Publications by authors named "Julius L Apuy"

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Formation of A Novel Purine Metabolite through CYP3A4 Bioactivation and Glutathione Conjugation.
Julius L Apuy, Cathie Xiang, Sarah Franc, Sayee G Hegde, Robert Hubbard

Drug Metab Lett· October 2017

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Application of 1D and 2D 1H-NMR in the structural elucidation of a N-glucuronidated metabolite and oxidized metabolites generated in microsomal incubation.
Julius L Apuy, April Bai, David Paisner, Sayee G Hegde, Mehran F Moghaddam

Drug Metab Lett· October 2013

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CEP-32496: a novel orally active BRAF(V600E) inhibitor with selective cellular and in vivo antitumor activity.
Joyce James, Bruce Ruggeri, Robert C Armstrong, Martin W Rowbottom, Susan Jones-Bolin, Julius L Apuy

Mol Cancer Ther· April 2012

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Discovery of highly potent and selective pan-Aurora kinase inhibitors with enhanced in vivo antitumor therapeutic index.
Gang Liu, Sunny Abraham, Lan Tran, Troy D Vickers, Shimin Xu, Julius L Apuy

J Med Chem· April 2012

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Identification of 1-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)-3-(5-(1,1,1-trifluoro-2-methylpropan-2-yl)isoxazol-3-yl)urea hydrochloride (CEP-32496), a highly potent and orally efficacious inhibitor of V-RAF murine sarcoma viral oncogene homologue B1 (BRAF) V600E.
Martin W Rowbottom, Raffaella Faraoni, Qi Chao, Brian T Campbell, Andiliy G Lai, Julius L Apuy

J Med Chem· February 2012

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Ratiometric pulsed alkylation mass spectrometry as a probe of thiolate reactivity in different metalloderivatives of Staphylococcus aureus pI258 CadC.
Julius L Apuy, Laura S Busenlehner, David H Russell, David P Giedroc

Biochemistry· April 2004

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Characterization of a metalloregulatory bismuth(III) site in Staphylococcus aureus pI258 CadC repressor.
Laura S Busenlehner, Julius L Apuy, David P Giedroc

J Biol Inorg Chem· April 2002

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