Publications by authors named "Jonathan D Glass"

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Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS.
Zachary T McEachin, Mingee Chung, Sabrina A Stratton, Changhee Han, Woo Jae Kim, Jonathan D Glass

Cell· November 2025

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Oligogenic structure of amyotrophic lateral sclerosis has genetic testing, counselling and therapeutic implications.
Alfredo Iacoangeli, Allison A Dilliott, Ahmad Al Khleifat, Peter M Andersen, Nazlı A Başak, Jonathan D Glass

J Neurol Neurosurg Psychiatry· September 2025

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Sporadic ALS induced pluripotent stem cell derived neurons reveal hallmarks of TDP-43 loss of function.
Jeffrey D Rothstein, Olivia Keeley, Caroline Warlick, Timothy M Miller, Cindy V Ly, Jonathan D Glass

Nat Commun· August 2025

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Molecular subtyping based on hippocampal cryptic exon burden reveals proteome-wide changes associated with TDP-43 pathology across the spectrum of LATE and Alzheimer's Disease.
Adam N Trautwig, Anantharaman Shantaraman, Mingee Chung, Eric B Dammer, Lingyan Ping, Jonathan D Glass

bioRxiv· July 2025

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Serious Neurologic Adverse Events in Tofersen Clinical Trials for Amyotrophic Lateral Sclerosis.
Alexandra Lovett, Sowmya Chary, Suma Babu, Gaëlle Bruneteau, Jonathan D Glass

Muscle Nerve· June 2025

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Network analysis of the cerebrospinal fluid proteome reveals shared and unique differences between sporadic and familial forms of amyotrophic lateral sclerosis.
Adam N Trautwig, Edward J Fox, Eric B Dammer, Anantharaman Shantaraman, Lingyan Ping, Jonathan D Glass

Mol Neurodegener· May 2025

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TDP-43 toxic gain of function links ALS, FTD and Alzheimer's Disease through splicing dysregulation.
Welmoed van Zuiden, Thea D Meimoun, Chen Bar, Aviad Siany, Lihi Moshe, Jonathan D Glass

bioRxiv· May 2025

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ALS Motor Observational Telemedicine Objective Rasch-Built Assessment: A Quantitative Scale for the Era of Teleneurology.
Christina N Fournier, Mark Levine, Karon Simmons, Rocío Carolina García-Santibáñez, Anne Rowland, Jonathan D Glass

Neurol Clin Pract· April 2025

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ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression.
Eleanor V Thomas, Changee Han, Woo Jae Kim, Seneshaw Asress, Yingjie Li, Jonathan D Glass

Ann Clin Transl Neurol· April 2025

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pTDP-43 levels correlate with cell type-specific molecular alterations in the prefrontal cortex of ALS/FTD patients.
Hsiao-Lin V Wang, Jian-Feng Xiang, Chenyang Yuan, Austin M Veire, Tania F Gendron, Jonathan D Glass

Proc Natl Acad Sci U S A· March 2025

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ALSUntangled #76: Wahls protocol.
Xiaoyan Li, Paul Wicks, Andrew Brown, Akhil Shivaprasad, Maxwell Greene, Jonathan D Glass

Amyotroph Lateral Scler Frontotemporal Degener· February 2025

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Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data.
Sara Saez-Atienzar, Cleide Dos Santos Souza, Ruth Chia, Selina N Beal, Ileana Lorenzini, Jonathan D Glass

Cell Genom· November 2024

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Sex-specific DNA methylation differences in Amyotrophic lateral sclerosis.
Olivia A Grant, Alfredo Iacoangeli, Ramona A J Zwamborn, Wouter van Rheenen, Ross Byrne, Jonathan D Glass

bioRxiv· November 2024

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Safety, tolerability, and pharmacokinetics of antisense oligonucleotide BIIB078 in adults with C9orf72-associated amyotrophic lateral sclerosis: a phase 1, randomised, double blinded, placebo-controlled, multiple ascending dose study.
Leonard H van den Berg, Jeffrey D Rothstein, Pamela J Shaw, Suma Babu, Michael Benatar, Jonathan D Glass

Lancet Neurol· September 2024

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Author Correction: The SOD1-mediated ALS phenotype shows a decoupling between age of symptom onset and disease duration.
Sarah Opie-Martin, Alfredo Iacoangeli, Simon D Topp, Olubunmi Abel, Keith Mayl, Jonathan D Glass

Nat Commun· July 2024

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pTDP-43 levels correlate with cell type specific molecular alterations in the prefrontal cortex of ALS/FTD patients.
Hsiao-Lin V Wang, Jian-Feng Xiang, Chenyang Yuan, Austin M Veire, Tania F Gendron, Jonathan D Glass

bioRxiv· June 2024

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ALSUntangled #73: Lion's Mane.
Maya Muhanna, Issac Lund, Mark Bromberg, Paul Wicks, Michael Benatar, Jonathan D Glass

Amyotroph Lateral Scler Frontotemporal Degener· May 2024

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The importance of understanding minimal important difference for ALSFRS-R: A reply to 'Do we really need to calculate a minimal important difference for ALSFRS-R?' https://doi.org/10.1080/21678421.2023.2248199.
Christina N Fournier, Jonathan D Glass

Amyotroph Lateral Scler Frontotemporal Degener· February 2024

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Mis-spliced transcripts generate de novo proteins in TDP-43-related ALS/FTD.
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Jonathan D Glass

Sci Transl Med· February 2024

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Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains.
Mingee Chung, E Kathleen Carter, Austin M Veire, Eric B Dammer, Jianjun Chang, Jonathan D Glass

Acta Neuropathol· February 2024

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Toward a generalizable machine learning workflow for neurodegenerative disease staging with focus on neurofibrillary tangles.
Juan C Vizcarra, Thomas M Pearce, Brittany N Dugger, Michael J Keiser, Marla Gearing, Jonathan D Glass

Acta Neuropathol Commun· December 2023

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Genetic variability in sporadic amyotrophic lateral sclerosis.
Sien Hilde Van Daele, Matthieu Moisse, Joke J F A van Vugt, Ramona A J Zwamborn, Rick van der Spek, Jonathan D Glass

Brain· September 2023

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Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival.
Brett N Adey, Johnathan Cooper-Knock, Ahmad Al Khleifat, Isabella Fogh, Philip van Damme, Jonathan D Glass

Front Cell Neurosci· March 2023

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Mis-spliced transcripts generate proteins in TDP-43-related ALS/FTD.
Sahba Seddighi, Yue A Qi, Anna-Leigh Brown, Oscar G Wilkins, Colleen Bereda, Jonathan D Glass

bioRxiv· January 2023

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Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data.
Ahmad Al Khleifat, Alfredo Iacoangeli, Ashley R Jones, Joke J F A van Vugt, Matthieu Moisse, Jonathan D Glass

Front Cell Neurosci· December 2022

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