Publications by authors named "Joshua P Frederick"

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T-cell Responses to Individualized Neoantigen Therapy mRNA-4157 (V940) Alone or in Combination with Pembrolizumab in the Phase 1 KEYNOTE-603 Study.
Justin F Gainor, Manish R Patel, Jeffrey S Weber, Martin Gutierrez, Julie E Bauman, Joshua P Frederick

Cancer Discov· November 2024

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Spatial Mapping and Immunomodulatory Role of the OX40/OX40L Pathway in Human Non-Small Cell Lung Cancer.
Angelo Porciuncula, Micaela Morgado, Richa Gupta, Kostas Syrigos, Robert Meehan, Joshua P Frederick

Clin Cancer Res· November 2021

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Intratumoral IL12 mRNA Therapy Promotes TH1 Transformation of the Tumor Microenvironment.
Susannah L Hewitt, Dyane Bailey, John Zielinski, Ameya Apte, Faith Musenge, Joshua P Frederick

Clin Cancer Res· December 2020

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Durable anticancer immunity from intratumoral administration of IL-23, IL-36γ, and OX40L mRNAs.
Susannah L Hewitt, Ailin Bai, Dyane Bailey, Kana Ichikawa, John Zielinski, Joshua P Frederick

Sci Transl Med· January 2019

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Role for cytoplasmic nucleotide hydrolysis in hepatic function and protein synthesis.
Benjamin H Hudson, Joshua P Frederick, Li Yin Drake, Louis C Megosh, Ryan P Irving

Proc Natl Acad Sci U S A· March 2013

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A role for a lithium-inhibited Golgi nucleotidase in skeletal development and sulfation.
Joshua P Frederick, A Tsahai Tafari, Sheue-Mei Wu, Louis C Megosh, Shean-Tai Chiou

Proc Natl Acad Sci U S A· August 2008

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Roles for inositol polyphosphate kinases in the regulation of nuclear processes and developmental biology.
Andrew M Seeds, Joshua P Frederick, Marco M K Tsui, John D York

Adv Enzyme Regul· November 2007

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An essential role for an inositol polyphosphate multikinase, Ipk2, in mouse embryogenesis and second messenger production.
Joshua P Frederick, Deidre Mattiske, Jessica A Wofford, Louis C Megosh, Li Yin Drake

Proc Natl Acad Sci U S A· June 2005

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Casein kinase Iepsilon plays a functional role in the transforming growth factor-beta signaling pathway.
David S Waddell, Nicole T Liberati, Xing Guo, Joshua P Frederick, Xiao-Fan Wang

J Biol Chem· July 2004

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Transforming growth factor-beta1 inhibition of vascular smooth muscle cell activation is mediated via Smad3.
Mark W Feinberg, Masafumi Watanabe, Maria A Lebedeva, Ana S Depina, Jun-ichi Hanai, Joshua P Frederick

J Biol Chem· April 2004

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Essential role for Smad3 in regulating MCP-1 expression and vascular inflammation.
Mark W Feinberg, Koichi Shimizu, Maria Lebedeva, Richard Haspel, Kiyoshi Takayama, Joshua P Frederick

Circ Res· March 2004

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Transforming growth factor beta-mediated transcriptional repression of c-myc is dependent on direct binding of Smad3 to a novel repressive Smad binding element.
Joshua P Frederick, Nicole T Liberati, David S Waddell, Yigong Shi, Xiao-Fan Wang

Mol Cell Biol· March 2004

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Beta-arrestin 2 mediates endocytosis of type III TGF-beta receptor and down-regulation of its signaling.
Wei Chen, Kellye C Kirkbride, Tam How, Christopher D Nelson, Jinyao Mo, Joshua P Frederick

Science· September 2003

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Smads "freeze" when they ski.
Joshua P Frederick, Xiao-Fan Wang

Structure· December 2002

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Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice.
Jingsong Zhao, Wei Shi, Yan-Ling Wang, Hui Chen, Pablo Bringas, Joshua P Frederick

Am J Physiol Lung Cell Mol Physiol· March 2002

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