Publications by authors named "Joshua L Price"

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Parallel Temperature Replica-Exchange Molecular Dynamics Simulations Capture the Observed Impact of Stapling on Coiled-Coil Conformational Stability.
Joshua L Price

J Phys Chem B· January 2025

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Exploring biocompatible chemistry to create stapled and photoswitchable variants of the antimicrobial peptide aurein 1.2.
Alexandra E Coram, Richard Morewood, Saan Voss, Joshua L Price, Christoph Nitsche

J Pept Sci· April 2024

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Electrostatic origin of a stabilizing synergistic interaction among b-, c-, and f-residues in a trimeric coiled coil.
Nicholas A Dalley, Kimberlee L Stern, Richard R Kitchen, Keegan B Lloyd, Joshua L Price

Pept Sci (Hoboken)· March 2024

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A probabilistic view of protein stability, conformational specificity, and design.
Jacob A Stern, Tyler J Free, Kimberlee L Stern, Spencer Gardiner, Nicholas A Dalley, Joshua L Price

Sci Rep· September 2023

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Structural guidelines for stabilization of α-helical coiled coils PEG stapling.
Qiang Xiao, Zachary B Jones, Samantha C Hatfield, Dallin S Ashton, Nicholas A Dalley, Joshua L Price

RSC Chem Biol· August 2022

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Prerequisites for Stabilizing Long-Range Synergistic Interactions among -, -, and -Residues in Coiled Coils.
Kimberlee L Stern, Nicholas A Dalley, Nathan T McMurray, Wendy M Billings, Taylor J Loftus, Joshua L Price

Biochemistry· March 2022

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PEGylation Increases the Strength of a Nearby NH-π Hydrogen Bond in the WW Domain.
Steven R E Draper, Zachary B Jones, Seth O Earl, Nicholas A Dalley, Dallin S Ashton, Joshua L Price

Biochemistry· July 2021

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Long-range PEG Stapling: Macrocyclization for Increased Protein Conformational Stability and Resistance to Proteolysis.
Qiang Xiao, Dallin S Ashton, Zachary B Jones, Katherine P Thompson, Joshua L Price

RSC Chem Biol· October 2020

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Context-Dependent Stabilizing Interactions among Solvent-Exposed Residues along the Surface of a Trimeric Helix Bundle.
Kimberlee L Stern, Mason S Smith, Wendy M Billings, Taylor J Loftus, Benjamin M Conover, Joshua L Price

Biochemistry· May 2020

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PEGylation near a Patch of Nonpolar Surface Residues Increases the Conformational Stability of the WW Domain.
Steven R E Draper, Dallin S Ashton, Benjamin M Conover, Anthony J Carter, Kimberlee L Stern, Joshua L Price

J Org Chem· February 2020

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Influence of PEGylation on the Strength of Protein Surface Salt Bridges.
Qiang Xiao, Steven R E Draper, Mason S Smith, Nathaniel Brown, Natalie A B Pugmire, Joshua L Price

ACS Chem Biol· July 2019

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Stapling of two PEGylated side chains increases the conformational stability of the WW domain via an entropic effect.
Qiang Xiao, Natalie A Bécar, Nathaniel P Brown, Mason S Smith, Kimberlee L Stern, Joshua L Price

Org Biomol Chem· November 2018

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An Anion-π Interaction Strongly Stabilizes the β-Sheet Protein WW.
Mason S Smith, Eliza E K Lawrence, Wendy M Billings, Kimberlee S Larsen, Natalie A Bécar, Joshua L Price

ACS Chem Biol· October 2017

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Bulky Dehydroamino Acids Enhance Proteolytic Stability and Folding in β-Hairpin Peptides.
Ankur Jalan, David W Kastner, Kei G I Webber, Mason S Smith, Joshua L Price

Org Lett· October 2017

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Polyethylene Glycol Based Changes to β-Sheet Protein Conformational and Proteolytic Stability Depend on Conjugation Strategy and Location.
Steven R E Draper, Paul B Lawrence, Wendy M Billings, Qiang Xiao, Nathaniel P Brown, Joshua L Price

Bioconjug Chem· October 2017

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Enhancing a long-range salt bridge with intermediate aromatic and nonpolar amino acids.
Mason S Smith, Wendy M Billings, Frank G Whitby, McKenzie B Miller, Joshua L Price

Org Biomol Chem· July 2017

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How PEGylation influences protein conformational stability.
Paul B Lawrence, Joshua L Price

Curr Opin Chem Biol· October 2016

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Conjugation Strategy Strongly Impacts the Conformational Stability of a PEG-Protein Conjugate.
Paul B Lawrence, Wendy M Billings, McKenzie B Miller, Brijesh K Pandey, Andrew R Stephens, Joshua L Price

ACS Chem Biol· July 2016

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Cys(i)-Lys(i+3)-Lys(i+4) triad: a general approach for PEG-based stabilization of α-helical proteins.
Brijesh K Pandey, Mason S Smith, Joshua L Price

Biomacromolecules· December 2014

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Criteria for selecting PEGylation sites on proteins for higher thermodynamic and proteolytic stability.
Paul B Lawrence, Yulian Gavrilov, Sam S Matthews, Minnie I Langlois, Dalit Shental-Bechor, Joshua L Price

J Am Chem Soc· December 2014

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Two structural scenarios for protein stabilization by PEG.
Shu-Han Chao, Sam S Matthews, Ryan Paxman, Aleksei Aksimentiev, Martin Gruebele, Joshua L Price

J Phys Chem B· July 2014

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Stabilizing impact of N-glycosylation on the WW domain depends strongly on the Asn-GlcNAc linkage.
Brijesh K Pandey, Sebastian Enck, Joshua L Price

ACS Chem Biol· October 2013

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Structural and energetic basis of carbohydrate-aromatic packing interactions in proteins.
Wentao Chen, Sebastian Enck, Joshua L Price, David L Powers, Evan T Powers

J Am Chem Soc· July 2013

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Impact of site-specific PEGylation on the conformational stability and folding rate of the Pin WW domain depends strongly on PEG oligomer length.
Brijesh K Pandey, Mason S Smith, Chad Torgerson, Paul B Lawrence, Sam S Matthews, Joshua L Price

Bioconjug Chem· May 2013

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N-glycosylation of enhanced aromatic sequons to increase glycoprotein stability.
Joshua L Price, Elizabeth K Culyba, Wentao Chen, Amber N Murray, Sarah R Hanson

Biopolymers· August 2012

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