Publications by authors named "Julia Gerson"

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Directed evolution of drug-like Aβ conformation-specific antibodies.
Alec A Desai, Matthew D Smith, Jennifer M Zupancic, Emily K Makowski, Yulei Zhang, Julia E Gerson

Front Immunol· October 2025

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Facile generation of drug-like conformational antibodies specific for amyloid fibrils.
Alec A Desai, Jennifer M Zupancic, Hanna Trzeciakiewicz, Julia E Gerson, Kelly N DuBois

Nat Chem Biol· June 2025

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Expanded US mentorship requires accountability.
Xoco Shinbrot, Julia Gerson, Brianne Gutmann, Kiki Ikossi, Lisa Ulmer

Science· October 2023

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Flow cytometric isolation of drug-like conformational antibodies specific for amyloid fibrils.
Alec A Desai, Jennifer M Zupancic, Hanna Trzeciakiewicz, Julia E Gerson, Kelly N DuBois

bioRxiv· July 2023

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Ubiquilin-2 regulates pathological alpha-synuclein.
Stephanie S Sandoval-Pistorius, Julia E Gerson, Nyjerus Liggans, Jaimie H Ryou, Kulin Oak

Sci Rep· January 2023

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Disrupting the Balance of Protein Quality Control Protein UBQLN2 Accelerates Tau Proteinopathy.
Julia E Gerson, Stephanie Sandoval-Pistorius, Jacqueline P Welday, Aleija Rodriguez, Jordan D Gregory

J Neurosci· March 2022

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Rational affinity maturation of anti-amyloid antibodies with high conformational and sequence specificity.
Alec A Desai, Matthew D Smith, Yulei Zhang, Emily K Makowski, Julia E Gerson

J Biol Chem· August 2021

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Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins.
Julia E Gerson, Hunter Linton, Jiazheng Xing, Alexandra B Sutter, Fayth S Kakos

Sci Rep· January 2021

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Modeling UBQLN2-mediated neurodegenerative disease in mice: Shared and divergent properties of wild type and mutant UBQLN2 in phase separation, subcellular localization, altered proteostasis pathways, and selective cytotoxicity.
Lisa M Sharkey, Stephanie S Sandoval-Pistorius, Shannon J Moore, Julia E Gerson, Robert Komlo

Neurobiol Dis· September 2020

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Ubiquilin-2 differentially regulates polyglutamine disease proteins.
Julia E Gerson, Nathaniel Safren, Svetlana Fischer, Ronak Patel, Emily V Crowley

Hum Mol Genet· August 2020

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Nature-inspired design and evolution of anti-amyloid antibodies.
Mark C Julian, Lilia A Rabia, Alec A Desai, Ammar Arsiwala, Julia E Gerson

J Biol Chem· May 2019

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α-Synuclein Oligomers Induce a Unique Toxic Tau Strain.
Diana L Castillo-Carranza, Marcos J Guerrero-Muñoz, Urmi Sengupta, Julia E Gerson, Rakez Kayed

Biol Psychiatry· October 2018

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Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly.
Lisa M Sharkey, Nathaniel Safren, Amit S Pithadia, Julia E Gerson, Mark Dulchavsky

Proc Natl Acad Sci U S A· October 2018

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AAV2-mediated GRP78 Transfer Alleviates Retinal Neuronal Injury by Downregulating ER Stress and Tau Oligomer Formation.
Yonju Ha, Wei Liu, Hua Liu, Shuang Zhu, Fan Xia, Julia E Gerson

Invest Ophthalmol Vis Sci· September 2018

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Tau oligomers mediate α-synuclein toxicity and can be targeted by immunotherapy.
Julia E Gerson, Kathleen M Farmer, Natalie Henson, Diana L Castillo-Carranza, Mariana Carretero Murillo

Mol Neurodegener· March 2018

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Tau Oligomers Associate with Inflammation in the Brain and Retina of Tauopathy Mice and in Neurodegenerative Diseases.
Ashley N Nilson, Kelsey C English, Julia E Gerson, T Barton Whittle, C Nicolas Crain

J Alzheimers Dis· February 2018

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Tau Oligomers as Pathogenic Seeds: Preparation and Propagation In Vitro and In Vivo.
Julia E Gerson, Urmi Sengupta, Rakez Kayed

Methods Mol Biol· January 2018

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Therapeutic Approaches Targeting Pathological Tau Aggregates.
Julia Gerson, Rakez Kayed

Curr Pharm Des· November 2017

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Potential mechanisms and implications for the formation of tau oligomeric strains.
Julia E Gerson, Amrit Mudher, Rakez Kayed

Crit Rev Biochem Mol Biol· June 2017

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Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer's Disease and Related Tauopathies.
Diana L Castillo-Carranza, Ashley N Nilson, Candice E Van Skike, Jordan B Jahrling, Kishan Patel, Julia E Gerson

Aging Dis· May 2017

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Tau Oligomers Derived from Traumatic Brain Injury Cause Cognitive Impairment and Accelerate Onset of Pathology in Htau Mice.
Julia Gerson, Diana L Castillo-Carranza, Urmi Sengupta, Riddhi Bodani, Donald S Prough

J Neurotrauma· November 2016

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Antibody against Small Aggregated Peptide Specifically Recognizes Toxic Aβ-42 Oligomers in Alzheimer's Disease.
Riddhi U Bodani, Urmi Sengupta, Diana L Castillo-Carranza, Marcos J Guerrero-Muñoz, Julia E Gerson

ACS Chem Neurosci· December 2015

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Tau Oligomers: The Toxic Player at Synapses in Alzheimer's Disease.
Marcos J Guerrero-Muñoz, Julia Gerson, Diana L Castillo-Carranza

Front Cell Neurosci· December 2015

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The interrelationship of proteasome impairment and oligomeric intermediates in neurodegeneration.
Jennifer M Deger, Julia E Gerson, Rakez Kayed

Aging Cell· October 2015

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Understanding the cognitive impact of the contraceptive estrogen Ethinyl Estradiol: tonic and cyclic administration impairs memory, and performance correlates with basal forebrain cholinergic system integrity.
Sarah E Mennenga, Julia E Gerson, Stephanie V Koebele, Melissa L Kingston, Candy W S Tsang

Psychoneuroendocrinology· April 2015

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