Publications by authors named "Eric Hack"

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Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Gladys Ouedraogo, Camilla Alexander-White, Dagmar Bury, Harvey J Clewell, Mark Cronin, Eric Hack

Regul Toxicol Pharmacol· July 2022

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A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment.
Camilla Alexander-White, Dagmar Bury, Mark Cronin, Matthew Dent, Eric Hack

Regul Toxicol Pharmacol· March 2022

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New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Dagmar Bury, Camilla Alexander-White, Harvey J Clewell, Mark Cronin, Bertrand Desprez, Eric Hack

Regul Toxicol Pharmacol· July 2021

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Internal Threshold of Toxicological Concern (iTTC): Where We Are Today and What Is Possible in the Near Future.
Corie A Ellison, Anne Marie Api, Richard A Becker, Alina Y Efremenko, Sanket Gadhia, C Eric Hack

Front Toxicol· January 2021

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PBPK model reporting template for chemical risk assessment applications.
Yu-Mei Tan, Melissa Chan, Amechi Chukwudebe, Jeanne Domoradzki, Jeffrey Fisher, C Eric Hack

Regul Toxicol Pharmacol· August 2020

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An evaluation of the USEPA Proposed Approaches for applying a biologically based dose-response model in a risk assessment for perchlorate in drinking water.
Harvey J Clewell, P Robinan Gentry, C Eric Hack, Tracy Greene, Rebecca A Clewell

Regul Toxicol Pharmacol· April 2019

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Lipid, water, and protein composition to facilitate kinetic modeling of the auditory pathway.
Nadja Grobe, Latha Narayanan, Dominique N Brown, Sarah T Law, Isaie Sibomana, C Eric Hack

Toxicol Mech Methods· January 2019

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Development of Recombinant Proteins to Treat Chronic Pain.
Judith Prado, Jelena Popov-Celeketic, Cristine Steen-Louws, Ramin Raoof, Eric Hack

J Vis Exp· April 2018

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Predicting passive and active tissue:plasma partition coefficients: interindividual and interspecies variability.
Christopher D Ruark, C Eric Hack, Peter J Robinson, Deirdre A Mahle, Jeffery M Gearhart

J Pharm Sci· July 2014

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Quantitative structure-activity relationships for organophosphates binding to acetylcholinesterase.
Christopher D Ruark, C Eric Hack, Peter J Robinson, Paul E Anderson, Jeffery M Gearhart

Arch Toxicol· February 2013

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Quantitative structure-activity relationships for organophosphates binding to trypsin and chymotrypsin.
Christopher D Ruark, C Eric Hack, Peter J Robinson, Jeffery M Gearhart

J Toxicol Environ Health A· December 2010

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A Bayesian network model for biomarker-based dose response.
C Eric Hack, Lynne T Haber, Andrew Maier, Paul Shulte, Bruce Fowler

Risk Anal· July 2010

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Use of Markov Chain Monte Carlo analysis with a physiologically-based pharmacokinetic model of methylmercury to estimate exposures in US women of childbearing age.
Bruce C Allen, C Eric Hack, Harvey J Clewell

Risk Anal· August 2007

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A pharmacokinetic model of the intracellular dosimetry of inhaled nickel.
C Eric Hack, Tammie R Covington, Greg Lawrence, Annette M Shipp, Robinan Gentry

J Toxicol Environ Health A· March 2007

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Observations on complement activity in the two-stage inflammatory/hemostatic response in the baboon and human models of E. coli sepsis and endotoxemia.
Fletcher B Taylor, Eric Hack, Florea Lupu

Adv Exp Med Biol· February 2007

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Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
C Eric Hack, Weihsueh A Chiu, Q Jay Zhao, Harvey J Clewell

Regul Toxicol Pharmacol· October 2006

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Revised assessment of cancer risk to dichloromethane: part I Bayesian PBPK and dose-response modeling in mice.
Dale J Marino, Harvey J Clewell, P Robinan Gentry, Tammie R Covington, C Eric Hack

Regul Toxicol Pharmacol· June 2006

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Bayesian analysis of physiologically based toxicokinetic and toxicodynamic models.
C Eric Hack

Toxicology· April 2006

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Dose-response and risk assessment of airborne hexavalent chromium and lung cancer mortality.
Casey Crump, Kenny Crump, Eric Hack, Rose Luippold, Kenneth Mundt

Risk Anal· December 2003

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An approach for the quantitative consideration of genetic polymorphism data in chemical risk assessment: examples with warfarin and parathion.
P Robinan Gentry, C Eric Hack, Lynne Haber, Andrew Maier, Harvey J Clewell

Toxicol Sci· November 2002

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