Publications by authors named "Philip Rybczynski"

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Pharmacological chaperones as therapeutics for lysosomal storage diseases.
Robert E Boyd, Gary Lee, Philip Rybczynski, Elfrida R Benjamin, Richie Khanna

J Med Chem· April 2013

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Improvement of dyslipidemia, insulin sensitivity, and energy balance by a peroxisome proliferator-activated receptor alpha agonist.
Xiaoli Chen, Jay Matthews, Lubing Zhou, Patricia Pelton, Yin Liang, Philip Rybczynski

Metabolism· November 2008

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Pharmacological characterization of RWJ-676070, a dual vasopressin V(1A)/V(2) receptor antagonist.
Joseph W Gunnet, Pamela Wines, Min Xiang, Philip Rybczynski, Patricia Andrade-Gordon

Eur J Pharmacol· August 2008

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Next-generation spirobenzazepines: identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies.
Min Amy Xiang, Philip J Rybczynski, Mona Patel, Robert H Chen, David F McComsey

Bioorg Med Chem Lett· December 2007

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Design and synthesis of indane-ureido-thioisobutyric acids: A novel class of PPARalpha agonists.
Jay M Matthews, Xiaoli Chen, Ellen Cryan, Dennis J Hlasta, Philip J Rybczynski

Bioorg Med Chem Lett· December 2007

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Indole-glucosides as novel sodium glucose co-transporter 2 (SGLT2) inhibitors. Part 2.
Xiaoyan Zhang, Maud Urbanski, Mona Patel, Geoffrey G Cox, Roxanne E Zeck, Philip J Rybczynski

Bioorg Med Chem Lett· March 2006

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Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1.
Xiaoyan Zhang, Maud Urbanski, Mona Patel, Roxanne E Zeck, Geoffrey G Cox, Philip J Rybczynski

Bioorg Med Chem Lett· December 2005

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Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.
Joseph Dudash, Yongzheng Zhang, John B Moore, Richard Look, Yin Liang, Philip J Rybczynski

Bioorg Med Chem Lett· November 2005

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Glycosylated dihydrochalcones as potent and selective sodium glucose co-transporter 2 (SGLT2) inhibitors.
Joseph Dudash, Xiaoyan Zhang, Roxanne E Zeck, Sigmond G Johnson, Geoffrey G Cox, Philip J Rybczynski

Bioorg Med Chem Lett· October 2004

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Synthesis and evaluation of nonpeptide substituted spirobenzazepines as potent vasopressin antagonists.
Min Amy Xiang, Robert H Chen, Keith T Demarest, Joseph Gunnet, Richard Look, Philip J Rybczynski

Bioorg Med Chem Lett· June 2004

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Benzoxazinones as PPARgamma agonists. 2. SAR of the amide substituent and in vivo results in a type 2 diabetes model.
Philip J Rybczynski, Roxanne E Zeck, Joseph Dudash, Donald W Combs, Thomas P Burris

J Med Chem· January 2004

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2,5-disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists.
Maud J Urbanski, Robert H Chen, Keith T Demarest, Joseph Gunnet, Richard Look, Philip J Rybczynski

Bioorg Med Chem Lett· November 2003

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Benzoxazinones as PPARgamma agonists. part 1: SAR of three aromatic regions.
Philip J Rybczynski, Roxanne E Zeck, Donald W Combs, Ignatius Turchi, Thomas P Burris

Bioorg Med Chem Lett· July 2003

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Hepatic biotransformation of the new calcium-mimetic agent, RWJ-68025, in the rat and in man--API-MS/MS identification of metabolites.
Wu-Nan Wu, Linda A McKown, Philip J Rybczynski, Keith Demarest

J Pharm Pharmacol· May 2003

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Treatment of non-insulin-dependent diabetes mellitus.
Mona Patel, Philip J Rybczynski

Expert Opin Investig Drugs· April 2003

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