Publications by authors named "Jonathan D Humphries"

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CLN7 protein functions at the interface between endolysosomes and stress granules to promote cell survival.
Aseel Sharaireh, Marta Guevara-Ferrer, Anna M Ludlaim, Jonathan D Humphries, Alexander M Phillips

Cell Death Dis· October 2025

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A TRPV4-dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration.
Ernest Iu, Alexander Bogatch, Wenjun Deng, Jonathan D Humphries, Changsong Yang, Martin J Humphries

bioRxiv· March 2025

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The extracellular matrix component perlecan/HSPG2 regulates radioresistance in prostate cancer cells.
Ivana Samaržija, Vasyl Lukiyanchuk, Marija Lončarić, Anja Rac-Justament, Nikolina Stojanović, Jonathan D Humphries, Martin J Humphries

Front Cell Dev Biol· August 2024

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Transcriptional response of the heart to vagus nerve stimulation.
Daniel O Kellett, Qadeer Aziz, Jonathan D Humphries, Alla Korsak, Alice Braga

Physiol Genomics· February 2024

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Transcriptional response of the heart to vagus nerve stimulation.
Daniel O Kellett, Qadeer Aziz, Jonathan D Humphries, Alla Korsak, Alice Braga

Physiol Genomics· February 2024

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Lineage Plasticity in SCLC Generates Non-Neuroendocrine Cells Primed for Vasculogenic Mimicry.
Sarah M Pearsall, Stuart C Williamson, Sam Humphrey, Ellyn Hughes, Derrick Morgan, Jonathan D Humphries, Martin J Humphries

J Thorac Oncol· October 2023

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Talin2 and KANK2 functionally interact to regulate microtubule dynamics, paclitaxel sensitivity and cell migration in the MDA-MB-435S melanoma cell line.
Marija Lončarić, Nikolina Stojanović, Anja Rac-Justament, Kaatje Coopmans, Dragomira Majhen, Jonathan D Humphries, Martin J Humphries

Cell Mol Biol Lett· July 2023

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Pancreatic ductal adenocarcinoma cells employ integrin α6β4 to form hemidesmosomes and regulate cell proliferation.
Jonathan D Humphries, Junzhe Zha, Jessica Burns, Janet A Askari, Christopher R Below, Martin J Humphries

Matrix Biol· June 2022

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A microenvironment-inspired synthetic three-dimensional model for pancreatic ductal adenocarcinoma organoids.
Christopher R Below, Joanna Kelly, Alexander Brown, Jonathan D Humphries, Colin Hutton, Martin J Humphries

Nat Mater· January 2022

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The Tongue Squamous Carcinoma Cell Line Cal27 Primarily Employs Integrin α6β4-Containing Type II Hemidesmosomes for Adhesion Which Contribute to Anticancer Drug Sensitivity.
Ana Tadijan, Jonathan D Humphries, Ivana Samaržija, Nikolina Stojanović, Junzhe Zha, Martin J Humphries

Front Cell Dev Biol· December 2021

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A SNAI2-PEAK1-INHBA stromal axis drives progression and lapatinib resistance in HER2-positive breast cancer by supporting subpopulations of tumor cells positive for antiapoptotic and stress signaling markers.
Sarkis Hamalian, Robert Güth, Farhana Runa, Francesca Sanchez, Eric Vickers, Jonathan D Humphries, Martin J Humphries

Oncogene· August 2021

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Talin mechanosensitivity is modulated by a direct interaction with cyclin-dependent kinase-1.
Rosemarie E Gough, Matthew C Jones, Thomas Zacharchenko, Shimin Le, Miao Yu, Jonathan D Humphries, Martin J Humphries

J Biol Chem· July 2021

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KANK family proteins in cancer.
Ana Tadijan, Ivana Samaržija, Jonathan D Humphries, Martin J Humphries, Andreja Ambriović-Ristov

Int J Biochem Cell Biol· February 2021

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Basement membrane ligands initiate distinct signalling networks to direct cell shape.
Michael J Randles, Franziska Lausecker, Jonathan D Humphries, Adam Byron, Simon J Clark, Martin J Humphries

Matrix Biol· August 2020

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Topological features of integrin adhesion complexes revealed by multiplexed proximity biotinylation.
Megan R Chastney, Craig Lawless, Jonathan D Humphries, Stacey Warwood, Matthew C Jones, Martin J Humphries

J Cell Biol· August 2020

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Global proteomic analysis of insulin receptor interactors in glomerular podocytes.
Salman B Hosawi, Jonathan D Humphries, Richard J Coward, David Knight, Martin J Humphries

Wellcome Open Res· August 2020

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Integrin Crosstalk Contributes to the Complexity of Signalling and Unpredictable Cancer Cell Fates.
Ivana Samaržija, Ana Dekanić, Jonathan D Humphries, Mladen Paradžik, Nikolina Stojanović, Martin J Humphries

Cancers (Basel)· July 2020

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KANK2 Links αVβ5 Focal Adhesions to Microtubules and Regulates Sensitivity to Microtubule Poisons and Cell Migration.
Mladen Paradžik, Jonathan D Humphries, Nikolina Stojanović, Davor Nestić, Dragomira Majhen, Martin J Humphries

Front Cell Dev Biol· March 2020

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Clathrin-containing adhesion complexes.
John G Lock, Francesco Baschieri, Matthew C Jones, Jonathan D Humphries, Guillaume Montagnac, Martin J Humphries

J Cell Biol· July 2019

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Signal transduction via integrin adhesion complexes.
Jonathan D Humphries, Megan R Chastney, Janet A Askari, Martin J Humphries

Curr Opin Cell Biol· February 2019

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Cell adhesion is regulated by CDK1 during the cell cycle.
Matthew C Jones, Janet A Askari, Jonathan D Humphries, Martin J Humphries

J Cell Biol· September 2018

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Characterization of the Phospho-Adhesome by Mass Spectrometry-Based Proteomics.
Joseph Robertson, Jonathan D Humphries, Nikki R Paul, Stacey Warwood, David Knight, Martin J Humphries

Methods Mol Biol· April 2018

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The integrin adhesome network at a glance.
Edward R Horton, Jonathan D Humphries, Jenny James, Matthew C Jones, Janet A Askari, Martin J Humphries

J Cell Sci· November 2016

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Mechanosensitivity of integrin adhesion complexes: role of the consensus adhesome.
Edward R Horton, Pablo Astudillo, Martin J Humphries, Jonathan D Humphries

Exp Cell Res· April 2016

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Modulation of FAK and Src adhesion signaling occurs independently of adhesion complex composition.
Edward R Horton, Jonathan D Humphries, Ben Stutchbury, Guillaume Jacquemet, Christoph Ballestrem, Martin J Humphries

J Cell Biol· February 2016

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