Publications by authors named "Jorge Naciff"

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Identifying chemicals based on receptor binding/bioactivation/mechanistic explanation associated with potential to elicit hepatotoxicity and to support structure activity relationship-based read-across.
Shengde Wu, George Daston, Jane Rose, Karen Blackburn, Joan Fisher, Jorge Naciff

Curr Res Toxicol· June 2023

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Structure-activity relationship read-across and transcriptomics for branched carboxylic acids.
Shengde Wu, Corie Ellison, Jorge Naciff, Michael Karb, Cindy Obringer

Toxicol Sci· February 2023

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Letter to the editor.
Cathy C Lester, Shengde Wu, Jorge Naciff, Michael Laufersweiler, George Daston

Toxicol Sci· January 2023

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Article title: Transcriptional profiling efficacy to define biological activity similarity for cosmetic ingredients' safety assessment based on next-generation read-across.
Jorge M Naciff, Yuquing K Shan, Xiaohong Wang, George P Daston

Front Toxicol· December 2022

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Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Gladys Ouedraogo, Camilla Alexander-White, Dagmar Bury, Harvey J Clewell, Mark Cronin, Jorge Naciff

Regul Toxicol Pharmacol· July 2022

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A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment.
Camilla Alexander-White, Dagmar Bury, Mark Cronin, Matthew Dent, Eric Hack, Jorge Naciff

Regul Toxicol Pharmacol· March 2022

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Incorporation of in vitro techniques for botanicals dietary supplement safety assessment - Towards evaluation of developmental and reproductive toxicity (DART).
Karen M VanderMolen, Jorge M Naciff, Kevin Kennedy, Annie Otto-Bruc, Yuqing Shan

Food Chem Toxicol· October 2020

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Use of connectivity mapping to support read across: A deeper dive using data from 186 chemicals, 19 cell lines and 2 case studies.
K Nadira De Abrew, Yuqing K Shan, Xiaohong Wang, Jesse M Krailler, Raghunandan M Kainkaryam, Jorge M Naciff

Toxicology· July 2019

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Toward Good Read-Across Practice (GRAP) guidance.
Nicholas Ball, Mark T D Cronin, Jie Shen, Karen Blackburn, Ewan D Booth, Jorge M Naciff

ALTEX· December 2016

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Grouping 34 Chemicals Based on Mode of Action Using Connectivity Mapping.
K Nadira De Abrew, Raghunandan M Kainkaryam, Yuqing K Shan, Gary J Overmann, Raja S Settivari, Jorge M Naciff

Toxicol Sci· June 2016

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Dose- and Time-Dependent Transcriptional Response of Ishikawa Cells Exposed to Genistein.
Jorge M Naciff, Zubin S Khambatta, Gregory J Carr, Jay P Tiesman, David W Singleton

Toxicol Sci· May 2016

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A strategy for safety assessment of chemicals with data gaps for developmental and/or reproductive toxicity.
Karen Blackburn, George Daston, Joan Fisher, Cathy Lester, Jorge M Naciff

Regul Toxicol Pharmacol· July 2015

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In response: ecotoxicogenomics addressing future needs: an industry perspective.
Donald J Versteeg, Jorge M Naciff

Environ Toxicol Chem· April 2015

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A novel transcriptomics based in vitro method to compare and predict hepatotoxicity based on mode of action.
K Nadira De Abrew, Gary J Overmann, Rachel L Adams, Jay P Tiesman, John Dunavent, Jorge M Naciff

Toxicology· February 2015

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Framework for identifying chemicals with structural features associated with the potential to act as developmental or reproductive toxicants.
Shengde Wu, Joan Fisher, Jorge Naciff, Michael Laufersweiler, Cathy Lester

Chem Res Toxicol· December 2013

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Effects of transplacental 17-α-ethynyl estradiol or bisphenol A on the developmental profile of steroidogenic acute regulatory protein in the rat testis.
Karla A Horstman, Jorge M Naciff, Gary J Overmann, Leslie M Foertsch, Brian D Richardson

Birth Defects Res B Dev Reprod Toxicol· August 2012

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Case studies to test: A framework for using structural, reactivity, metabolic and physicochemical similarity to evaluate the suitability of analogs for SAR-based toxicological assessments.
Karen Blackburn, Donald Bjerke, George Daston, Susan Felter, Catherine Mahony, Jorge Naciff

Regul Toxicol Pharmacol· June 2011

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Predicting developmental toxicity through toxicogenomics.
George P Daston, Jorge M Naciff

Birth Defects Res C Embryo Today· June 2010

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The genomic response of Ishikawa cells to bisphenol A exposure is dose- and time-dependent.
Jorge M Naciff, Zubin S Khambatta, Timothy D Reichling, Gregory J Carr, Jay P Tiesman

Toxicology· April 2010

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The genomic response of a human uterine endometrial adenocarcinoma cell line to 17alpha-ethynyl estradiol.
Jorge M Naciff, Zubin S Khambatta, Ryan G Thomason, Gregory J Carr, Jay P Tiesman

Toxicol Sci· January 2009

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Uterine temporal response to acute exposure to 17alpha-ethinyl estradiol in the immature rat.
Jorge M Naciff, Gary J Overmann, Suzanne M Torontali, Gregory J Carr, Zubin S Khambatta

Toxicol Sci· June 2007

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Design of a microsphere-based high-throughput gene expression assay to determine estrogenic potential.
Jorge M Naciff, Brian D Richardson, Kerry G Oliver, M Lynn Jump, Suzanne M Torontali

Environ Health Perspect· September 2005

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Gene expression changes induced in the testis by transplacental exposure to high and low doses of 17{alpha}-ethynyl estradiol, genistein, or bisphenol A.
Jorge M Naciff, Karla A Hess, Gary J Overmann, Suzanne M Torontali, Gregory J Carr

Toxicol Sci· August 2005

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Gene expression changes related to growth and differentiation in the fetal and juvenile reproductive system of the female rat: evaluation of microarray results.
George P Daston, Jorge M Naciff

Reprod Toxicol· June 2005

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Evaluation of the gene expression changes induced by 17-alpha-ethynyl estradiol in the immature uterus/ovaries of the rat using high density oligonucleotide arrays.
Jorge M Naciff, Suzanne M Torontali, Gary I Overmann, Gregory J Carr, Jay P Tiesman

Birth Defects Res B Dev Reprod Toxicol· April 2005

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