Evid Based Complement Alternat Med· July 2022

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Single Topic Conference on Autoimmune Liver Disease from the Canadian Association for the Study of the Liver.
Aldo J Montano-Loza, Jessica R Allegretti, Angela Cheung, Maryam Ebadi, David Jones, John M Vierling

Can Liver J· November 2021

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