Publications by authors named "Joshua D Chandler"

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People with cystic fibrosis with high sputum neutrophil elastase on elexacaftor-tezacaftor-ivacaftor exhibit worse pulmonary function and pro-inflammatory airway milieu.
Alexandre Cammarata-Mouchtouris, Diego Moncada Giraldo, Genoah L Collins, Maria M Parrilla, Susan O Kim, Joshua D Chandler

Sci Rep· December 2025

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Early life elevations of methionine oxidation and ornithine track and predict cystic fibrosis structural lung disease.
Sarah Mansour, Lisa J M Slimmen, George L Silva, Genoah L Collins, Vincent D Giacalone, Joshua D Chandler

ERJ Open Res· November 2025

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A carnitine transporter at the blood-brain barrier modulates sleep via glial lipid metabolism in .
Ashley Avila, Ava S Lewandowski, Yongjun Li, Jesse Gui, Kaeun A Lee, Joshua D Chandler

Proc Natl Acad Sci U S A· January 2025

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Low-added sugar dietary intervention study to mitigate glucose intolerance and improve body composition in adults with cystic fibrosis: a protocol of a double-blind, randomised study.
Swati Zaveri, Arlene Stecenko, William R Hunt, Amy Goss, Puneet Sharma, Joshua D Chandler

BMJ Open· December 2024

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Chronic hyperglycemia aggravates lung function in a -Tg murine model.
Guiying Cui, Dina A Moustafa, Shilin Zhao, Analia Vazquez Cegla, James T Lyles, Joshua D Chandler

Am J Physiol Lung Cell Mol Physiol· October 2024

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The therapeutic potential of thiocyanate and hypothiocyanous acid against pulmonary infections.
Nuha Milad Ashtiwi, Susan O Kim, Joshua D Chandler, Balázs Rada

Free Radic Biol Med· July 2024

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Key inflammatory markers in bronchoalveolar lavage predict bronchiectasis progression in young children with CF.
Hamed Horati, Camilla Margaroli, Joshua D Chandler, Matthew B Kilgore, Badies Manai

J Cyst Fibros· May 2024

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Nasal airway inflammatory responses and pathogen detection in infants with cystic fibrosis.
Benjamin T Kopp, Sydney E Ross, Dinesh Bojja, Lokesh Guglani, Joshua D Chandler

J Cyst Fibros· March 2024

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Sweat induction using Pilocarpine microneedle patches for sweat testing in healthy adults.
Jonathan Yuxuan Chen, Song Li, George L Silva, Joshua D Chandler, Mark R Prausnitz

J Cyst Fibros· January 2024

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Substrate-dependent metabolomic signatures of myeloperoxidase activity in airway epithelial cells: Implications for early cystic fibrosis lung disease.
Susan O Kim, Joseph P Shapiro, Kirsten A Cottrill, Genoah L Collins, Shivanthan Shanthikumar, Joshua D Chandler

Free Radic Biol Med· September 2023

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Metabolomics identifies disturbances in arginine, phenylalanine, and glycine metabolism as differentiating features of exacerbating atopic asthma in children.
Kirsten A Cottrill, Joshua D Chandler, Seibi Kobara, Susan T Stephenson, Ahmad F Mohammad

J Allergy Clin Immunol Glob· August 2023

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The 'omics of obesity in B-cell acute lymphoblastic leukemia.
Delaney K Geitgey, Miyoung Lee, Kirsten A Cottrill, Maya Jaffe, William Pilcher, Joshua D Chandler

J Natl Cancer Inst Monogr· May 2023

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Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19.
Samuel Druzak, Elizabeth Iffrig, Blaine R Roberts, Tiantian Zhang, Kirby S Fibben, Joshua D Chandler

Nat Commun· April 2023

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Study on the relationship between selenium and cadmium in diseased human lungs.
Matthew Ryan Smith, Xin Hu, Zachery R Jarrell, Xiaojia He, Michael Orr, Joshua D Chandler

Adv Redox Res· April 2023

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Transcriptional reprogramming of infiltrating neutrophils drives lung pathology in severe COVID-19 despite low viral load.
Devon J Eddins, Junkai Yang, Astrid Kosters, Vincent D Giacalone, Ximo Pechuan-Jorge, Joshua D Chandler

Blood Adv· March 2023

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Exacerbation-prone pediatric asthma is associated with arginine, lysine, and methionine pathway alterations.
Kirsten A Cottrill, Susan T Stephenson, Ahmad F Mohammad, Susan O Kim, Nael A McCarty, Joshua D Chandler

J Allergy Clin Immunol· January 2023

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Macrophage PD-1 associates with neutrophilia and reduced bacterial killing in early cystic fibrosis airway disease.
Camilla Margaroli, Hamed Horati, Luke W Garratt, Vincent D Giacalone, Craig Schofield, Joshua D Chandler

J Cyst Fibros· November 2022

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Immunometabolic Analysis of Synovial Fluid from Juvenile Idiopathic Arthritis Patients.
Vincent D Giacalone, Alexandre Cammarata-Mouchtouris, Diego Moncada-Giraldo, Sreekala P V Shenoy, Lori A Ponder, Joshua D Chandler

Immunohorizons· November 2022

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Pilot study of inflammatory biomarkers in matched induced sputum and bronchoalveolar lavage of 2-year-olds with cystic fibrosis.
Vincent D Giacalone, Diego Moncada-Giraldo, Camilla Margaroli, Milton R Brown, George L Silva, Joshua D Chandler

Pediatr Pulmonol· September 2022

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Metabolomics of airways disease in cystic fibrosis.
Joshua D Chandler, Charles R Esther

Curr Opin Pharmacol· August 2022

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Inactivation of SARS-CoV-2 and COVID-19 Patient Samples for Contemporary Immunology and Metabolomics Studies.
Devon J Eddins, Leda C Bassit, Joshua D Chandler, Natalie S Haddad, Kathryn L Musall

Immunohorizons· February 2022

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Dual oxidase 1 promotes antiviral innate immunity.
Demba Sarr, Aaron D Gingerich, Nuha Milad Asthiwi, Faris Almutairi, Giuseppe A Sautto, Joshua D Chandler

Proc Natl Acad Sci U S A· June 2021

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Airway profile of bioactive lipids predicts early progression of lung disease in cystic fibrosis.
Hamed Horati, Hettie M Janssens, Camilla Margaroli, Mieke Veltman, Marta Stolarczyk, Joshua D Chandler

J Cyst Fibros· November 2020

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The thiocyanate analog selenocyanate is a more potent antimicrobial pro-drug that also is selectively detoxified by the host.
Brian J Day, Preston E Bratcher, Joshua D Chandler, Matthew B Kilgore, Elysia Min

Free Radic Biol Med· January 2020

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Transcriptome Analysis Reveals Distinct Responses to Physiologic Toxic Manganese Exposure in Human Neuroblastoma Cells.
Jolyn Fernandes, Joshua D Chandler, Loukia N Lili, Karan Uppal, Xin Hu

Front Genet· July 2019

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