Publications by authors named "Michael D Kessler"

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Variant Classification Using Proteomics-Informed Large Language Models Increases Power of Rare Variant Association Studies and Enhances Target Discovery.
Christopher E Gillies, Joelle Mbatchou, Lukas Habegger, Michael D Kessler, Suying Bao

Genet Epidemiol· December 2025

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Epigenetic profiling reveals key super-enhancer networks driving oncogenesis in HPV-positive HNSCC.
Fernando T Zamuner, Spencer S Chan, Michael D Kessler, Ilya E Vorontsov, Andrey Loginov

iScience· November 2025

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Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.
Yasminka A Jakubek, Xiaolong Ma, Adrienne M Stilp, Fulong Yu, Jason Bacon, Michael D Kessler

Am J Hum Genet· February 2025

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Author Correction: A deep catalogue of protein-coding variation in 983,578 individuals.
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Michael D Kessler

Nature· January 2025

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Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes.
Michael D Kessler, Amy Damask, Sean O'Keeffe, Nilanjana Banerjee, Dadong Li

Nature· January 2025

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SpliceMutr Enables Pan-Cancer Analysis of Splicing-Derived Neoantigen Burden in Tumors.
Theron Palmer, Michael D Kessler, Xiaoshan M Shao, Archana Balan, Mark Yarchoan

Cancer Res Commun· December 2024

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Genetic risk factors for COVID-19 and influenza are largely distinct.
Jack A Kosmicki, Anthony Marcketta, Deepika Sharma, Silvio Alessandro Di Gioia, Samantha Batista, Michael D Kessler

Nat Genet· August 2024

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A deep catalogue of protein-coding variation in 983,578 individuals.
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Chuanyi Zhang, Michael D Kessler

Nature· July 2024

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A deep catalog of protein-coding variation in 985,830 individuals.
Kathie Y Sun, Xiaodong Bai, Siying Chen, Suying Bao, Manav Kapoor, Michael D Kessler

bioRxiv· November 2023

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Rare coding variants in CHRNB2 reduce the likelihood of smoking.
Veera M Rajagopal, Kyoko Watanabe, Joelle Mbatchou, Ariane Ayer, Peter Quon, Michael D Kessler

Nat Genet· July 2023

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Author Correction: Common and rare variant associations with clonal haematopoiesis phenotypes.
Michael D Kessler, Amy Damask, Sean O'Keeffe, Nilanjana Banerjee, Dadong Li

Nature· March 2023

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Common and rare variant associations with clonal haematopoiesis phenotypes.
Michael D Kessler, Amy Damask, Sean O'Keeffe, Nilanjana Banerjee, Dadong Li

Nature· December 2022

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Activating STING1-dependent immune signaling in mutant and wild-type acute myeloid leukemia.
Aksinija A Kogan, Michael J Topper, Anna J Dellomo, Lora Stojanovic, Lena J McLaughlin, Michael D Kessler

Proc Natl Acad Sci U S A· July 2022

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Ten quick tips for deep learning in biology.
Benjamin D Lee, Anthony Gitter, Casey S Greene, Sebastian Raschka, Finlay Maguire, Michael D Kessler

PLoS Comput Biol· March 2022

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Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry.
Nicholas W Bateman, Christopher M Tarney, Tamara S Abulez, Brian L Hood, Kelly A Conrads, Michael D Kessler

iScience· January 2022

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Exome sequencing and analysis of 454,787 UK Biobank participants.
Joshua D Backman, Alexander H Li, Anthony Marcketta, Dylan Sun, Joelle Mbatchou, Michael D Kessler

Nature· November 2021

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Transfer learning between preclinical models and human tumors identifies a conserved NK cell activation signature in anti-CTLA-4 responsive tumors.
Emily F Davis-Marcisak, Allison A Fitzgerald, Michael D Kessler, Ludmila Danilova, Elizabeth M Jaffee

Genome Med· August 2021

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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program.
Daniel Taliun, Daniel N Harris, Michael D Kessler, Jedidiah Carlson, Zachary A Szpiech

Nature· February 2021

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Matrix factorization and transfer learning uncover regulatory biology across multiple single-cell ATAC-seq data sets.
Rossin Erbe, Michael D Kessler, Alexander V Favorov, Hariharan Easwaran, Daria A Gaykalova

Nucleic Acids Res· July 2020

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Evolutionary history of modern Samoans.
Daniel N Harris, Michael D Kessler, Amol C Shetty, Daniel E Weeks, Ryan L Minster

Proc Natl Acad Sci U S A· April 2020

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De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.
Michael D Kessler, Douglas P Loesch, James A Perry, Nancy L Heard-Costa, Daniel Taliun

Proc Natl Acad Sci U S A· February 2020

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Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences.
Michael D Kessler, Nicholas W Bateman, Thomas P Conrads, George L Maxwell, Julie C Dunning Hotopp

Cancer· June 2019

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Improving Cancer Detection and Treatment with Liquid Biopsies and ptDNA.
Michael D Kessler, Nisha R Pawar, Stuart S Martin, Toni M Antalis, Timothy D O'Connor

Trends Cancer· September 2018

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The Evolution of Polymorphic Hybrid Incompatibilities in House Mice.
Erica L Larson, Dan Vanderpool, Brice A J Sarver, Colin Callahan, Sara Keeble, Michael D Kessler

Genetics· July 2018

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Evolutionary genomic dynamics of Peruvians before, during, and after the Inca Empire.
Daniel N Harris, Wei Song, Amol C Shetty, Kelly S Levano, Omar Cáceres, Michael D Kessler

Proc Natl Acad Sci U S A· July 2018

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