Publications by authors named "Jonathan A Shortt"

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Enabling reproducible type 1 diabetes polygenic risk scoring for clinical and translational applications.
Maizy S Brasher, Matthew J Fisher, Carolina Sanchez Wild, Jonathan A Shortt, Krista Miller

medRxiv· July 2025

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Ancestry Calibration of Polygenic Risk Scores Improves Risk Stratification and Effect Estimation in African American Adults.
Luciana B Vargas, Mariah C Meyer, Iain R Konigsberg, Aastha Kakar, Patrick M Carry, Jonathan A Shortt

medRxiv· June 2025

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Pharmacogenomics of the Etonogestrel Contraceptive Implant: A Genome-Wide Association Study of Steady-State Etonogestrel Concentrations.
Aaron Lazorwitz, Christina L Aquilante, Jonathan A Shortt, Christopher R Gignoux, Stephanie Teal

O G Open· February 2025

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GenoSiS: A Biobank-Scale Genotype Similarity Search Architecture for Creating Dynamic Patient-Match Cohorts.
Kristen Schneider, Murad Chowdhury, Mariano Tepper, Jawad Khan, , Jonathan A Shortt

bioRxiv· November 2024

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Genomic Selection Signals in Andean Highlanders Reveal Adaptive Placental Metabolic Phenotypes That Are Disrupted in Preeclampsia.
Katie A O'Brien, Wanjun Gu, Julie A Houck, Lorenz M W Holzner, Hong Wa Yung, Jonathan A Shortt

Hypertension· February 2024

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Thyroid Cancer Polygenic Risk Score Improves Classification of Thyroid Nodules as Benign or Malignant.
Nikita Pozdeyev, Manjiri Dighe, Martin Barrio, Christopher Raeburn, Harry Smith, Jonathan A Shortt

J Clin Endocrinol Metab· January 2024

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Building a vertically integrated genomic learning health system: The biobank at the Colorado Center for Personalized Medicine.
Laura K Wiley, Jonathan A Shortt, Emily R Roberts, Jan Lowery, Elizabeth Kudron

Am J Hum Genet· January 2024

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Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies.
Colleen G Julian, Julie A Houck, Sahand Fallahi, Litzi Lazo-Vega, Christopher J Matarazzo, Jonathan A Shortt

Physiol Genomics· September 2023

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Disease risk and healthcare utilization among ancestrally diverse groups in the Los Angeles region.
Christa Caggiano, Arya Boudaie, Ruhollah Shemirani, Joel Mefford, Ella Petter, Jonathan A Shortt

Nat Med· July 2023

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COVID-19 Mortality in the Colorado Center for Personalized Medicine Biobank.
Amanda N Brice, Lauren A Vanderlinden, Katie M Marker, David Mayer, Meng Lin, Jonathan A Shortt

Int J Environ Res Public Health· January 2023

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Global Biobank Meta-analysis Initiative: Powering genetic discovery across human disease.
Wei Zhou, Masahiro Kanai, Kuan-Han H Wu, Humaira Rasheed, Kristin Tsuo, Jonathan A Shortt

Cell Genom· October 2022

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Applicability of ancestral genotyping in pharmacogenomic research with hormonal contraception.
Aaron Lazorwitz, Christina L Aquilante, Jonathan A Shortt, Jeanelle Sheeder, Stephanie Teal

Clin Transl Sci· September 2021

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Soluble CD14 Levels in the Jackson Heart Study: Associations With Cardiovascular Disease Risk and Genetic Variants.
Maggie A Stanislawski, Leslie A Lange, Laura M Raffield, Neil A Zakai, Mariah Meyer, Jonathan A Shortt

Arterioscler Thromb Vasc Biol· June 2021

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Adaptive Admixture of HLA Class I Allotypes Enhanced Genetically Determined Strength of Natural Killer Cells in East Asians.
Zhihui Deng, Jianxin Zhen, Genelle F Harrison, Guobin Zhang, Rui Chen, Jonathan A Shortt

Mol Biol Evol· May 2021

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Population genomic analyses of schistosome parasites highlight critical challenges facing endgame elimination efforts.
Jonathan A Shortt, Laura E Timm, Nicole R Hales, Zachary L Nikolakis, Drew R Schield

Sci Rep· March 2021

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Finding and extending ancient simple sequence repeat-derived regions in the human genome.
Jonathan A Shortt, Robert P Ruggiero, Corey Cox, Aaron C Wacholder, David D Pollock

Mob DNA· February 2020

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Squamate reptiles challenge paradigms of genomic repeat element evolution set by birds and mammals.
Giulia I M Pasquesi, Richard H Adams, Daren C Card, Drew R Schield, Andrew B Corbin, Jonathan A Shortt

Nat Commun· July 2018

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Whole Genome Amplification and Reduced-Representation Genome Sequencing of Schistosoma japonicum Miracidia.
Jonathan A Shortt, Daren C Card, Drew R Schield, Yang Liu, Bo Zhong

PLoS Negl Trop Dis· January 2017

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Platform technology to generate broadly cross-reactive antibodies to α-helical epitopes in hemagglutinin proteins from influenza A viruses.
Ziqing Jiang, Lajos Gera, Colin T Mant, Brooke Hirsch, Zhe Yan, Jonathan A Shortt

Biopolymers· March 2016

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