Publications by authors named "Jonathan Brody"

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The Role of Tumor-Intrinsic HuR in Modeling the Pancreatic Tumor Microenvironment: Molecular Mechanisms and Therapeutic Opportunities.
Katherine R Pelz, Kyle P Gribbin, Tess Sevetson, Jonathan R Brody

Mol Cell Biol· December 2025

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Challenges and caveats in manipulating extracellular vesicle secretion from pancreatic cancer cells.
Jennifer M Finan, Jonathan R Brody

Cancer Biol Ther· December 2025

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MicroCT Enables Simultaneous Longitudinal Tracking of Murine Pancreatic Cancer Progression and Cachexia.
Katherine R Pelz, Philip Jimenez, Colin J Daniel, Samuel D Newton, Melissa Cunningham, Jonathan R Brody

Cancer Res Commun· December 2025

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A window trial in metastatic pancreatic ductal adenocarcinoma reveals resistance mechanisms to targeting the KRAS-MEK pathway.
Motoyuki Tsuda, Dove Keith, Colin J Daniel, Carl Pelz, Katie E Blise, Jonathan R Brody

bioRxiv· December 2025

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The RNA-binding protein HuR impairs adipose tissue anabolism in pancreatic cancer cachexia.
Paige C Arneson-Wissink, Katherine Pelz, Beth Worley, Heike Mendez, Peter Pham, Jonathan R Brody

bioRxiv· September 2025

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HuR-Regulated Extracellular Vesicles Promote Endothelial Cell Remodeling in Pancreatic Cancer.
Jennifer M Finan, Yifei Guo, Alexandra Q Bartlett, Kevin Hawthorne, Matthew Reyer, Jonathan R Brody

Cancer Res Commun· September 2025

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Nuclear cGAS mediated replication stress and mitotic catastrophe can overcome gemcitabine resistance.
Soon Young Park, Kang Jin Jeong, Alfonso Poire, Bo Young Jeong, Yuhan Sheng, Jonathan R Brody

Cancer Lett· September 2025

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Myc and Kras cooperate in adult acinar cells to drive phenotypic heterogeneity, metastasis, and therapeutic resistance in a novel pancreatic cancer mouse model.
Isabel A English, Patrick J Worth, Kevin Alexander MacPherson-Hawthorne, Macarena Vergara, Katherine Pelz, Jonathan Brody

bioRxiv· July 2025

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MicroCT enables simultaneous longitudinal tracking of murine pancreatic cancer progression and cachexia.
Katherine R Pelz, Philip Jimenez, Colin J Daniel, Samuel D Newton, Melissa Cunningham, Jonathan R Brody

bioRxiv· June 2025

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Addressing Pancreatic Cancer Disparities in Oregon's Native American Population via Tribally Responsive Research Systems with The Confederated Tribes of Warm Springs.
Jared Delaney, Lonnie James, Paige Farris, Kaitlin Greene, Brett Sheppard, Jonathan Brody

Res Sq· June 2025

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Targeting BARD1 suppresses a Myc-dependent transcriptional program and tumor growth in pancreatic ductal adenocarcinoma.
Sohum Patel, Eleanor Jenkins, Rutuj P Kusurkar, Sherry Lee, Wei Jiang, Jonathan R Brody

Neoplasia· May 2025

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Post-transcriptional regulator HuR promotes immune evasion in pancreatic ductal adenocarcinoma.
Yifei Guo, Jennifer M Finan, Alexandra Q Bartlett, Shamilene Sivagnanam, Katie E Blise, Jonathan R Brody

bioRxiv· April 2025

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MYC Serine 62 phosphorylation promotes its binding to DNA double strand breaks to facilitate repair and cell survival under genotoxic stress.
Gabriel M Cohn, Colin J Daniel, Jennifer R Eng, Xiao-Xin Sun, Carl Pelz, Jonathan R Brody

bioRxiv· March 2025

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Corrigendum to "A Surgeon-Scientist's Pursuit of the Elusive R01" Volume 303, p. 461-467, November 2024.
Jordan M Winter, Jonathan R Brody

J Surg Res· February 2025

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Pancreatic cancer-intrinsic HuR regulates the pro-tumorigenic properties of extracellular vesicles.
Jennifer M Finan, Yifei Guo, Alexandra Q Bartlett, Matthew Reyer, Kevin Hawthorne, Jonathan R Brody

bioRxiv· February 2025

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Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer.
Jason M Link, Jennifer R Eng, Carl Pelz, Kevin MacPherson-Hawthorne, Patrick J Worth, Jonathan R Brody

Nat Cancer· January 2025

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The polymeric fluoropyrimidine CF10 overcomes limitations of 5-FU in pancreatic ductal adenocarcinoma cells through increased replication stress.
Jennifer M Finan, Roberto Di Niro, Soon Young Park, Kang Jin Jeong, Madeline D Hedberg, Jonathan R Brody

Cancer Biol Ther· December 2024

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Challenges and Opportunities in Targeting the Complex Pancreatic Tumor Microenvironment.
Jennifer M Finan, Yifei Guo, Shaun M Goodyear, Jonathan R Brody

JCO Oncol Adv· December 2024

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CASPER: A Phase I trial combining calaspargase pegol-mnkl and cobimetinib in pancreatic cancer.
Charles D Lopez, Adel Kardosh, Emerson Y Chen, Guillaume Pegna, Alexander Guimaraes, Jonathan R Brody

Future Oncol· November 2024

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A Surgeon-Scientist's Pursuit of the Elusive R01.
Jordan M Winter, Jonathan R Brody

J Surg Res· November 2024

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IDH1 Inhibition Potentiates Chemotherapy Efficacy in Pancreatic Cancer.
Mehrdad Zarei, Omid Hajihassani, Jonathan J Hue, Alexander W Loftus, Hallie J Graor, Jonathan R Brody

Cancer Res· September 2024

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The Pivotal Role of Germline BRCA2 Pathogenic Variants in "Apparently Sporadic" Pancreatic Cancer.
Jonathan R Brody, Alison P Klein

Cancer Res· September 2024

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Patient-Derived Models of Cancer in the NCI PDMC Consortium: Selection, Pitfalls, and Practical Recommendations.
Amber N Habowski, Deepthi P Budagavi, Sandra D Scherer, Arin B Aurora, Giuseppina Caligiuri, Jonathan R Brody

Cancers (Basel)· January 2024

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Strategies for the Management of Patients with Pancreatic Cancer with PARP Inhibitors.
Talia Golan, Maria Raitses-Gurevich, Tamar Beller, James Carroll, Jonathan R Brody

Cancer Treat Res· November 2023

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Micelle-Formulated Juglone Effectively Targets Pancreatic Cancer and Remodels the Tumor Microenvironment.
Vidhi M Shah, Syed Rizvi, Alexander Smith, Motoyuki Tsuda, Madeline Krieger, Jonathan R Brody

Pharmaceutics· November 2023

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