Publications by authors named "Justin Anglin"

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Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.
Ram K Modukuri, Zhifeng Yu, Zhi Tan, Hai Minh Ta, Melek Nihan Ucisik, Justin L Anglin

Proc Natl Acad Sci U S A· May 2022

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Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Producing OXA-48.
Doris Mia Taylor, Justin Anglin, Liya Hu, Lingfei Wang, Banumathi Sankaran

ACS Infect Dis· December 2021

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Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
Zhifeng Yu, Angela F Ku, Justin L Anglin, Rajesh Sharma, Melek Nihan Ucisik

Proc Natl Acad Sci U S A· March 2021

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Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries.
Doris Mia Taylor, Justin Anglin, Suhyeorn Park, Melek N Ucisik, John C Faver

ACS Infect Dis· May 2020

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A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer.
Natasha C Lucki, Genaro R Villa, Naja Vergani, Michael J Bollong, Brittney A Beyer, Justin L Anglin

Proc Natl Acad Sci U S A· March 2019

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Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors.
Melissa C Holt, Zahra Assar, Reza Beheshti Zavareh, Lin Lin, Justin Anglin

Biochemistry· November 2018

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Discovery and optimization of aspartate aminotransferase 1 inhibitors to target redox balance in pancreatic ductal adenocarcinoma.
Justin Anglin, Reza Beheshti Zavareh, Philipp N Sander, Daniel Haldar, Edouard Mullarky

Bioorg Med Chem Lett· September 2018

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Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics.
Kenneth M Lum, Yoshiaki Sato, Brittney A Beyer, Warren C Plaisted, Justin L Anglin

ACS Chem Biol· October 2017

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Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.
Edouard Mullarky, Natasha C Lucki, Reza Beheshti Zavareh, Justin L Anglin, Ana P Gomes

Proc Natl Acad Sci U S A· February 2016

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A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L.
Justin L Anglin, Yongcheng Song

J Med Chem· November 2013

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Crystallographic Investigation and Selective Inhibition of Mutant Isocitrate Dehydrogenase.
Baisong Zheng, Yuan Yao, Zhen Liu, Lisheng Deng, Justin L Anglin

ACS Med Chem Lett· June 2013

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Synthesis and structure-activity relationship investigation of adenosine-containing inhibitors of histone methyltransferase DOT1L.
Justin L Anglin, Lisheng Deng, Yuan Yao, Guobin Cai, Zhen Liu

J Med Chem· September 2012

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Selective inhibitors of histone methyltransferase DOT1L: design, synthesis, and crystallographic studies.
Yuan Yao, Pinhong Chen, Jiasheng Diao, Gang Cheng, Lisheng Deng, Justin L Anglin

J Am Chem Soc· October 2011

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Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii.
Sethu C Nair, Carrie F Brooks, Christopher D Goodman, Angelika Sturm, Geoffrey I McFadden, Justin L Anglin

J Exp Med· July 2011

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