Publications by authors named "Joshua D Backman"

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Genome-wide association study meta-analysis provides insights into the etiology of heart failure and its subtypes.
Albert Henry, Xiaodong Mo, Chris Finan, Mark D Chaffin, Doug Speed, Joshua D Backman

Nat Genet· April 2025

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Genome-wide association analysis provides insights into the molecular etiology of dilated cardiomyopathy.
Sean L Zheng, Albert Henry, Douglas Cannie, Michael Lee, David Miller, Joshua D Backman

Nat Genet· December 2024

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Genome-wide association and multi-trait analyses characterize the common genetic architecture of heart failure.
Michael G Levin, Noah L Tsao, Pankhuri Singhal, Chang Liu, Ha My T Vy, Joshua D Backman

Nat Commun· November 2022

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Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease.
Julie E Horowitz, Jack A Kosmicki, Amy Damask, Deepika Sharma, Genevieve H L Roberts, Joshua D Backman

Nat Genet· April 2022

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The genomics of heart failure: design and rationale of the HERMES consortium.
R Thomas Lumbers, Sonia Shah, Honghuang Lin, Tomasz Czuba, Albert Henry, Joshua D Backman

ESC Heart Fail· December 2021

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Exome sequencing and analysis of 454,787 UK Biobank participants.
Joshua D Backman, Alexander H Li, Anthony Marcketta, Dylan Sun, Joelle Mbatchou

Nature· November 2021

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Genome-wide association analysis of serum alanine and aspartate aminotransferase, and the modifying effects of BMI in 388k European individuals.
Chuan Gao, Anthony Marcketta, Joshua D Backman, Colm O'Dushlaine, Jeffrey Staples

Genet Epidemiol· September 2021

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Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals.
Jack A Kosmicki, Julie E Horowitz, Nilanjana Banerjee, Rouel Lanche, Anthony Marcketta, Joshua D Backman

Am J Hum Genet· July 2021

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Genomewide Association Study of Platelet Reactivity and Cardiovascular Response in Patients Treated With Clopidogrel: A Study by the International Clopidogrel Pharmacogenomics Consortium.
Shefali Setia Verma, Thomas O Bergmeijer, Li Gong, Jean-Luc Reny, Joshua P Lewis, Joshua D Backman

Clin Pharmacol Ther· November 2020

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Exome sequencing and characterization of 49,960 individuals in the UK Biobank.
Cristopher V Van Hout, Ioanna Tachmazidou, Joshua D Backman, Joshua D Hoffman, Daren Liu

Nature· October 2020

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Pharmacogenomic polygenic response score predicts ischaemic events and cardiovascular mortality in clopidogrel-treated patients.
Joshua P Lewis, Joshua D Backman, Jean-Luc Reny, Thomas O Bergmeijer, Braxton D Mitchell

Eur Heart J Cardiovasc Pharmacother· July 2020

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Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Sonia Shah, Albert Henry, Carolina Roselli, Honghuang Lin, Garðar Sveinbjörnsson, Joshua D Backman

Nat Commun· January 2020

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Exome-chip meta-analysis identifies association between variation in ANKRD26 and platelet aggregation.
Ming-Huei Chen, Lisa R Yanek, Joshua D Backman, John D Eicher, Jennifer E Huffman

Platelets· April 2019

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Biobank-driven genomic discovery yields new insight into atrial fibrillation biology.
Jonas B Nielsen, Rosa B Thorolfsdottir, Lars G Fritsche, Wei Zhou, Morten W Skov, Joshua D Backman

Nat Genet· September 2018

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Genome-wide analysis of clopidogrel active metabolite levels identifies novel variants that influence antiplatelet response.
Joshua D Backman, Jeffrey R O'Connell, Keith Tanner, Cody J Peer, William D Figg

Pharmacogenet Genomics· April 2017

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From Genotype to Phenotype: Nonsense Variants in SLC13A1 Are Associated with Decreased Serum Sulfate and Increased Serum Aminotransferases.
Christina G Tise, James A Perry, Leslie E Anforth, Mary A Pavlovich, Joshua D Backman

G3 (Bethesda)· September 2016

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Genetic Variation in the Platelet Endothelial Aggregation Receptor 1 Gene Results in Endothelial Dysfunction.
Adam S Fisch, Laura M Yerges-Armstrong, Joshua D Backman, Hong Wang, Patrick Donnelly

PLoS One· May 2016

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