Publications by authors named "Richard Look"

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Next-generation spirobenzazepines: identification of RWJ-676070 as a balanced vasopressin V1a/V2 receptor antagonist for human clinical studies.
Min Amy Xiang, Philip J Rybczynski, Mona Patel, Robert H Chen, David F McComsey, Richard Look

Bioorg Med Chem Lett· December 2007

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Characterization of RWJ-351647, a novel nonpeptide vasopressin V2 receptor antagonist.
Joseph W Gunnet, Jay M Matthews, Bruce E Maryanoff, Lawrence de Garavilla, Patricia Andrade-Gordon, Richard Look

Clin Exp Pharmacol Physiol· April 2006

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Synthesis and evaluation of 3-anilino-quinoxalinones as glycogen phosphorylase inhibitors.
Joseph Dudash, Yongzheng Zhang, John B Moore, Richard Look, Yin Liang

Bioorg Med Chem Lett· November 2005

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Potent nonpeptide vasopressin receptor antagonists based on oxazino- and thiazinobenzodiazepine templates.
Jay M Matthews, William J Hoekstra, Alexey B Dyatkin, Leonard R Hecker, Dennis J Hlasta, Richard Look

Bioorg Med Chem Lett· June 2004

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Synthesis and evaluation of spirobenzazepines as potent vasopressin receptor antagonists.
Min Amy Xiang, Robert H Chen, Keith T Demarest, Joseph Gunnet, Richard Look

Bioorg Med Chem Lett· June 2004

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Synthesis and evaluation of nonpeptide substituted spirobenzazepines as potent vasopressin antagonists.
Min Amy Xiang, Robert H Chen, Keith T Demarest, Joseph Gunnet, Richard Look

Bioorg Med Chem Lett· June 2004

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3-(7-Azaindolyl)-4-arylmaleimides as potent, selective inhibitors of glycogen synthase kinase-3.
Han-Cheng Zhang, Hong Ye, Bruce R Conway, Claudia K Derian, Michael F Addo, Richard Look

Bioorg Med Chem Lett· June 2004

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Synthesis and biological evaluation of novel macrocyclic bis-7-azaindolylmaleimides as potent and highly selective glycogen synthase kinase-3 beta (GSK-3 beta) inhibitors.
Lan Shen, Catherine Prouty, Bruce R Conway, Lori Westover, Jun Z Xu, Richard A Look

Bioorg Med Chem· March 2004

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2,5-disubstituted 3,4-dihydro-2H-benzo[b][1,4]thiazepines as potent and selective V2 arginine vasopressin receptor antagonists.
Maud J Urbanski, Robert H Chen, Keith T Demarest, Joseph Gunnet, Richard Look

Bioorg Med Chem Lett· November 2003

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Macrocyclic bisindolylmaleimides as inhibitors of protein kinase C and glycogen synthase kinase-3.
Han-Cheng Zhang, Kimberly B White, Hong Ye, David F McComsey, Claudia K Derian, Richard Look

Bioorg Med Chem Lett· September 2003

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Synthesis and discovery of macrocyclic polyoxygenated bis-7-azaindolylmaleimides as a novel series of potent and highly selective glycogen synthase kinase-3beta inhibitors.
Gee-Hong Kuo, Catherine Prouty, Alan DeAngelis, Lan Shen, David J O'Neill, Richard A Look

J Med Chem· September 2003

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Synthesis and biological evaluation of novel indoloazepine derivatives as non-peptide vasopressin V2 receptor antagonists.
Jay M Matthews, Michael N Greco, Leonard R Hecker, William J Hoekstra, Patricia Andrade-Gordon, Richard Look

Bioorg Med Chem Lett· February 2003

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Bridged bicyclic vasopressin receptor antagonists with V(2)-selective or dual V(1a)/V(2) activity.
Alexey B Dyatkin, William J Hoekstra, Dennis J Hlasta, Patricia Andrade-Gordon, Lawrence de Garavilla, Richard Look

Bioorg Med Chem Lett· November 2002

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