Publications by authors named "Joshua D Webster"

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Author Correction: Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury.
Nobuhiko Kayagaki, Irma B Stowe, Kamela Alegre, Ishan Deshpande, Shuang Wu, Joshua D Webster

Nature· December 2025

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Molecular subtypes of hepatocellular carcinoma linked to liver cell lineages and clinical outcomes of combination immunotherapy.
Yulei Wang, Yinghui Guan, Alexander R Abbas, Yuji Sano, Saket Jain, Joshua D Webster

Cell Rep Med· December 2025

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Author Correction: Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis.
Kim Newton, Katherine E Wickliffe, Debra L Dugger, Allie Maltzman, Merone Roose-Girma, Joshua D Webster

Nature· December 2025

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Author Correction: Activity of caspase-8 determines plasticity between cell death pathways.
Kim Newton, Katherine E Wickliffe, Allie Maltzman, Debra L Dugger, Rohit Reja, Joshua D Webster

Nature· December 2025

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cFLIP suppresses caspase-1- and MLKL-independent perinatal lethality driven by auto-processing impaired caspase-8 D387A.
Kim Newton, Katherine E Wickliffe, Allie Maltzman, Debra L Dugger, Juan Reyes, Joshua D Webster

Cell Death Differ· December 2025

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Discovery of Clinical Candidate GDC-8264, a Novel, Potent and Selective RIP1 Inhibitor for Amelioration of Tissue Damage and the Treatment of Inflammatory Diseases.
Snahel Patel, Huifen Chen, Eugene Varfolomeev, Youngsu Kwon, Sreemathy Ramaswamy, Joshua D Webster

J Med Chem· November 2025

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Reporting guidelines for manuscripts that use artificial intelligence-based automated image analysis in .
Christof A Bertram, Melissa Schutten, Lorenzo Ressel, Katharina Breininger, Joshua D Webster

Vet Pathol· September 2025

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Reviewer-in-training: A mentoring opportunity in the peer review process.
Joshua D Webster, Patricia Pesavento

Vet Pathol· September 2025

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RIP1 inhibition protects retinal ganglion cells in glaucoma models of ocular injury.
Bo Kyoung Kim, Tatiana Goncharov, Sébastien A Archaimbault, Filip Roudnicky, Joshua D Webster

Cell Death Differ· February 2025

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Impairment of DET1 causes neurological defects and lethality in mice and humans.
Ozge Karayel, Allison Soung, Hem Gurung, Alexander F Schubert, Susan Klaeger, Joshua D Webster

Proc Natl Acad Sci U S A· February 2025

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Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade.
Mayra Cruz Tleugabulova, Sandra P Melo, Aaron Wong, Alexander Arlantico, Meizi Liu, Joshua D Webster

Nat Commun· November 2024

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Diffusion tensor MRI is sensitive to fibrotic injury in a mouse model of oxalate-induced chronic kidney disease.
Rohan S Virgincar, Aaron K Wong, Kai H Barck, Joshua D Webster, Jeffrey Hung

Am J Physiol Renal Physiol· August 2024

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ZBP1 and TRIF trigger lethal necroptosis in mice lacking caspase-8 and TNFR1.
Margaret Solon, Nianfeng Ge, Shannon Hambro, Susan Haller, Jian Jiang, Joshua D Webster

Cell Death Differ· May 2024

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N4BP1 coordinates ubiquitin-dependent crosstalk within the IκB kinase family to limit Toll-like receptor signaling and inflammation.
Alexander D Gitlin, Allie Maltzman, Yuzuka Kanno, Klaus Heger, Rohit Reja, Joshua D Webster

Immunity· May 2024

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Caspase cleavage of RIPK3 after Asp is dispensable for mouse embryogenesis.
Kim Newton, Katherine E Wickliffe, Allie Maltzman, Debra L Dugger, Joshua D Webster

Cell Death Differ· February 2024

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Control of Cell Death in Health and Disease.
Nobuhiko Kayagaki, Joshua D Webster, Kim Newton

Annu Rev Pathol· January 2024

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Inhibition of RIP1 improves immune reconstitution and reduces GVHD mortality while preserving graft-versus-leukemia effects.
Mariano Prado-Acosta, Seihwan Jeong, Alberto Utrero-Rico, Tatiana Goncharov, Joshua D Webster

Sci Transl Med· December 2023

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Targeted alveolar regeneration with Frizzled-specific agonists.
Ahmad N Nabhan, Joshua D Webster, Jarret J Adams, Levi Blazer, Christine Everrett

Cell· July 2023

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Inhibiting membrane rupture with NINJ1 antibodies limits tissue injury.
Nobuhiko Kayagaki, Irma B Stowe, Kamela Alegre, Ishan Deshpande, Shuang Wu, Joshua D Webster

Nature· June 2023

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XIAP deletion sensitizes mice to TNF-induced and RIP1-mediated death.
Axel Witt, Tatiana Goncharov, Yujung Michelle Lee, Matthias Kist, Monika Dohse, Joshua D Webster

Cell Death Dis· April 2023

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T cell-dependent bispecific antibodies alter organ-specific endothelial cell-T cell interaction.
Patricia Himmels, Thi Thu Thao Nguyen, Maresa Caunt Mitzner, Alfonso Arrazate, Stacey Yeung, Joshua D Webster

EMBO Rep· March 2023

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Standardized Processing for Formalin-Fixed, Paraffin-Embedded Cell Pellet Immunohistochemistry Controls.
Charles Havnar, Kathy Hotzel, Carmina Espiritu, Amy Lo, Joshua D Webster

J Vis Exp· July 2022

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Reporting guidelines for manuscripts on tumor prognosis.
F Yvonne Schulman, Paola Roccabianca, Giancarlo Avallone, Christof A Bertram, Mark Chalkley, Joshua D Webster

Vet Pathol· May 2022

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Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection.
Giovanni Luchetti, Justin L Roncaioli, Roberto A Chavez, Alexander F Schubert, Eric M Kofoed, Joshua D Webster

Cell Host Microbe· October 2021

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Genetic inactivation of RIP1 kinase activity in rats protects against ischemic brain injury.
Kimberly Stark, Tatiana Goncharov, Eugene Varfolomeev, Luke Xie, Hai Ngu, Joshua D Webster

Cell Death Dis· April 2021

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