Publications by authors named "Joseph Brunner"

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Probing Hydrodynamic Fluctuation-Induced Forces with an Oscillating Robot.
Steven W Tarr, Joseph S Brunner, Daniel Soto, Daniel I Goldman

Phys Rev Lett· February 2024

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Investigation of orexin-2 selective receptor antagonists: Structural modifications resulting in dual orexin receptor antagonists.
Jason W Skudlarek, Christina N DiMarco, Kerim Babaoglu, Anthony J Roecker, Joseph G Bruno, Joseph Brunner

Bioorg Med Chem Lett· March 2017

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Identification of MK-8133: An orexin-2 selective receptor antagonist with favorable development properties.
Scott D Kuduk, Jason W Skudlarek, Christina N DiMarco, Joseph G Bruno, Mark H Pausch, Joseph Brunner

Bioorg Med Chem Lett· June 2015

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Synthesis and evaluation of carbon-linked analogs of dual orexin receptor antagonist filorexant.
Scott D Kuduk, Jason W Skudlarek, Christina N Di Marco, Joseph G Bruno, Mark A Pausch, Joseph Brunner

Bioorg Med Chem Lett· April 2014

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Dual orexin receptor antagonists show distinct effects on locomotor performance, ethanol interaction and sleep architecture relative to gamma-aminobutyric acid-A receptor modulators.
Andres D Ramirez, Anthony L Gotter, Steven V Fox, Pamela L Tannenbaum, Lihang Yao, Joseph Brunner

Front Neurosci· January 2014

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Quantitative electroencephalography within sleep/wake states differentiates GABAA modulators eszopiclone and zolpidem from dual orexin receptor antagonists in rats.
Steven V Fox, Anthony L Gotter, Spencer J Tye, Susan L Garson, Alan T Savitz, Joseph I Brunner

Neuropsychopharmacology· November 2013

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The duration of sleep promoting efficacy by dual orexin receptor antagonists is dependent upon receptor occupancy threshold.
Anthony L Gotter, Christopher J Winrow, Joseph Brunner, Susan L Garson, Steven V Fox

BMC Neurosci· August 2013

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Orexin receptor antagonists differ from standard sleep drugs by promoting sleep at doses that do not disrupt cognition.
Jason M Uslaner, Spencer J Tye, Donnie M Eddins, Xiaohai Wang, Steven V Fox, Joseph Brunner

Sci Transl Med· April 2013

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Altered sleep and affect in the neurotensin receptor 1 knockout mouse.
Karrie Fitzpatrick, Christopher J Winrow, Anthony L Gotter, Joshua Millstein, Janna Arbuzova, Joseph Brunner

Sleep· July 2012

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Pharmacological validation of candidate causal sleep genes identified in an N2 cross.
Joseph I Brunner, Anthony L Gotter, Joshua Millstein, Susan Garson, Jacquelyn Binns

J Neurogenet· December 2011

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TASK-3 as a potential antidepressant target.
Anthony L Gotter, Vincent P Santarelli, Scott M Doran, Pamela L Tannenbaum, Richard L Kraus, Joseph I Brunner

Brain Res· October 2011

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Ligand crowding at a nascent signal sequence.
Gottfried Eisner, Hans-Georg Koch, Konstanze Beck, Joseph Brunner, Matthias Muller

J Cell Biol· October 2003

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Differential interactions between a twin-arginine signal peptide and its translocase in Escherichia coli.
Meriem Alami, Iris Lüke, Sandra Deitermann, Gottfried Eisner, Hans-Georg Koch, Joseph Brunner

Mol Cell· October 2003

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Interplay of signal recognition particle and trigger factor at L23 near the nascent chain exit site on the Escherichia coli ribosome.
Ronald S Ullers, Edith N G Houben, Amanda Raine, Corinne M ten Hagen-Jongman, Måns Ehrenberg, Joseph Brunner

J Cell Biol· May 2003

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