Publications by authors named "Jonathan Rothbard"

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Sjögren Syndrome Candidate Autoantigen AQP5 Triggers AQP4 CNS Autoimmunity Through Self-Antigen Mimicry.
Carson E Moseley, Sharon Sagan, Juliano A Boquett, Collin M Spencer, Jill A Hollenbach, Jonathan B Rothbard

Neurol Neuroimmunol Neuroinflamm· January 2026

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Do amyloid fibrils induce inflammation, or does inflammation generate amyloid fibrils?
Jonathan B Rothbard

Proc Natl Acad Sci U S A· October 2022

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Small Heat Shock Proteins, Amyloid Fibrils, and Nicotine Stimulate a Common Immune Suppressive Pathway with Implications for Future Therapies.
Jonathan B Rothbard, Michael P Kurnellas, Shalina S Ousman, Sara Brownell, Jesse J Rothbard

Cold Spring Harb Perspect Med· July 2019

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An amyloidogenic hexapeptide derived from amylin attenuates inflammation and acute lung injury in murine sepsis.
Sidharth Mahapatra, Lihua Ying, Peggy Pui-Kay Ho, Michael Kurnellas, Jonathan Rothbard

PLoS One· December 2018

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Identification of a common immune regulatory pathway induced by small heat shock proteins, amyloid fibrils, and nicotine.
Jonathan B Rothbard, Jesse J Rothbard, Luis Soares, C Garrison Fathman, Lawrence Steinman

Proc Natl Acad Sci U S A· July 2018

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Genetic background modulates outcome of therapeutic amyloid peptides in treatment of neuroinflammation.
Allison Kraus, Brent Race, Katie Phillips, Clayton Winkler, Greg Saturday, Jonathan B Rothbard

J Neuroimmunol· September 2016

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Self-Assembling Peptides Form Immune Suppressive Amyloid Fibrils Effective in Autoimmune Encephalomyelitis.
Michael P Kurnellas, Jonathan B Rothbard, Lawrence Steinman

Curr Top Behav Neurosci· December 2015

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Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease.
Michael Phillip Kurnellas, Eliver Eid Bou Ghosn, Jill M Schartner, Jeanette Baker, Jesse J Rothbard, Jonathan B Rothbard

Proc Natl Acad Sci U S A· December 2015

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Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2.
Syed Sohail Ahmed, Wayne Volkmuth, José Duca, Lorenzo Corti, Michele Pallaoro, Jonathan Rothbard

Sci Transl Med· July 2015

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Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease.
Michael P Kurnellas, Jill M Schartner, C Garrison Fathman, Ann Jagger, Lawrence Steinman, Jonathan B Rothbard

J Exp Med· August 2014

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Janus faces of amyloid proteins in neuroinflammation.
Lawrence Steinman, Jonathan B Rothbard, Michael P Kurnellas

J Clin Immunol· July 2014

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CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients.
Que Lan Quach, Luanne M Metz, Jenna C Thomas, Jonathan B Rothbard, Lawrence Steinman

Mult Scler· December 2013

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Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation.
Michael P Kurnellas, Chris M Adams, Raymond A Sobel, Lawrence Steinman, Jonathan B Rothbard

Sci Transl Med· April 2013

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Piet Mondrian's trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011.
Lawrence Steinman, Robert C Axtell, Donald Barbieri, Roopa Bhat, Sara E Brownell, Jonathan B Rothbard

Mult Scler· January 2013

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Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis.
Michael P Kurnellas, Sara E Brownell, Leon Su, Andrey V Malkovskiy, Jayakumar Rajadas, Jonathan B Rothbard

J Biol Chem· October 2012

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Therapeutic effects of systemic administration of chaperone αB-crystallin associated with binding proinflammatory plasma proteins.
Jonathan B Rothbard, Michael P Kurnellas, Sara Brownell, Chris M Adams, Leon Su

J Biol Chem· March 2012

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Systemic augmentation of alphaB-crystallin provides therapeutic benefit twelve hours post-stroke onset via immune modulation.
Ahmet Arac, Sara E Brownell, Jonathan B Rothbard, Charlene Chen, Rose M Ko

Proc Natl Acad Sci U S A· August 2011

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αB-crystallin improves murine cardiac function and attenuates apoptosis in human endothelial cells exposed to ischemia-reperfusion.
Jeffrey B Velotta, Naoyuki Kimura, Stephanie H Chang, Jaehoon Chung, Satoshi Itoh, Jonathan Rothbard

Ann Thorac Surg· June 2011

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Chaperone activity of α B-crystallin is responsible for its incorrect assignment as an autoantigen in multiple sclerosis.
Jonathan B Rothbard, Xiaoyan Zhao, Orr Sharpe, Michael J Strohman, Michael Kurnellas

J Immunol· April 2011

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Quantitation of cellular and topical uptake of luciferin-oligoarginine conjugates.
Jonathan B Rothbard, Lisa R Jones

Methods Mol Biol· February 2011

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Real-time analysis of uptake and bioactivatable cleavage of luciferin-transporter conjugates in transgenic reporter mice.
Paul A Wender, Elena A Goun, Lisa R Jones, Thomas H Pillow, Jonathan B Rothbard

Proc Natl Acad Sci U S A· June 2007

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Molecular transporters: synthesis of oligoguanidinium transporters and their application to drug delivery and real-time imaging.
Elena A Goun, Thomas H Pillow, Lisa R Jones, Jonathan B Rothbard, Paul A Wender

Chembiochem· October 2006

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Releasable luciferin-transporter conjugates: tools for the real-time analysis of cellular uptake and release.
Lisa R Jones, Elena A Goun, Rajesh Shinde, Jonathan B Rothbard, Christopher H Contag

J Am Chem Soc· May 2006

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Dendrimeric molecular transporters: synthesis and evaluation of tunable polyguanidino dendrimers that facilitate cellular uptake.
Paul A Wender, Erik Kreider, Erin T Pelkey, Jonathan Rothbard, Christopher L Vandeusen

Org Lett· October 2005

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Binding of biotinylated peptides to MHC class II proteins on cell surfaces.
Jonathan B Rothbard, Robert Busch

Curr Protoc Immunol· May 2001

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