Publications by authors named "Joseph D Racca"

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Role of nucleobase-specific interactions in the binding and bending of DNA by human male sex determination factor SRY.
Joseph D Racca, Yen-Shan Chen, Adam R Brabender, Umberto Battistin, Michael A Weiss

J Biol Chem· September 2024

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Tenuous transcriptional threshold of human sex determination. II. SRY exploits water-mediated clamp at the edge of ambiguity.
Joseph D Racca, Deepak Chatterjee, Yen-Shan Chen, Ratan K Rai, Yanwu Yang

Front Endocrinol (Lausanne)· January 2023

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Tenuous Transcriptional Threshold of Human Sex Determination. I. SRY and Swyer Syndrome at the Edge of Ambiguity.
Yen-Shan Chen, Joseph D Racca, Michael A Weiss

Front Endocrinol (Lausanne)· August 2022

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Human Sex Determination at the Edge of Ambiguity: INHERITED XY SEX REVERSAL DUE TO ENHANCED UBIQUITINATION AND PROTEASOMAL DEGRADATION OF A MASTER TRANSCRIPTION FACTOR.
Joseph D Racca, Yen-Shan Chen, Yanwu Yang, Nelson B Phillips, Michael A Weiss

J Biol Chem· October 2016

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Structure-function relationships in human testis-determining factor SRY: an aromatic buttress underlies the specific DNA-bending surface of a high mobility group (HMG) box.
Joseph D Racca, Yen-Shan Chen, James D Maloy, Nalinda Wickramasinghe, Nelson B Phillips

J Biol Chem· November 2014

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Inherited human sex reversal due to impaired nucleocytoplasmic trafficking of SRY defines a male transcriptional threshold.
Yen-Shan Chen, Joseph D Racca, Nelson B Phillips, Michael A Weiss

Proc Natl Acad Sci U S A· September 2013

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Microsatellite-encoded domain in rodent Sry functions as a genetic capacitor to enable the rapid evolution of biological novelty.
Yen-Shan Chen, Joseph D Racca, Paul W Sequeira, Nelson B Phillips, Michael A Weiss

Proc Natl Acad Sci U S A· August 2013

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