Publications by authors named "Julie M Locke"

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N-alkylated isatins evade P-gp mediated efflux and retain potency in MDR cancer cell lines.
Kara L Vine, Lisa Belfiore, Luke Jones, Julie M Locke, Samantha Wade

Heliyon· January 2016

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The antiangiogenic properties of sulfated β-cyclodextrins in anticancer formulations incorporating 5-fluorouracil.
Clare A Watson, Kara L Vine, Julie M Locke, Anna Bezos, Christopher R Parish

Anticancer Drugs· August 2013

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Anti-cancer activity of an acid-labile N-alkylisatin conjugate targeting the transferrin receptor.
Vineesh Indira Chandran, Lidia Matesic, Julie M Locke, Danielle Skropeta, Marie Ranson

Cancer Lett· March 2012

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Synthesis and hydrolytic evaluation of acid-labile imine-linked cytotoxic isatin model systems.
Lidia Matesic, Julie M Locke, Kara L Vine, Marie Ranson, John B Bremner

Bioorg Med Chem· March 2011

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Preclinical evaluation of novel, all-in-one formulations of 5-fluorouracil and folinic acid with reduced toxicity profiles.
Tamantha K Stutchbury, Kara L Vine, Julie M Locke, Jeremy S Chrisp, John B Bremner

Anticancer Drugs· January 2011

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Selective targeting of 2'-deoxy-5-fluorouridine to urokinase positive malignant cells in vitro.
Kara L Vine, Julie M Locke, John B Bremner, Stephen G Pyne, Marie Ranson

Bioorg Med Chem Lett· May 2010

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Development and assessment of novel all-in-one parenteral formulations with integrated anticoagulant properties for the concomitant delivery of 5-fluorouracil and calcium folinate.
Julie M Locke, Tamantha K Stutchbury, Kara L Vine, Allan B Gamble, Philip R Clingan

Anticancer Drugs· October 2009

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N-phenethyl and N-naphthylmethyl isatins and analogues as in vitro cytotoxic agents.
Lidia Matesic, Julie M Locke, John B Bremner, Stephen G Pyne, Danielle Skropeta

Bioorg Med Chem· March 2008

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An investigation into the cytotoxicity and mode of action of some novel N-alkyl-substituted isatins.
Kara L Vine, Julie M Locke, Marie Ranson, Stephen G Pyne, John B Bremner

J Med Chem· October 2007

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Probing molecular shape. 1. Conformational studies of 5-hydroxyhexahydropyrimidine and related compounds.
Julie M Locke, Robyn L Crumbie, Renate Griffith, Trevor D Bailey, Susan Boyd

J Org Chem· May 2007

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In vitro cytotoxicity evaluation of some substituted isatin derivatives.
Kara L Vine, Julie M Locke, Marie Ranson, Kirsten Benkendorff, Stephen G Pyne

Bioorg Med Chem· January 2007

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