Publications by authors named "John Whoriskey"

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Sequence-Based Viscosity Prediction for Rapid Antibody Engineering.
Bram Estes, Mani Jain, Lei Jia, John Whoriskey, Brian Bennett

Biomolecules· May 2024

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Development of an ICOSL and BAFF bispecific inhibitor AMG 570 for systemic lupus erythematosus treatment.
Ming Zhang, Francis Lee, Anna Knize, Frederick Jacobsen, Steven Yu, John Whoriskey

Clin Exp Rheumatol· December 2019

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Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways.
Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, John Whoriskey

Front Pharmacol· February 2019

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Discovery and in Vivo Evaluation of the Potent and Selective PI3Kδ Inhibitors 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-6-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-0687) and 2-((1S)-1-((6-Amino-5-cyano-4-pyrimidinyl)amino)ethyl)-5-fluoro-N-methyl-3-(2-pyridinyl)-4-quinolinecarboxamide (AM-1430).
Felix Gonzalez-Lopez de Turiso, Xiaolin Hao, Youngsook Shin, Minna Bui, Iain D G Campuzano, John Whoriskey

J Med Chem· August 2016

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Discovery, Optimization, and in Vivo Evaluation of Benzimidazole Derivatives AM-8508 and AM-9635 as Potent and Selective PI3Kδ Inhibitors.
Youngsook Shin, Julia Suchomel, Mario Cardozo, Jason Duquette, Xiao He, John Whoriskey

J Med Chem· January 2016

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Discovery and in vivo evaluation of (S)-N-(1-(7-fluoro-2-(pyridin-2-yl)quinolin-3-yl)ethyl)-9H-purin-6-amine (AMG319) and related PI3Kδ inhibitors for inflammation and autoimmune disease.
Timothy D Cushing, Xiaolin Hao, Youngsook Shin, Kristin Andrews, Matthew Brown, John Whoriskey

J Med Chem· January 2015

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G-protein-coupled receptor 35 is a target of the asthma drugs cromolyn disodium and nedocromil sodium.
Yuhua Yang, Jenny Ying-Lin Lu, Xiaosu Wu, Shamin Summer, John Whoriskey

Pharmacology· December 2010

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Spontaneous colitis occurrence in transgenic mice with altered B7-mediated costimulation.
Gisen Kim, Olga Turovskaya, Matthew Levin, Fergus R Byrne, John S Whoriskey

J Immunol· October 2008

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Potent activity of soluble B7RP-1-Fc in therapy of murine tumors in syngeneic hosts.
Gulshan Ara, Angelo Baher, Neal Storm, Tom Horan, Claudia Baikalov, John S Whoriskey

Int J Cancer· February 2003

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