Publications by authors named "Julie Hutt"

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Preclinical safety and biodistribution assessment of Ad-KCNH2-G628S administered via atrial painting in New Zealand white rabbits.
Janet M Benson, Gensheng Wang, Julie A Hutt, Guodong Wu, Stephen M Kaminsky

Basic Clin Pharmacol Toxicol· August 2023

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Scientific and Regulatory Policy Committee Points to Consider: Nonclinical Research and Development of In Vivo Gene Therapy Products, Emphasizing Adeno-Associated Virus Vectors.
Julie A Hutt, Basel T Assaf, Brad Bolon, Joy Cavagnaro, Elizabeth Galbreath

Toxicol Pathol· January 2022

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Opinion on the Use of Animal Models in Nonclinical Safety Assessment: Pros and Cons.
Radhakrishna Sura, Julie Hutt, Sherry Morgan

Toxicol Pathol· July 2021

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Identification of an Attenuated Substrain of SCHU S4 by Phenotypic and Genotypic Analyses.
Julie A Lovchik, Douglas S Reed, Julie A Hutt, Fangfang Xia, Rick L Stevens

Pathogens· May 2021

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Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention.
Carmen S Tellez, Maria A Picchi, Daniel Juri, Kieu Do, Dhimant H Desai, Julie A Hutt

Clin Epigenetics· February 2021

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Erratum: Assessment of toxicity and biodistribution of recombinant AAV8 vector-mediated immunomodulatory gene therapy in mice with Pompe disease.
Gensheng Wang, Sarah P Young, Deeksha Bali, Julie Hutt, Songtao Li

Mol Ther Methods Clin Dev· June 2019

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Scientific and Regulatory Policy Committee Points to Consider: Data Visualization for Clinical and Anatomic Pathologists.
Sean P Troth, Nancy E Everds, William Siska, Brian Knight, Martin Lamb, Julie Hutt

Toxicol Pathol· July 2018

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Preclinical efficacy and safety of KCNH2-G628S gene therapy for postoperative atrial fibrillation.
Zhao Liu, Julie A Hutt, Barur Rajeshkumar, Yoshihiro Azuma, Kailai L Duan

J Thorac Cardiovasc Surg· November 2017

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Muc1 knockout potentiates murine lung carcinogenesis involving an epiregulin-mediated EGFR activation feedback loop.
Xiuling Xu, Wenshu Chen, Shuguang Leng, Mabel T Padilla, Bryanna Saxton, Julie Hutt

Carcinogenesis· June 2017

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The Natural History of Pneumonic Tularemia in Female Fischer 344 Rats after Inhalational Exposure to Aerosolized Francisella tularensis Subspecies tularensis Strain SCHU S4.
Julie A Hutt, Julie A Lovchik, Alexander Dekonenko, Andrew C Hahn, Terry H Wu

Am J Pathol· February 2017

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Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection.
Matthew D Reed, Julie A Wilder, William M Mega, Julie A Hutt, Philip J Kuehl

PLoS One· May 2016

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Safety and biodistribution assessment of sc-rAAV2.5IL-1Ra administered via intra-articular injection in a mono-iodoacetate-induced osteoarthritis rat model.
Gensheng Wang, Christopher H Evans, Janet M Benson, Julie A Hutt, JeanClare Seagrave

Mol Ther Methods Clin Dev· January 2016

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Corrigendum to "Assessment of toxicity and biodistribution of recombinant AAV8 vector-mediated immunomodulatory gene therapy in mice with Pompe disease".
Gensheng Wang, Sarah P Young, Deeksha Bali, Julie Hutt, Songtao Li

Mol Ther Methods Clin Dev· June 2015

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Assessment of toxicity and biodistribution of recombinant AAV8 vector-mediated immunomodulatory gene therapy in mice with Pompe disease.
Gensheng Wang, Sarah P Young, Deeksha Bali, Julie Hutt, Songtao Li

Mol Ther Methods Clin Dev· May 2015

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Lethal factor, but not edema factor, is required to cause fatal anthrax in cynomolgus macaques after pulmonary spore challenge.
Julie A Hutt, Julie A Lovchik, Melissa Drysdale, Robert L Sherwood, Trevor Brasel

Am J Pathol· December 2014

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Local and systemic tolerability of a 2'O-methoxyethyl antisense oligonucleotide targeting interleukin-4 receptor-α delivery by inhalation in mouse and monkey.
Robert A Fey, Michael V Templin, Jacob D McDonald, Rosie Z Yu, Julie A Hutt

Inhal Toxicol· July 2014

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HIV gp120 induces mucus formation in human bronchial epithelial cells through CXCR4/α7-nicotinic acetylcholine receptors.
Sravanthi Gundavarapu, Neerad C Mishra, Shashi P Singh, Raymond J Langley, Ali Imran Saeed, Julie Hutt

PLoS One· June 2014

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Intrapleural administration of an AAVrh.10 vector coding for human α1-antitrypsin for the treatment of α1-antitrypsin deficiency.
Maria J Chiuchiolo, Stephen M Kaminsky, Dolan Sondhi, Neil R Hackett, Jonathan B Rosenberg, Julie A Hutt

Hum Gene Ther Clin Dev· December 2013

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Gestational exposure of mice to secondhand cigarette smoke causes bronchopulmonary dysplasia blocked by the nicotinic receptor antagonist mecamylamine.
Shashi P Singh, Sravanthi Gundavarapu, Kevin R Smith, Hitendra S Chand, Ali Imran Saeed, Julie Hutt

Environ Health Perspect· August 2013

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Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation.
Eliseo F Castillo, Alexander Dekonenko, John Arko-Mensah, Michael A Mandell, Nicolas Dupont, Julie Hutt

Proc Natl Acad Sci U S A· November 2012

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Expression of either lethal toxin or edema toxin by Bacillus anthracis is sufficient for virulence in a rabbit model of inhalational anthrax.
Julie A Lovchik, Melissa Drysdale, Theresa M Koehler, Julie A Hutt, C Rick Lyons

Infect Immun· July 2012

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Antibodies contribute to effective vaccination against respiratory infection by type A Francisella tularensis strains.
Gopi Mara-Koosham, Julie A Hutt, C Rick Lyons, Terry H Wu

Infect Immun· April 2011

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Cowpox virus inhibits human dendritic cell immune function by nonlethal, nonproductive infection.
Spencer J Hansen, John Rushton, Alexander Dekonenko, Hitendra S Chand, Gwyneth K Olson, Julie A Hutt

Virology· April 2011

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Preclinical evaluation of a recombinant adeno-associated virus vector expressing human alpha-1 antitrypsin made using a recombinant herpes simplex virus production method.
Jeffrey D Chulay, Guo-Jie Ye, Darby L Thomas, David R Knop, Janet M Benson, Julie A Hutt

Hum Gene Ther· February 2011

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Granuloma formation induced by low-dose chronic silica inhalation is associated with an anti-apoptotic response in Lewis rats.
Raymond J Langley, Neerad C Mishra, Juan Carlos Peña-Philippides, Julie A Hutt, Mohan L Sopori

J Toxicol Environ Health A· April 2010

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