Publications by authors named "Judith Skaptason"

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Identification of (R)-(2-Chloro-3-(trifluoromethyl)phenyl)(1-(5-fluoropyridin-2-yl)-4-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methanone (JNJ 54166060), a Small Molecule Antagonist of the P2X7 receptor.
Devin M Swanson, Brad M Savall, Kevin J Coe, Freddy Schoetens, Tatiana Koudriakova, Judith Skaptason

J Med Chem· September 2016

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Prediction of oral pharmacokinetics of cMet kinase inhibitors in humans: physiologically based pharmacokinetic model versus traditional one-compartment model.
Shinji Yamazaki, Judith Skaptason, David Romero, Sylvia Vekich, Hannah M Jones

Drug Metab Dispos· March 2011

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Dihydroxyphenylisoindoline amides as orally bioavailable inhibitors of the heat shock protein 90 (hsp90) molecular chaperone.
Pei-Pei Kung, Buwen Huang, Gang Zhang, Joe Zhongxiang Zhou, Jeff Wang, Judith Skaptason

J Med Chem· January 2010

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Application of stable isotope methodology in the evaluation of the pharmacokinetics of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride in rats.
Shinji Yamazaki, Lisa N Toth, Emi Kimoto, Janice Bower, Judith Skaptason

Drug Metab Dispos· May 2009

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Pharmacokinetic-pharmacodynamic modeling of biomarker response and tumor growth inhibition to an orally available cMet kinase inhibitor in human tumor xenograft mouse models.
Shinji Yamazaki, Judith Skaptason, David Romero, Joseph H Lee, Helen Y Zou

Drug Metab Dispos· July 2008

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Pharmacologic properties of AG-012986, a pan-cyclin-dependent kinase inhibitor with antitumor efficacy.
Cathy Zhang, Karen Lundgren, Zhengming Yan, Maria E Arango, Sharon Price, Judith Skaptason

Mol Cancer Ther· April 2008

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