Publications by authors named "John Weldon"

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Intracellular trafficking of furin enhances cellular intoxication by recombinant immunotoxins based on Pseudomonas exotoxin A.
Brian D Grossman, Jack D Sanford, Yuyi Zhu, Cynthia B Zeller, John E Weldon

Biol Open· June 2025

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Faculty rewards from course-based undergraduate research experiences (CURE) in biochemistry.
Ana Maria Soto, John E Weldon, Stephen P Hancock

J Microbiol Biol Educ· April 2025

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A deep learning approach to case prioritisation of colorectal biopsies.
Ciara D White, Runjan Chetty, John Weldon, Maria E Morrissey, Rob Sykes

Histopathology· February 2025

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Characterization of the Structural Requirements for the NADase Activity of Bacterial Toll/IL-1R domains in a Course-based Undergraduate Research Experience.
Tamara Vallejo-Schmidt, Cheyenne Palm, Trinity Obiorah, Abra Rachida Koudjra, Katrina Schmidt, John E Weldon

Immunohorizons· August 2024

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Evaluating the influence of common antibiotics on the efficacy of a recombinant immunotoxin in tissue culture.
Yuyi Zhu, John E Weldon

BMC Res Notes· May 2019

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Investigation of amino acid specificity in the CydX small protein shows sequence plasticity at the functional level.
Jessica J Hobson, Austin S Gallegos, Benjamin W Atha, John P Kelly, Christina D Lein, John E Weldon

PLoS One· January 2019

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The Effects of Forced Exhalation and Inhalation, Grunting, and Valsalva Maneuver on Forehand Force in Collegiate Tennis Players.
Dennis G OʼConnell, Jacob F Brewer, Timothy H Man, John S Weldon, Martha R Hinman

J Strength Cond Res· February 2016

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Designing the furin-cleavable linker in recombinant immunotoxins based on Pseudomonas exotoxin A.
John E Weldon, Martin Skarzynski, Jamy A Therres, Joshua R Ostovitz, Hong Zhou

Bioconjug Chem· June 2015

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A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicity.
John E Weldon, Laiman Xiang, Jingli Zhang, Richard Beers, Dawn A Walker

Mol Cancer Ther· January 2013

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Identification and elimination of an immunodominant T-cell epitope in recombinant immunotoxins based on Pseudomonas exotoxin A.
Ronit Mazor, Aaron N Vassall, Jaime A Eberle, Richard Beers, John E Weldon

Proc Natl Acad Sci U S A· December 2012

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A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.
Wenhai Liu, Masanori Onda, Changhoon Kim, Laiman Xiang, John E Weldon

Protein Eng Des Sel· January 2012

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A guide to taming a toxin--recombinant immunotoxins constructed from Pseudomonas exotoxin A for the treatment of cancer.
John E Weldon, Ira Pastan

FEBS J· December 2011

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Immunotoxins with decreased immunogenicity and improved activity.
Ira Pastan, Masanori Onda, John Weldon, David Fitzgerald, Robert Kreitman

Leuk Lymphoma· June 2011

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Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.
Masanori Onda, Richard Beers, Laiman Xiang, Byungkook Lee, John E Weldon

Proc Natl Acad Sci U S A· April 2011

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A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.
Johanna K Hansen, John E Weldon, Laiman Xiang, Richard Beers, Masanori Onda

J Immunother· April 2010

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A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.
John E Weldon, Laiman Xiang, Oleg Chertov, Inger Margulies, Robert J Kreitman

Blood· April 2009

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Pigment epithelium-derived factor binds to hyaluronan. Mapping of a hyaluronan binding site.
S Patricia Becerra, L Alberto Perez-Mediavilla, John E Weldon, Silvia Locatelli-Hoops, Preenie Senanayake

J Biol Chem· November 2008

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Structure and properties of a truely apo form of AraC dimerization domain.
John E Weldon, Michael E Rodgers, Christopher Larkin, Robert F Schleif

Proteins· February 2007

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Specific interactions by the N-terminal arm inhibit self-association of the AraC dimerization domain.
John E Weldon, Robert F Schleif

Protein Sci· December 2006

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Glycosaminoglycans in human retinoblastoma cells: heparan sulfate, a modulator of the pigment epithelium-derived factor-receptor interactions.
Elena M Alberdi, John E Weldon, S Patricia Becerra

BMC Biochem· February 2003

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