Publications by authors named "John Wrangle"

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County-Level Cervical Cancer Screening Coverage and Differences in Incidence and Mortality.
Trisha L Amboree, Jane R Montealegre, Haluk Damgacioglu, Brian Orr, John Wrangle

JAMA Netw Open· August 2025

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Zipalertinib in Patients With Epidermal Growth Factor Receptor Exon 20 Insertion-Positive Non-Small Cell Lung Cancer Previously Treated With Platinum-Based Chemotherapy With or Without Amivantamab.
Zofia Piotrowska, Antonio Passaro, Danny Nguyen, Gerrina Ruiter, Ross A Soo, John Wrangle

J Clin Oncol· July 2025

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Dual targeting of tumoral cells and immune microenvironment by blocking the IL-33/IL1RL1 pathway.
Denggang Fu, Hua Jiang, Alan Long, Ella Harris, Hongfen Guo, John Wrangle

Nat Commun· July 2025

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IL-15: from discovery to FDA approval.
Zihai Li, John Wrangle, Kai He, Jonathan Sprent, Mark P Rubinstein

J Hematol Oncol· February 2025

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Safety, Tolerability, and Antitumor Activity of Zipalertinib Among Patients With Non-Small-Cell Lung Cancer Harboring Epidermal Growth Factor Receptor Exon 20 Insertions.
Zofia Piotrowska, Daniel Shao-Weng Tan, Egbert F Smit, Alexander I Spira, Ross A Soo, John M Wrangle

J Clin Oncol· September 2023

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Novel Collaborations Across Training Programs to Support Mentoring in Sex Differences Research.
Aimee L McRae-Clark, Kathleen T Brady, Diana Lee-Chavarria, Jacqueline F McGinty, Kevin M Gray, John Wrangle

J Womens Health (Larchmt)· August 2023

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Association of age with survival in older patients with cutaneous melanoma treated with immune checkpoint inhibitors.
Ashley V Howell, Mulugeta Gebregziabher, Bruce H Thiers, Evan M Graboyes, Chrystal M Paulos, John M Wrangle

J Geriatr Oncol· September 2022

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DNA-methylation for the detection and distinction of 19 human malignancies.
Ludmila Danilova, John Wrangle, James G Herman, Leslie Cope

Epigenetics· April 2022

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Phase I Trial Characterizing the Pharmacokinetic Profile of N-803, a Chimeric IL-15 Superagonist, in Healthy Volunteers.
Mark P Rubinstein, Cameron Williams, Caroline Mart, Jonathan Beall, Linda MacPherson, John Wrangle

J Immunol· March 2022

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Neoadjuvant presurgical PD-1 inhibition in oral cavity squamous cell carcinoma.
Hannah M Knochelmann, Joshua D Horton, Sixue Liu, Kent Armeson, John M Kaczmar, John M Wrangle

Cell Rep Med· October 2021

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A Phase 1-2 Study of Rovalpituzumab Tesirine in Combination With Nivolumab Plus or Minus Ipilimumab in Patients With Previously Treated Extensive-Stage SCLC.
Jyoti Malhotra, Petros Nikolinakos, Ticiana Leal, Jonathan Lehman, Daniel Morgensztern, John M Wrangle

J Thorac Oncol· September 2021

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Comparative analysis of antibodies to SARS-CoV-2 between asymptomatic and convalescent patients.
Connor J Dwyer, Colleen A Cloud, Cindy Wang, Philip Heidt, Paramita Chakraborty, John Wrangle

iScience· June 2021

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Immune checkpoint inhibitors retain effectiveness in older patients with cutaneous metastatic melanoma.
Ashley V Howell, Mulugeta Gebregziabher, Bruce H Thiers, Chrystal M Paulos, John M Wrangle

J Geriatr Oncol· April 2021

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Can We MIRror the Efficacy of Immune Checkpoints With miRNAs?
Mariam Alexander, John Wrangle

J Thorac Oncol· November 2020

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Epigenetic therapy inhibits metastases by disrupting premetastatic niches.
Zhihao Lu, Jianling Zou, Shuang Li, Michael J Topper, Yong Tao, John Wrangle

Nature· March 2020

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SLC36A1-mTORC1 signaling drives acquired resistance to CDK4/6 inhibitors.
Akihiro Yoshida, Yiwen Bu, Shuo Qie, John Wrangle, E Ramsay Camp

Sci Adv· September 2019

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Quantitative Spatial Profiling of PD-1/PD-L1 Interaction and HLA-DR/IDO-1 Predicts Improved Outcomes of Anti-PD-1 Therapies in Metastatic Melanoma.
Douglas B Johnson, Jennifer Bordeaux, Ju Young Kim, Christine Vaupel, David L Rimm, John M Wrangle

Clin Cancer Res· November 2018

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Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8 T Cells.
C Bryce Johnson, Bennett R May, Brian P Riesenberg, Samantha Suriano, Shikhar Mehrotra, John M Wrangle

Cancer Res· June 2018

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ALT-803, an IL-15 superagonist, in combination with nivolumab in patients with metastatic non-small cell lung cancer: a non-randomised, open-label, phase 1b trial.
John M Wrangle, Vamsidhar Velcheti, Manish R Patel, Elizabeth Garrett-Mayer, Elizabeth G Hill

Lancet Oncol· May 2018

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The clinical implications of immunogenomics in colorectal cancer: A path for precision medicine.
Jenny M Riley, Ashley W Cross, Chrystal M Paulos, Mark P Rubinstein, John Wrangle

Cancer· April 2018

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IL-2 and Beyond in Cancer Immunotherapy.
John M Wrangle, Alicia Patterson, C Bryce Johnson, Daniel J Neitzke, Shikhar Mehrotra

J Interferon Cytokine Res· February 2018

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Inducible Enhancement of T Cell Function and Anti-tumor Activity after Adoptive Transfer.
John Wrangle, Chrystal M Paulos, Thomas W Smith, Michael I Nishimura, Mark P Rubinstein

Mol Ther· September 2017

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Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
Daniel J Neitzke, Jacob S Bowers, Kristina Andrijauskaite, Nathaniel S O'Connell, Elizabeth Garrett-Mayer, John Wrangle

Cancer Immunol Immunother· June 2017

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First-Line Nivolumab in Stage IV or Recurrent Non-Small-Cell Lung Cancer.
David P Carbone, Martin Reck, Luis Paz-Ares, Benjamin Creelan, Leora Horn, John M Wrangle

N Engl J Med· June 2017

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β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.
Kinga Majchrzak, Michelle H Nelson, Jacob S Bowers, Stefanie R Bailey, Megan M Wyatt, John M Wrangle

JCI Insight· April 2017

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