Publications by authors named "Jules Heuberger"

Claim this Profile

Mentions over time

Mentions by platform

Video Views

569

Total Likes

61

Extended Reach

192,992

Social Features

29
C
Cannabidiol Lacks Direct Effect on Cortical Excitability: A Randomized, Double Blind, Placebo Controlled, 3-Way Crossover Trial.
Andriy A Gorbenko, Catherine M K E de Cuba, Annika A de Goede, Titiaan E Post, Roman Bohoslavsky, Jules A A C Heuberger

Clin Pharmacol Ther· January 2026

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
Low-dose cannabidiol increases plasma concentrations of amitriptyline: A clinical drug-drug interaction study.
Andriy A Gorbenko, Titiaan E Post, Pamela K Strugala, Erica S Klaassen, Linda E Klumpers, Jules A A C Heuberger

Br J Clin Pharmacol· December 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sentinel dosing: A proposed algorithm to guide decision making on which cohorts in early phase clinical pharmacology trials should use this approach.
Jules A A C Heuberger, Perry de Jongh, Ewoud-Jan van Hoogdalem, Wim Tamminga, Pieter de Graeff

Br J Clin Pharmacol· September 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial.
Brittany N Flores, Seungyoon B Yu, Isaac V Cohen, Melania H Fanok, Wei Luan, Jules A A C Heuberger

Nat Commun· August 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
CB Receptor Antagonist Selonabant (ANEB-001) Blocks Acute THC Effects in Healthy Volunteers: A Phase II Randomized Controlled Trial.
Andriy A Gorbenko, Jules A A C Heuberger, Maria Juachon, Erica Klaassen, Michael Tagen

Clin Pharmacol Ther· May 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
TMS and EEG Pharmacodynamic Effects of a Selective Sphingosine-1-Phosphate Subtype 1 Receptor Agonist on Cortical Excitability in Healthy Subjects.
Catherine M K E de Cuba, Annika A de Goede, Erica S Klaassen, Marije E Otto, Robert J Doll, Jules A A C Heuberger

Clin Pharmacol Ther· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Safety, Pharmacokinetics, and Pharmacodynamics of a First-in-Class ClC-1 Inhibitor to Enhance Muscle Excitability: Phase I Randomized Controlled Trial.
Titia Q Ruijs, Catherine M K E de Cuba, Jules A A C Heuberger, John Hutchison, Jane Bold

Clin Pharmacol Ther· March 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The ClC-1 chloride channel inhibitor NMD670 improves skeletal muscle function in rat models and patients with myasthenia gravis.
Martin Skov, Titia Q Ruijs, Thomas S Grønnebæk, Marianne Skals, Anders Riisager, Jules A A C Heuberger

Sci Transl Med· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Administration of oxathridine, a first-in-class histamine-3 receptor partial agonist in healthy male volunteers: Central nervous system depression and pseudo-hallucinations.
Francis M Dijkstra, Rob G J A Zuiker, Jules A A C Heuberger, Kawita M S Kanhai, Marieke De Kam

Br J Clin Pharmacol· January 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A leucine-rich repeat kinase 2 (LRRK2) pathway biomarker characterization study in patients with Parkinson's disease with and without LRRK2 mutations and healthy controls.
Maurits F J M Vissers, Matthew D Troyer, Eva Thijssen, Diana R Pereira, Jules A A C Heuberger

Clin Transl Sci· August 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
L
LRRK2 Inhibition by BIIB122 in Healthy Participants and Patients with Parkinson's Disease.
Danna Jennings, Sarah Huntwork-Rodriguez, Maurits F J M Vissers, Vinay M Daryani, Dolores Diaz, Jules A A C Heuberger

Mov Disord· March 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Muscle velocity recovery cycles as pharmacodynamic biomarker: Effects of mexiletine in a randomized double-blind placebo-controlled cross-over study.
Titia Q Ruijs, Ingrid W Koopmans, Marieke L de Kam, Martijn R Tannemaat, Geert Jan Groeneveld, Jules A A C Heuberger

Clin Transl Sci· December 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effects of Mexiletine and Lacosamide on Nerve Excitability in Healthy Subjects: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study.
Titia Q Ruijs, Ingrid W Koopmans, Marieke L de Kam, Michiel J van Esdonk, Martin Koltzenburg, Jules A A C Heuberger

Clin Pharmacol Ther· November 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Safety, pharmacokinetics and target engagement of novel RIPK1 inhibitor SAR443060 (DNL747) for neurodegenerative disorders: Randomized, placebo-controlled, double-blind phase I/Ib studies in healthy subjects and patients.
Maurits F J M Vissers, Jules A A C Heuberger, Geert Jan Groeneveld, Jerome Oude Nijhuis, Peter Paul De Deyn

Clin Transl Sci· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Acute retigabine-induced effects on myelinated motor axons in amyotrophic lateral sclerosis.
Boudewijn T H M Sleutjes, Diederik J L Stikvoort García, Maria O Kovalchuk, Jules A A C Heuberger, Geert Jan Groeneveld

Pharmacol Res Perspect· August 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double-blind, placebo-controlled, cross-over study.
Titia Q Ruijs, Jules A A C Heuberger, Annika A de Goede, Dimitrios Ziagkos, Marije E Otto

Br J Clin Pharmacol· June 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Dealing with doping. A plea for better science, governance and education.
Jules A A C Heuberger, April Henning, Adam F Cohen, Bengt Kayser

Br J Clin Pharmacol· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Effect of sustained high buprenorphine plasma concentrations on fentanyl-induced respiratory depression: A placebo-controlled crossover study in healthy volunteers and opioid-tolerant patients.
Laurence M Moss, Marijke Hyke Algera, Robert Dobbins, Frank Gray, Stephanie Strafford, Jules A A C Heuberger

PLoS One· February 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
G
Good Clinical Trials by removing defensive interpretation of Good Clinical Practice guidelines.
Jonas M den Heijer, Jules A A C Heuberger, Hemme Hijma, Annelieke C Kruithof, Jeroen van Smeden

Br J Clin Pharmacol· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis.
Daniel Hidalgo, Jacob Bejder, Ramona Pop, Kyle Gellatly, Yung Hwang, Jules A A C Heuberger

Nat Commun· December 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transcranial magnetic stimulation as a translational biomarker for AMPA receptor modulation.
Patricio O'Donnell, Francis M Dijkstra, Ugur Damar, Lei Quanhong, Annika A de Goede, Jules A A C Heuberger

Transl Psychiatry· May 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Tolerance to Opioid-Induced Respiratory Depression in Chronic High-Dose Opioid Users: A Model-Based Comparison With Opioid-Naïve Individuals.
Marijke Hyke Algera, Erik Olofsen, Laurence Moss, Robert L Dobbins, Marieke Niesters, Jules Heuberger

Clin Pharmacol Ther· March 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Targeting for Success: Demonstrating Proof-of-Concept with Mechanistic Early Phase Clinical Pharmacology Studies for Disease-Modification in Neurodegenerative Disorders.
Maurits F J M Vissers, Jules A A C Heuberger, Geert Jan Groeneveld

Int J Mol Sci· February 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Additive effect of erythropoietin use on exercise-induced endothelial activation and hypercoagulability in athletes.
Jules A A C Heuberger, Jelle J Posthuma, Dimitrios Ziagkos, Joris I Rotmans, Johannes M A Daniels

Eur J Appl Physiol· August 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis