Publications by authors named "Jonathon LeFaive"

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Whole-genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
Runjia Li, Sarah A Gagliano Taliun, Kevin Liao, Matthew Flickinger, Janet L Sobell, Jonathon LeFaive

HGG Adv· August 2025

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Whole genome sequence-based association analysis of African American individuals with bipolar disorder and schizophrenia.
Runjia Li, Sarah A Gagliano Taliun, Kevin Liao, Matthew Flickinger, Janet L Sobell, Jonathon LeFaive

medRxiv· February 2025

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Imputation Server PGS: an automated approach to calculate polygenic risk scores on imputation servers.
Lukas Forer, Daniel Taliun, Jonathon LeFaive, Albert V Smith, Andrew P Boughton

Nucleic Acids Res· July 2024

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Tutorial: a statistical genetics guide to identifying HLA alleles driving complex disease.
Saori Sakaue, Saisriram Gurajala, Michelle Curtis, Yang Luo, Wanson Choi, Jonathon LeFaive

Nat Protoc· September 2023

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The phenotype-genotype reference map: Improving biobank data science through replication.
Lisa Bastarache, Sarah Delozier, Anita Pandit, Jing He, Adam Lewis, Jonathon LeFaive

Am J Hum Genet· September 2023

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FixItFelix: improving genomic analysis by fixing reference errors.
Sairam Behera, Jonathon LeFaive, Peter Orchard, Medhat Mahmoud, Luis F Paulin

Genome Biol· February 2023

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Extent to which array genotyping and imputation with large reference panels approximate deep whole-genome sequencing.
Sarah C Hanks, Lukas Forer, Sebastian Schönherr, Jonathon LeFaive, Taylor Martins

Am J Hum Genet· September 2022

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Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.
Tanika N Kelly, Xiao Sun, Karen Y He, Michael R Brown, Sarah A Gagliano Taliun, Jonathon LeFaive

Hypertension· August 2022

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Meta-imputation: An efficient method to combine genotype data after imputation with multiple reference panels.
Ketian Yu, Sayantan Das, Jonathon LeFaive, Alan Kwong, Jacob Pleiness

Am J Hum Genet· June 2022

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Telomere length is not a main factor for the development of islet autoimmunity and type 1 diabetes in the TEDDY study.
Carina Törn, Xiang Liu, Suna Onengut-Gumuscu, Kevin M Counts, Jose Leonardo Moreno, Jonathon LeFaive

Sci Rep· March 2022

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Sparse allele vectors and the savvy software suite.
Jonathon LeFaive, Albert V Smith, Hyun Min Kang, Gonçalo Abecasis

Bioinformatics· November 2021

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Genome-wide association study of cardiac troponin I in the general population.
Marta R Moksnes, Helge Røsjø, Anne Richmond, Magnus N Lyngbakken, Sarah E Graham, Jonathon LeFaive

Hum Mol Genet· October 2021

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Robust, flexible, and scalable tests for Hardy-Weinberg equilibrium across diverse ancestries.
Alan M Kwong, Thomas W Blackwell, Jonathon LeFaive, Mariza de Andrade, John Barnard

Genetics· May 2021

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
Daniel Taliun, Daniel N Harris, Michael D Kessler, Jedidiah Carlson, Zachary A Szpiech, Jonathon LeFaive

Nature· February 2021

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Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.
Jonas B Nielsen, Oren Rom, Ida Surakka, Sarah E Graham, Wei Zhou, Jonathon LeFaive

Nat Commun· December 2020

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Scalable generalized linear mixed model for region-based association tests in large biobanks and cohorts.
Wei Zhou, Zhangchen Zhao, Jonas B Nielsen, Lars G Fritsche, Jonathon LeFaive

Nat Genet· June 2020

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Exploring various polygenic risk scores for skin cancer in the phenomes of the Michigan genomics initiative and the UK Biobank with a visual catalog: PRSWeb.
Lars G Fritsche, Lauren J Beesley, Peter VandeHaar, Robert B Peng, Maxwell Salvatore, Jonathon LeFaive

PLoS Genet· June 2019

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Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies.
Wei Zhou, Jonas B Nielsen, Lars G Fritsche, Rounak Dey, Maiken E Gabrielsen, Jonathon LeFaive

Nat Genet· September 2018

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