Publications by authors named "Junko Tamiya"

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Covalent inhibitors of the PI3Kα RAS binding domain impair tumor growth driven by RAS and HER2.
Joseph E Klebba, Nilotpal Roy, Steffen M Bernard, Stephanie Grabow, Melissa A Hoffman, Junko Tamiya

Science· November 2025

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Covalent inhibitors of the RAS binding domain of PI3Kα impair tumor growth driven by RAS and HER2.
Joseph E Klebba, Nilotpal Roy, Steffen M Bernard, Stephanie Grabow, Melissa A Hoffman, Junko Tamiya

bioRxiv· December 2024

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Imidazoline 1 receptor activation preserves respiratory drive in spontaneously breathing newborn rats during dexmedetomidine administration.
Nana Sato, Chikako Saiki, Junko Tamiya, Toshio Imai, Katsuhisa Sunada

Paediatr Anaesth· May 2017

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Effects of dexmedetomidine on cardiorespiratory regulation in spontaneously breathing newborn rats.
Junko Tamiya, Ryoji Ide, Masayuki Takahashi, Chikako Saiki

Paediatr Anaesth· December 2014

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Characterization of thien-2-yl 1S,2R-milnacipran analogues as potent norepinephrine/serotonin transporter inhibitors for the treatment of neuropathic pain.
Brian Dyck, Junko Tamiya, Florence Jovic, Rebecca R Pick, Margaret J Bradbury

J Med Chem· November 2008

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Studies on the structure-activity relationship of bicifadine analogs as monoamine transporter inhibitors.
Mingzhu Zhang, Florence Jovic, Troy Vickers, Brian Dyck, Junko Tamiya

Bioorg Med Chem Lett· July 2008

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Identification of 1S,2R-milnacipran analogs as potent norepinephrine and serotonin transporter inhibitors.
Junko Tamiya, Brian Dyck, Mingzhu Zhang, Kasey Phan, Beth A Fleck

Bioorg Med Chem Lett· June 2008

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Studies on a series of milnacipran analogs containing a heteroaromatic group as potent norepinephrine and serotonin transporter inhibitors.
Troy Vickers, Brian Dyck, Junko Tamiya, Mingzhu Zhang, Florence Jovic

Bioorg Med Chem Lett· June 2008

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Studies on the SAR and pharmacophore of milnacipran derivatives as monoamine transporter inhibitors.
Chen Chen, Brian Dyck, Beth A Fleck, Alan C Foster, Jonathan Grey, Junko Tamiya

Bioorg Med Chem Lett· February 2008

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Thienopyrimidinone bis-aminopyrrolidine ureas as potent melanin-concentrating hormone receptor-1 (MCH-R1) antagonists.
Mingzhu Zhang, Junko Tamiya, Linh Nguyen, Martin W Rowbottom, Brian Dyck

Bioorg Med Chem Lett· May 2007

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Synthesis and structure-activity relationships of spirohydantoin-derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).
Martin W Rowbottom, Troy D Vickers, Junko Tamiya, Mingzhu Zhang, Brian Dyck

Bioorg Med Chem Lett· April 2007

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Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1.
Martin W Rowbottom, Troy D Vickers, Brian Dyck, Jonathan Grey, Junko Tamiya

Bioorg Med Chem Lett· September 2006

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Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists.
Brian Dyck, Liren Zhao, Junko Tamiya, Joseph Pontillo, Sarah Hudson

Bioorg Med Chem Lett· August 2006

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A thienopyridazinone-based melanin-concentrating hormone receptor 1 antagonist with potent in vivo anorectic properties.
Brian Dyck, Stacy Markison, Liren Zhao, Junko Tamiya, Jonathan Grey

J Med Chem· June 2006

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Synthesis and structure-activity relationships of biarylcarboxamide bis-aminopyrrolidine urea derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1).
Martin W Rowbottom, Troy D Vickers, Brian Dyck, Junko Tamiya, Mingzhu Zhang

Bioorg Med Chem Lett· July 2005

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Bis(aminopyrrolidine)-derived ureas (APUs) as potent MCH1 receptor antagonists.
Jonathan Grey, Brian Dyck, Martin W Rowbottom, Junko Tamiya, Troy D Vickers

Bioorg Med Chem Lett· February 2005

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