Publications by authors named "Jonathan L Coloff"

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Ceramide-induced Endoplasmic Reticulum Stress as a Targetable Vulnerability in Endocrine Therapy-Resistant Breast Cancer.
Purab Pal, Shweta Chitkara, Godwin K Sarpey, Fatimah Alani, Huiping Zhao, Jonathan L Coloff

bioRxiv· August 2025

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Microenvironmental arginine restriction sensitizes pancreatic cancers to polyunsaturated fatty acids by suppression of lipid synthesis.
Patrick B Jonker, Mumina Sadullozoda, Guillaume Cognet, Juan J Apiz Saab, Kelly H Sokol, Jonathan L Coloff

bioRxiv· March 2025

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Catabolism of extracellular glutathione supplies amino acids to support tumor growth.
Fabio Hecht, Marco Zocchi, Emily T Tuttle, Nathan P Ward, Bradley Smith, Jonathan L Coloff

bioRxiv· October 2024

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ASCT2 is a major contributor to serine uptake in cancer cells.
Kelly O Conger, Christopher Chidley, Mete Emir Ozgurses, Huiping Zhao, Yumi Kim, Jonathan L Coloff

Cell Rep· August 2024

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Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
Vipin Rawat, Patrick DeLear, Prarthana Prashanth, Mete Emir Ozgurses, Anteneh Tebeje, Jonathan L Coloff

JCI Insight· May 2024

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ASCT2 is the primary serine transporter in cancer cells.
Kelly O Conger, Christopher Chidley, Mete Emir Ozgurses, Huiping Zhao, Yumi Kim, Jonathan L Coloff

bioRxiv· October 2023

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Drug screening in human physiologic medium identifies uric acid as an inhibitor of rigosertib efficacy.
Vipin Rawat, Patrick DeLear, Prarthana Prashanth, Mete Emir Ozgurses, Anteneh Tebeje, Jonathan L Coloff

bioRxiv· July 2023

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SOX2 mediates metabolic reprogramming of prostate cancer cells.
Larischa de Wet, Anthony Williams, Marc Gillard, Steven Kregel, Sophia Lamperis, Jonathan L Coloff

Oncogene· February 2022

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Correction to: SOX2 mediates metabolic reprogramming of prostate cancer cells.
Larischa de Wet, Anthony Williams, Marc Gillard, Steven Kregel, Sophia Lamperis, Jonathan L Coloff

Oncogene· February 2022

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Lineage-specific silencing of PSAT1 induces serine auxotrophy and sensitivity to dietary serine starvation in luminal breast tumors.
Bo-Hyun Choi, Vipin Rawat, Jenny Högström, Philippa A Burns, Kelly O Conger, Jonathan L Coloff

Cell Rep· January 2022

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Differential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells.
Mark A Keibler, Wentao Dong, Keegan D Korthauer, Aaron M Hosios, Sun Jin Moon, Jonathan L Coloff

FEBS J· October 2021

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PHGDH supports liver ceramide synthesis and sustains lipid homeostasis.
Yun Pyo Kang, Aimee Falzone, Min Liu, Paloma González-Sánchez, Bo-Hyun Choi, Jonathan L Coloff

Cancer Metab· June 2020

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Deubiquitinases Maintain Protein Homeostasis and Survival of Cancer Cells upon Glutathione Depletion.
Isaac S Harris, Jennifer E Endress, Jonathan L Coloff, Laura M Selfors, Samuel K McBrayer

Cell Metab· May 2019

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The Diverse Functions of Non-Essential Amino Acids in Cancer.
Bo-Hyun Choi, Jonathan L Coloff

Cancers (Basel)· May 2019

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Glutamate Dehydrogenase to the Rescue.
Jonathan L Coloff

Mol Cell· January 2018

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Identification of cancer genes that are independent of dominant proliferation and lineage programs.
Laura M Selfors, Daniel G Stover, Isaac S Harris, Joan S Brugge, Jonathan L Coloff

Proc Natl Acad Sci U S A· December 2017

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Akt regulation of glycolysis mediates bioenergetic stability in epithelial cells.
Yin P Hung, Carolyn Teragawa, Nont Kosaisawe, Taryn E Gillies, Michael Pargett, Jonathan L Coloff

Elife· December 2017

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Metabolic changes promote rejection of oncogenic cells.
Jonathan L Coloff, Joan S Brugge

Nat Cell Biol· April 2017

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Starved epithelial cells uptake extracellular matrix for survival.
Taru Muranen, Marcin P Iwanicki, Natasha L Curry, Julie Hwang, Cory D DuBois, Jonathan L Coloff

Nat Commun· January 2017

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The Role of Proliferation in Determining Response to Neoadjuvant Chemotherapy in Breast Cancer: A Gene Expression-Based Meta-Analysis.
Daniel G Stover, Jonathan L Coloff, William T Barry, Joan S Brugge, Eric P Winer

Clin Cancer Res· December 2016

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ERK and p38 MAPK Activities Determine Sensitivity to PI3K/mTOR Inhibition via Regulation of MYC and YAP.
Taru Muranen, Laura M Selfors, Julie Hwang, Lisa L Gallegos, Jonathan L Coloff

Cancer Res· December 2016

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Coping with the metabolic stress of leaving home.
Jonathan L Coloff, Joan S Brugge

Cell Res· July 2016

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Differential Glutamate Metabolism in Proliferating and Quiescent Mammary Epithelial Cells.
Jonathan L Coloff, J Patrick Murphy, Craig R Braun, Isaac S Harris, Laura M Shelton

Cell Metab· May 2016

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Corrigendum: Chaperone-mediated autophagy degrades mutant p53.
Helin Vakifahmetoglu-Norberg, Minsu Kim, Hong-Guang Xia, Marcin P Iwanicki, Dimitry Ofengeim, Jonathan L Coloff

Genes Dev· April 2016

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Correction: Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.
Hong-Guang Xia, Ayaz Najafov, Jiefei Geng, Lorena Galan-Acosta, Xuemei Han, Jonathan L Coloff

J Cell Biol· March 2016

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