Publications by authors named "Joshua D Graves"

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DNA2 Nuclease Inhibition Confers Synthetic Lethality in Cancers with Mutant p53 and Synergizes with PARP Inhibitors.
Helena Folly-Kossi, Joshua D Graves, Lidija A Wilhelms Garan, Fang-Tsyr Lin, Weei-Chin Lin

Cancer Res Commun· October 2023

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Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
Kang Liu, Joshua D Graves, Fang-Tsyr Lin, Weei-Chin Lin

J Biol Chem· August 2021

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Correction: Overexpression of TopBP1, a canonical ATR/Chk1 activator, paradoxically hinders ATR/Chk1 activation in cancer.
Kang Liu, Joshua D Graves, Fang-Tsyr Lin, Weei-Chin Lin

J Biol Chem· July 2021

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E2F1 sumoylation as a protective cellular mechanism in oxidative stress response.
Joshua D Graves, Yu-Ju Lee, Kang Liu, Gang Li, Fang-Tsyr Lin

Proc Natl Acad Sci U S A· June 2020

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Cell Cycle-Dependent Switch of TopBP1 Functions by Cdk2 and Akt.
Kang Liu, Joshua D Graves, Yu-Ju Lee, Fang-Tsyr Lin, Weei-Chin Lin

Mol Cell Biol· March 2020

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CGRRF1, a growth suppressor, regulates EGFR ubiquitination in breast cancer.
Yu-Ju Lee, Shiuh-Rong Ho, Joshua D Graves, Yang Xiao, Shixia Huang

Breast Cancer Res· December 2019

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Mutant p53 perturbs DNA replication checkpoint control through TopBP1 and Treslin.
Kang Liu, Fang-Tsyr Lin, Joshua D Graves, Yu-Ju Lee, Weei-Chin Lin

Proc Natl Acad Sci U S A· May 2017

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Regulation of E2 promoter binding factor 1 (E2F1) transcriptional activity through a deubiquitinating enzyme, UCH37.
Christina S Mahanic, Varija Budhavarapu, Joshua D Graves, Gang Li, Weei-Chin Lin

J Biol Chem· October 2015

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Akt switches TopBP1 function from checkpoint activation to transcriptional regulation through phosphoserine binding-mediated oligomerization.
Kang Liu, Joshua D Graves, Jessica D Scott, Rongbao Li, Weei-Chin Lin

Mol Cell Biol· December 2013

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