Publications by authors named "Kenneth M Lum"

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Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron.
Laura J Keller, Taylor H Nguyen, Lawrence J Liu, Brianna M Hurysz, Markus Lakemeyer, Kenneth M Lum

Nat Chem Biol· December 2023

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Chemoproteomics-Enabled Identification of 4-Oxo-β-Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9.
Luís A R Carvalho, Breyan Ross, Lorenz Fehr, Oguz Bolgi, Svenja Wöhrle, Kenneth M Lum

Angew Chem Int Ed Engl· November 2022

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Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host.
Ouma Onguka, Brett M Babin, Markus Lakemeyer, Ian T Foe, Neri Amara, Kenneth M Lum

Cell Chem Biol· October 2021

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ABHD17 regulation of plasma membrane palmitoylation and N-Ras-dependent cancer growth.
Jarrett R Remsberg, Radu M Suciu, Noemi A Zambetti, Thomas W Hanigan, Ari J Firestone, Kenneth M Lum

Nat Chem Biol· August 2021

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An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells.
Ekaterina V Vinogradova, Xiaoyu Zhang, David Remillard, Daniel C Lazar, Radu M Suciu, Kenneth M Lum

Cell· August 2020

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Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator.
Dogukan Mizrak, N Sumru Bayin, Jinzhou Yuan, Zhouzerui Liu, Radu M Suciu, Kenneth M Lum

Cell Rep· June 2020

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AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice.
Meric Erikci Ertunc, Bernard P Kok, William H Parsons, Justin G Wang, Dan Tan, Kenneth M Lum

J Biol Chem· May 2020

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3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling.
Luís A R Carvalho, Vanessa T Almeida, José A Brito, Kenneth M Lum, Tânia F Oliveira

ACS Chem Biol· April 2020

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Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan.
Alice L Chen, Kenneth M Lum, Pablo Lara-Gonzalez, Daisuke Ogasawara, Armand B Cognetta

Nat Chem Biol· May 2019

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Multicomponent mapping of boron chemotypes furnishes selective enzyme inhibitors.
Joanne Tan, Armand B Cognetta Iii, Diego B Diaz, Kenneth M Lum, Shinya Adachi

Nat Commun· November 2017

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Mapping Protein Targets of Bioactive Small Molecules Using Lipid-Based Chemical Proteomics.
Kenneth M Lum, Yoshiaki Sato, Brittney A Beyer, Warren C Plaisted, Justin L Anglin

ACS Chem Biol· October 2017

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Metabolically Labile Fumarate Esters Impart Kinetic Selectivity to Irreversible Inhibitors.
Balyn W Zaro, Landon R Whitby, Kenneth M Lum, Benjamin F Cravatt

J Am Chem Soc· December 2016

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An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers.
Genaro R Villa, Jonathan J Hulce, Ciro Zanca, Junfeng Bi, Shiro Ikegami, Kenneth M Lum

Cancer Cell· November 2016

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Chemical Proteomic Profiling of Human Methyltransferases.
Benjamin D Horning, Radu M Suciu, Darian A Ghadiri, Olesya A Ulanovskaya, Megan L Matthews, Kenneth M Lum

J Am Chem Soc· October 2016

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Proteome-wide covalent ligand discovery in native biological systems.
Keriann M Backus, Bruno E Correia, Kenneth M Lum, Stefano Forli, Benjamin D Horning

Nature· June 2016

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A Global Map of Lipid-Binding Proteins and Their Ligandability in Cells.
Micah J Niphakis, Kenneth M Lum, Armand B Cognetta, Bruno E Correia, Taka-Aki Ichu

Cell· June 2015

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Stabilized Wittig olefination for bioconjugation.
Kenneth M Lum, Vanessa J Xavier, Michelle J-H Ong, Charles W Johannes, Kok-Ping Chan

Chem Commun (Camb)· December 2013

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Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates.
Jae Won Chang, Micah J Niphakis, Kenneth M Lum, Armand B Cognetta, Chu Wang

Chem Biol· May 2012

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