Publications by authors named "Joseph W Gunnet"

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Pharmacological characterization of RWJ-676070, a dual vasopressin V(1A)/V(2) receptor antagonist.
Joseph W Gunnet, Pamela Wines, Min Xiang, Philip Rybczynski, Patricia Andrade-Gordon

Eur J Pharmacol· August 2008

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Next-generation spirobenzazepines: identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies.
Min Amy Xiang, Philip J Rybczynski, Mona Patel, Robert H Chen, David F McComsey, Joseph W Gunnet

Bioorg Med Chem Lett· December 2007

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Synthesis and SAR of 1,3-disubstituted cyclohexylmethyl urea and amide derivatives as non-peptidic motilin receptor antagonists.
Sigmond G Johnson, Joseph W Gunnet, John B Moore, William Miller, Pam Wines

Bioorg Med Chem Lett· July 2006

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Enhancement of arachidonic acid signaling pathway by nicotinic acid receptor HM74A.
Yuting Tang, Lubing Zhou, Joseph W Gunnet, Pamela G Wines, Ellen V Cryan

Biochem Biophys Res Commun· June 2006

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Characterization of RWJ-351647, a novel nonpeptide vasopressin V2 receptor antagonist.
Joseph W Gunnet, Jay M Matthews, Bruce E Maryanoff, Lawrence de Garavilla, Patricia Andrade-Gordon

Clin Exp Pharmacol Physiol· April 2006

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Sustained aquaretic effect of the V2-AVP receptor antagonist, RWJ-351647, in cirrhotic rats with ascites and water retention.
Josefa Ros, Guillermo Fernández-Varo, Javier Muñoz-Luque, Vicente Arroyo, Juan Rodés, Joseph W Gunnet

Br J Pharmacol· November 2005

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Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates.
Jay M Matthews, William J Hoekstra, Alexey B Dyatkin, Leonard R Hecker, Dennis J Hlasta, Joseph W Gunnet

Bioorg Med Chem Lett· June 2004

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Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists.
Jay M Matthews, Michael N Greco, Leonard R Hecker, William J Hoekstra, Patricia Andrade-Gordon, Joseph W Gunnet

Bioorg Med Chem Lett· February 2003

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Bridged bicyclic vasopressin receptor antagonists with V(2)-selective or dual V(1a)/V(2) activity.
Alexey B Dyatkin, William J Hoekstra, Dennis J Hlasta, Patricia Andrade-Gordon, Lawrence de Garavilla, Joseph W Gunnet

Bioorg Med Chem Lett· November 2002

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