Publications by authors named "Joseph R Polli"

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Beyond MABEL: An Integrative Approach to First in Human Dose Selection of Immunomodulators by the Health and Environmental Sciences Institute (HESI) Immuno-Safety Technical Committee (ITC).
Mineo Matsumoto, Joseph Ryan Polli, Suresh K Swaminathan, Kaushik Datta, Cris Kamperschroer

Clin Pharmacol Ther· September 2024

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Payload-Binding Fab Fragments Increase the Therapeutic Index of MMAE Antibody-Drug Conjugates.
Brandon M Bordeau, Toan Duc Nguyen, Joseph Ryan Polli, Ping Chen, Joseph P Balthasar

Mol Cancer Ther· April 2023

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Cell Penetrating Peptides Conjugated to Anti-Carcinoembryonic Antigen "Catch-and-Release" Monoclonal Antibodies Alter Plasma and Tissue Pharmacokinetics in Colorectal Cancer Xenograft Mice.
Joseph Ryan Polli, Joseph P Balthasar

Bioconjug Chem· August 2022

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Targeted Delivery of Endosomal Escape Peptides to Enhance Immunotoxin Potency and Anti-cancer Efficacy.
Joseph Ryan Polli, Ping Chen, Brandon M Bordeau, Joseph P Balthasar

AAPS J· March 2022

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Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Prediction of Monoclonal Antibody Tumor Disposition.
Brandon M Bordeau, Joseph Ryan Polli, Ferdinand Schweser, Hans Peter Grimm, Wolfgang F Richter

Int J Mol Sci· January 2022

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Detection of Caenorhabditis elegans Germ Cell Apoptosis Following Exposure to Environmental Contaminant Mixtures: A Crude Oil-Dispersant Mixture Example.
Joseph Ryan Polli, Mary Farwell, Xiaoping Pan

Methods Mol Biol· August 2021

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Quantitative analysis of PAH compounds in DWH crude oil and their effects on Caenorhabditis elegans germ cell apoptosis, associated with CYP450s upregulation.
Joseph R Polli, Blake R Rushing, Luke Lish, Leia Lewis, Mustafa I Selim

Sci Total Environ· November 2020

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High-Throughput, Sensitive LC-MS Quantification of Biotherapeutics and Biomarkers Using Antibody-Free, Peptide-Level, Multiple-Mechanism Enrichment via Strategic Regulation of pH and Ionic and Solvent Strengths.
Bo An, Ming Zhang, Jie Pu, Shichen Shen, Yang Qu, Joseph Ryan Polli

Anal Chem· March 2019

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Physiologically Based Modeling of the Pharmacokinetics of "Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibodies in Colorectal Cancer Xenograft Mouse Models.
Joseph Ryan Polli, Frank A Engler, Joseph P Balthasar

J Pharm Sci· January 2019

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"Catch-and-Release" Anti-Carcinoembryonic Antigen Monoclonal Antibody Leads to Greater Plasma and Tumor Exposure in a Mouse Model of Colorectal Cancer.
Frank A Engler, Joseph Ryan Polli, Tommy Li, Bo An, Michael Otteneder

J Pharmacol Exp Ther· July 2018

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Triclosan Disrupts SKN-1/Nrf2-Mediated Oxidative Stress Response in C. elegans and Human Mesenchymal Stem Cells.
Dong Suk Yoon, Yoorim Choi, Dong Seok Cha, Peng Zhang, Seong Mi Choi, Joseph Ryan Polli

Sci Rep· October 2017

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From the Cover: ZnO Nanoparticles Enhanced Germ Cell Apoptosis in Caenorhabditis elegans, in Comparison with ZnCl2.
Brittany O'Donnell, Lily Huo, Joseph R Polli, Li Qiu, David N Collier

Toxicol Sci· April 2017

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Drug-dependent behaviors and nicotinic acetylcholine receptor expressions in Caenorhabditis elegans following chronic nicotine exposure.
Joseph R Polli, Dorothy L Dobbins, Robert A Kobet, Mary A Farwell, Baohong Zhang

Neurotoxicology· March 2015

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Dispersed crude oil amplifies germ cell apoptosis in Caenorhabditis elegans, followed a CEP-1-dependent pathway.
Joseph Ryan Polli, Yanqiong Zhang, Xiaoping Pan

Arch Toxicol· March 2014

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Impacts of chronic low-level nicotine exposure on Caenorhabditis elegans reproduction: identification of novel gene targets.
Michael A Smith, Yanqiong Zhang, Joseph R Polli, Hongmei Wu, Baohong Zhang

Reprod Toxicol· September 2013

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Chemical dispersant potentiates crude oil impacts on growth, reproduction, and gene expression in Caenorhabditis elegans.
Yanqiong Zhang, Dongliang Chen, Adrien C Ennis, Joseph R Polli, Peng Xiao

Arch Toxicol· February 2013

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