Publications by authors named "Julian Simon"

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Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action.
Patricia Wu, Francisco Barros-Becker, Roberto Ogelman, Esra D Camci, Tor H Linbo, Julian A Simon

Front Neurol· November 2024

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Multiple mechanisms of aminoglycoside ototoxicity are distinguished by subcellular localization of action.
Patricia Wu, Francisco Barros Becker, Roberto Ogelman, Esra D Camci, Tor H Linbo, Julian A Simon

bioRxiv· July 2024

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An Biomarker to Characterize Ototoxic Compounds and Novel Protective Therapeutics.
Joseph A Bellairs, Van A Redila, Patricia Wu, Ling Tong, Alyssa Webster, Julian A Simon

Front Mol Neurosci· July 2022

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Chloroquine kills hair cells in zebrafish lateral line and murine cochlear cultures: Implications for ototoxicity.
Samantha N Davis, Patricia Wu, Esra D Camci, Julian A Simon, Edwin W Rubel

Hear Res· September 2020

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Long-term tracking demonstrates effectiveness of a partnership-led training program to advance the careers of biomedical researchers from underrepresented groups.
Beti Thompson, Mary A O'Connell, Karen Peterson, Michele Shuster, Marilyn Drennan, Julian A Simon

PLoS One· March 2020

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A potent peptide-steroid conjugate accumulates in cartilage and reverses arthritis without evidence of systemic corticosteroid exposure.
Michelle L Cook Sangar, Emily J Girard, Gene Hopping, Chunfeng Yin, Fiona Pakiam, Julian A Simon

Sci Transl Med· March 2020

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Discovery of Selective SIRT2 Inhibitors as Therapeutic Agents in B-Cell Lymphoma and Other Malignancies.
Sarwat Chowdhury, Smitha Sripathy, Alyssa Webster, Angela Park, Uyen Lao, Julian A Simon

Molecules· January 2020

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The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion.
Vilma Dembitz, Barbara Tomic, Ivan Kodvanj, Julian A Simon, Antonio Bedalov

J Biol Chem· October 2019

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ORC-13661 protects sensory hair cells from aminoglycoside and cisplatin ototoxicity.
Siân R Kitcher, Nerissa K Kirkwood, Esra D Camci, Patricia Wu, Robin M Gibson, Julian A Simon

JCI Insight· August 2019

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Fate plasticity and reprogramming in genetically distinct populations of leucophores.
Victor M Lewis, Lauren M Saunders, Tracy A Larson, Emily J Bain, Samantha L Sturiale, Julian A Simon

Proc Natl Acad Sci U S A· June 2019

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Inhibition of vaccinia virus replication by nitazoxanide.
Sarah E Hickson, Daciana Margineantu, David M Hockenbery, Julian A Simon, Adam P Geballe

Virology· May 2018

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Phenotypic Optimization of Urea-Thiophene Carboxamides To Yield Potent, Well Tolerated, and Orally Active Protective Agents against Aminoglycoside-Induced Hearing Loss.
Sarwat Chowdhury, Kelly N Owens, R Jason Herr, Qin Jiang, Xinchao Chen, Julian A Simon

J Med Chem· January 2018

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FRET in a Synthetic Flavin- and Bilin-binding Protein.
Julian Simon, Aba Losi, Kai-Hong Zhao, Wolfgang Gärtner

Photochem Photobiol· July 2017

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Identification of small molecule inhibitors of cisplatin-induced hair cell death: results of a 10,000 compound screen in the zebrafish lateral line.
Andrew J Thomas, Patricia Wu, David W Raible, Edwin W Rubel, Julian A Simon

Otol Neurotol· March 2015

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The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis.
Jared M Lucas, Cynthia Heinlein, Tom Kim, Susana A Hernandez, Muzdah S Malik, Julian A Simon

Cancer Discov· November 2014

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First characterisation of a CPD-class I photolyase from a UV-resistant extremophile isolated from High-Altitude Andean Lakes.
Virginia Helena Albarracín, Julian Simon, Gopal P Pathak, Lorena Valle, Thierry Douki

Photochem Photobiol Sci· May 2014

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Development of pyrazolone and isoxazol-5-one cambinol analogues as sirtuin inhibitors.
Sumit S Mahajan, Michele Scian, Smitha Sripathy, Jeff Posakony, Uyen Lao, Julian A Simon

J Med Chem· April 2014

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Targeted inhibition of cell-surface serine protease Hepsin blocks prostate cancer bone metastasis.
Xi Tang, Sumit S Mahajan, Liem T Nguyen, François Béliveau, Richard Leduc, Julian A Simon

Oncotarget· March 2014

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Enterocyte-specific inactivation of SIRT1 reduces tumor load in the APC(+/min) mouse model.
Vid Leko, Gemma J Park, Uyen Lao, Julian A Simon, Antonio Bedalov

PLoS One· January 2014

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Spectroscopic and theoretical study on electronically modified chromophores in LOV domains: 8-bromo- and 8-trifluoromethyl-substituted flavins.
Madina Mansurova, Julian Simon, Susanne Salzmann, Christel M Marian, Wolfgang Gärtner

Chembiochem· March 2013

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Functional mechanotransduction is required for cisplatin-induced hair cell death in the zebrafish lateral line.
Andrew J Thomas, Dale W Hailey, Tamara M Stawicki, Patricia Wu, Allison B Coffin, Julian A Simon

J Neurosci· March 2013

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Fish in a Dish: Drug Discovery for Hearing Habilitation.
Robert Esterberg, Allison B Coffin, Henry Ou, Julian A Simon, David W Raible

Drug Discov Today Dis Models· January 2013

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Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.
Anna L Vlasits, Julian A Simon, David W Raible, Edwin W Rubel, Kelly N Owens

Hear Res· December 2012

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Quinoline ring derivatives protect against aminoglycoside-induced hair cell death in the zebrafish lateral line.
Henry C Ou, Sarah Keating, Patricia Wu, Julian A Simon, David W Raible

J Assoc Res Otolaryngol· December 2012

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Non-specific chemical inhibition of the Fanconi anemia pathway sensitizes cancer cells to cisplatin.
Céline Jacquemont, Julian A Simon, Alan D D'Andrea, Toshiyasu Taniguchi

Mol Cancer· April 2012

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