Publications by authors named "June Goto"

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The choroid plexus maintains adult brain ventricles and subventricular zone neuroblast pool, which facilitates poststroke neurogenesis.
Aleksandr Taranov, Alicia Bedolla, Eri Iwasawa, Farrah N Brown, Sarah Baumgartner, June Goto

Proc Natl Acad Sci U S A· July 2024

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The choroid plexus maintains ventricle volume and adult subventricular zone neuroblast pool, which facilitates post-stroke neurogenesis.
Aleksandr Taranov, Alicia Bedolla, Eri Iwasawa, Farrah N Brown, Sarah Baumgartner, June Goto

bioRxiv· January 2024

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Early postnatal microglial ablation in the Ccdc39 mouse model reveals adverse effects on brain development and in neonatal hydrocephalus.
Farrah N Brown, Eri Iwasawa, Crystal Shula, Elizabeth M Fugate, Diana M Lindquist, June Goto

Fluids Barriers CNS· June 2023

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Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus.
Phan Q Duy, Stefan C Weise, Claudia Marini, Xiao-Jun Li, Dan Liang, June Goto

Nat Neurosci· April 2022

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The Anti-Inflammatory Agent Bindarit Attenuates the Impairment of Neural Development through Suppression of Microglial Activation in a Neonatal Hydrocephalus Mouse Model.
Eri Iwasawa, Farrah N Brown, Crystal Shula, Fatima Kahn, Sang Hoon Lee, June Goto

J Neurosci· March 2022

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Diphtheria toxin induced but not CSF1R inhibitor mediated microglia ablation model leads to the loss of CSF/ventricular spaces in vivo that is independent of cytokine upregulation.
Alicia Bedolla, Aleksandr Taranov, Fucheng Luo, Jiapeng Wang, Flavia Turcato, June Goto

J Neuroinflammation· January 2022

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Hydrocephalus in mouse B3glct mutants is likely caused by defects in multiple B3GLCT substrates in ependymal cells and subcommissural organ.
Sanjiv Neupane, June Goto, Steven J Berardinelli, Atsuko Ito, Robert S Haltiwanger

Glycobiology· September 2021

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Exome sequencing implicates genetic disruption of prenatal neuro-gliogenesis in sporadic congenital hydrocephalus.
Sheng Chih Jin, Weilai Dong, Adam J Kundishora, Shreyas Panchagnula, Andres Moreno-De-Luca, June Goto

Nat Med· November 2020

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Neonatal hydrocephalus leads to white matter neuroinflammation and injury in the corpus callosum of Ccdc39 hydrocephalic mice.
Danielle S Goulding, R Caleb Vogel, Chirayu D Pandya, Crystal Shula, John C Gensel, June Goto

J Neurosurg Pediatr· May 2020

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Impaired neural differentiation and glymphatic CSF flow in the rat model of neonatal hydrocephalus: genetic interaction with .
A Scott Emmert, Eri Iwasawa, Crystal Shula, Preston Schultz, Diana Lindquist, June Goto

Dis Model Mech· November 2019

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Characterization of a novel rat model of X-linked hydrocephalus by CRISPR-mediated mutation in L1cam.
A Scott Emmert, Shawn M Vuong, Crystal Shula, Diana Lindquist, Weihong Yuan, June Goto

J Neurosurg· February 2019

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A mutation in causes neonatal hydrocephalus with abnormal motile cilia development in mice.
Zakia Abdelhamed, Shawn M Vuong, Lauren Hill, Crystal Shula, Andrew Timms, June Goto

Development· January 2018

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Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model.
Shilpa Prabhakar, Xuan Zhang, June Goto, Sangyeul Han, Charles Lai

Neurobiol Dis· October 2015

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Brain-expressed X-linked 2 Is Pivotal for Hyperactive Mechanistic Target of Rapamycin (mTOR)-mediated Tumorigenesis.
Zhongdong Hu, Ying Wang, Fuqiang Huang, Rongrong Chen, Chunjia Li, June Goto

J Biol Chem· October 2015

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Neuronal Tsc1/2 complex controls autophagy through AMPK-dependent regulation of ULK1.
Alessia Di Nardo, Mary H Wertz, Erica Kwiatkowski, Peter T Tsai, Jarrett D Leech, June Goto

Hum Mol Genet· July 2014

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Stochastic model of Tsc1 lesions in mouse brain.
Shilpa Prabhakar, June Goto, Xuan Zhang, Miguel Sena-Esteves, Roderick Bronson

PLoS One· December 2013

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Prenatal rapamycin results in early and late behavioral abnormalities in wildtype C57BL/6 mice.
Peter T Tsai, Emily Greene-Colozzi, June Goto, Stefanie Anderl, David J Kwiatkowski

Behav Genet· January 2013

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Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex.
Stefanie Anderl, Megan Freeland, David J Kwiatkowski, June Goto

Hum Mol Genet· December 2011

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Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
June Goto, Delia M Talos, Peter Klein, Wei Qin, Yvonne I Chekaluk

Proc Natl Acad Sci U S A· November 2011

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Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin.
Amy J Malhowski, Haider Hira, Sarah Bashiruddin, Rod Warburton, June Goto

Hum Mol Genet· April 2011

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Mammalian target of rapamycin up-regulation of pyruvate kinase isoenzyme type M2 is critical for aerobic glycolysis and tumor growth.
Qian Sun, Xinxin Chen, Jianhui Ma, Haiyong Peng, Fang Wang, June Goto

Proc Natl Acad Sci U S A· March 2011

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A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles.
Kristen Pollizzi, Izabela Malinowska-Kolodziej, Cheryl Doughty, Charles Betz, Jian Ma, June Goto

Hum Mol Genet· July 2009

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Loss of Fyn tyrosine kinase on the C57BL/6 genetic background causes hydrocephalus with defects in oligodendrocyte development.
June Goto, Tohru Tezuka, Takanobu Nakazawa, Hiroshi Sagara, Tadashi Yamamoto

Mol Cell Neurosci· June 2008

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NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity.
Takanobu Nakazawa, Shoji Komai, Ayako M Watabe, Yuji Kiyama, Masahiro Fukaya, June Goto

EMBO J· June 2006

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Altered gene expression in the adult brain of fyn-deficient mice.
June Goto, Tohru Tezuka, Takanobu Nakazawa, Nobuo Tsukamoto, Takahisa Nakamura

Cell Mol Neurobiol· February 2004

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