Publications by authors named "Joseph Promes"

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Perilipin 2 downregulation in β cells impairs insulin secretion under nutritional stress and damages mitochondria.
Akansha Mishra, Siming Liu, Joseph Promes, Mikako Harata, William Sivitz

JCI Insight· May 2021

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Genetic deletion of miR-204 improves glycemic control despite obesity in db/db mice.
Ravinder Reddy Gaddam, Young-Rae Kim, Quixia Li, Julia S Jacobs, Mohanad Gabani, Joseph A Promes

Biochem Biophys Res Commun· November 2020

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Adipose Triglyceride Lipase Is a Key Lipase for the Mobilization of Lipid Droplets in Human β-Cells and Critical for the Maintenance of Syntaxin 1a Levels in β-Cells.
Siming Liu, Joseph A Promes, Mikako Harata, Akansha Mishra, Samuel B Stephens

Diabetes· June 2020

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Adipose Triglyceride Lipase is a Key Lipase for the Mobilization of Lipid Droplets in Human Beta Cells and Critical for the Maintenance of Syntaxin1a Level in Beta Cells.
Siming Liu, Joseph A Promes, Mikako Harata, Akansha Mishra, Samuel B Stephens

Diabetes· March 2020

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Connecting pancreatic islet lipid metabolism with insulin secretion and the development of type 2 diabetes.
Yumi Imai, Ryan S Cousins, Siming Liu, Brian M Phelps, Joseph A Promes

Ann N Y Acad Sci· February 2020

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Lentiviral Mediated Gene Silencing in Human Pseudoislet Prepared in Low Attachment Plates.
Siming Liu, Mikako Harata, Joseph A Promes, Anthony J Burand, James A Ankrum

J Vis Exp· May 2019

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Delivery of shRNA via lentivirus in human pseudoislets provides a model to test dynamic regulation of insulin secretion and gene function in human islets.
Mikako Harata, Siming Liu, Joseph A Promes, Anthony J Burand, James A Ankrum

Physiol Rep· October 2018

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Effect of a mitochondrial-targeted coenzyme Q analog on pancreatic β-cell function and energetics in high fat fed obese mice.
Yumi Imai, Brian D Fink, Joseph A Promes, Chaitanya A Kulkarni, Robert J Kerns

Pharmacol Res Perspect· June 2018

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