Publications by authors named "Julien Pytkowicz"

Claim this Profile
D
Design and synthesis of a clickable cell-permeable pseudopeptide Pin1 inhibitor with antiproliferative effects on human multiple myeloma cell line.
Lorenzo Meneghelli, Stephanie Davidson, Anthony Gineste, Lamia El Guermah, Sabrina Kellouche-Gaillard, Julien Pytkowicz

Chem Commun (Camb)· April 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis and biological evaluation of selective Pepstatin based trifluoromethylated inhibitors of Cathepsin D.
Francesco Terzani, Sherazade Belhattab, Aurore Le Guern, Karine Guitot, Olivier Monasson, Julien Pytkowicz

Eur J Med Chem· March 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
(
(R)-α-Trifluoromethylalanine as a F NMR Probe for the Monitoring of Protease Digestion of Peptides.
Emmanuelle Devillers, Evelyne Chelain, Claudio Dalvit, Thierry Brigaud, Julien Pytkowicz

Chembiochem· January 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Enantiopure α-Trifluoromethylated Aziridine-2-carboxylic Acid (α-TfmAzy): Synthesis and Peptide Coupling.
Oussema Ouerfelli, Julien Simon, Evelyne Chelain, Julien Pytkowicz, Rafâa Besbes

Org Lett· April 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Trifluoromethylated Proline Surrogates as Part of "Pro-Pro" Turn-Inducing Templates.
Charlène Gadais, Kevin Van Holsbeeck, Samuel L C Moors, Dieter Buyst, Krisztina Fehér, Julien Pytkowicz

Chembiochem· October 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Probing the Outstanding Local Hydrophobicity Increases in Peptide Sequences Induced by Incorporation of Trifluoromethylated Amino Acids.
Charlène Gadais, Emmanuelle Devillers, Vincent Gasparik, Evelyne Chelain, Julien Pytkowicz

Chembiochem· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Homochiral versus Heterochiral Trifluoromethylated Pseudoproline Containing Dipeptides: A Powerful Tool to Switch the Prolyl-Amide Bond Conformation.
Grégory Chaume, Julien Simon, Nathalie Lensen, Julien Pytkowicz, Thierry Brigaud

J Org Chem· December 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Incorporation of Trifluoromethylated Proline and Surrogates into Peptides: Application to the Synthesis of Fluorinated Analogues of the Neuroprotective Glycine-Proline-Glutamate (GPE) Tripeptide.
Julien Simon, Julien Pytkowicz, Nathalie Lensen, Grégory Chaume, Thierry Brigaud

J Org Chem· July 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis of protected enantiopure (R) and (S)-α-trifluoromethylalanine containing dipeptide building blocks ready to use for solid phase peptide synthesis.
Emmanuelle Devillers, Julien Pytkowicz, Evelyne Chelain, Thierry Brigaud

Amino Acids· June 2016

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synthesis of enantiopure trans-2,5-disubstituted trifluoromethylpyrrolidines and (2S,5R)-5-trifluoromethylproline.
Hodney Lubin, Julien Pytkowicz, Grégory Chaume, Gwenaëlle Sizun-Thomé, Thierry Brigaud

J Org Chem· March 2015

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Crystallization-induced dynamic resolution of Fox chiral auxiliary and application to the diastereoselective electrophilic fluorination of amide enolates.
Hodney Lubin, Christophe Dupuis, Julien Pytkowicz, Thierry Brigaud

J Org Chem· April 2013

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Straightforward synthesis of enantiopure (R)- and (S)-trifluoroalaninol.
Julien Pytkowicz, Olivier Stéphany, Sinisa Marinkovic, Sébastien Inagaki, Thierry Brigaud

Org Biomol Chem· October 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Highly diastereoselective alpha-hydroxylation of Fox chiral auxiliary-based amide enolates with molecular oxygen.
Hodney Lubin, Arnaud Tessier, Grégory Chaume, Julien Pytkowicz, Thierry Brigaud

Org Lett· April 2010

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Fluorine... and pi...alkali metal interactions control in the stereoselective amide enolate alkylation with fluorinated oxazolidines (Fox) as a chiral auxiliary: an experimental and theoretical study.
Gjergji Sini, Arnaud Tessier, Julien Pytkowicz, Thierry Brigaud

Chemistry· June 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
Highly diastereoselective synthetic route to enantiopure beta(2)-amino acids and gamma-amino alcohols using a fluorinated oxazolidine (Fox) as chiral auxiliary.
Arnaud Tessier, Nour Lahmar, Julien Pytkowicz, Thierry Brigaud

J Org Chem· May 2008

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Chiral 4-phenyl-2-trifluoromethyloxazolidine: a high-performance chiral auxiliary for the alkylation of amides.
Arnaud Tessier, Julien Pytkowicz, Thierry Brigaud

Angew Chem Int Ed Engl· May 2006

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Asymmetric, catalytic synthesis of alpha-chiral amines using a novel bis(phosphine) monoxide chiral ligand.
Alessandro A Boezio, Julien Pytkowicz, Alexandre Côté, André B Charette

J Am Chem Soc· November 2003

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis