Publications by authors named "Justin Hay"

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Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics.
Justin L Hay, Amandine Manon, Hunter Stephens, S Y Amy Cheung, Bart de Keizer

Br J Clin Pharmacol· December 2025

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Pediatric oncology drug development and dosage optimization.
S Y Amy Cheung, Justin L Hay, Yu-Wei Lin, Rik de Greef, Julie Bullock

Front Oncol· January 2024

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Application of exposure bracketing to streamline the development of contraceptive products.
Joshua Brown, Tamra Goodrow, Dan Hartman, Justin L Hay, Kevin Hershberger

Contracept X· January 2022

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Harnessing formulation and clinical pharmacology knowledge for efficient pediatric drug development: Overview and discussions from M-CERSI pediatric formulation workshop 2019.
Yuet Mei Khong, Jing Liu, Jack Cook, Vivek Purohit, Karen Thompson, Justin L Hay

Eur J Pharm Biopharm· July 2021

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Stability analysis of clustering of Norris' visual analogue scale: Applying the consensus clustering approach.
Zheng Guan, X Gregory Chen, Justin Hay, Joop van Gerven, Jacobus Burggraaf

Medicine (Baltimore)· April 2021

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A review of clinical pharmacology deficiencies of European centralised drug marketing authorisation applications.
Justin L Hay, Jane O'Sullivan, Essam Kerwash, Alexandra-Roxana Ilie, Susan M Cole

Regul Toxicol Pharmacol· December 2020

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Streamlined approval of biosimilars: moving on from the confirmatory efficacy trial.
Marie-Christine Bielsky, Anne Cook, Andrea Wallington, Andrew Exley, Shahin Kauser, Justin L Hay

Drug Discov Today· September 2020

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Lack of Detection of the Analgesic Properties of PF-05089771, a Selective Na 1.7 Inhibitor, Using a Battery of Pain Models in Healthy Subjects.
Pieter Siebenga, Guido van Amerongen, Justin L Hay, Aoibhinn McDonnell, Donal Gorman

Clin Transl Sci· March 2020

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Analgesic potential of PF-06372865, an α2/α3/α5 subtype-selective GABA partial agonist, in humans.
Guido van Amerongen, Pieter S Siebenga, Rachel Gurrell, Pinky Dua, Mark Whitlock, Justin L Hay

Br J Anaesth· August 2019

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Reproducibility of a battery of human evoked pain models to detect pharmacological effects of analgesic drugs.
Pieter S Siebenga, Guido van Amerongen, Pieter Okkerse, William S Denney, Pinky Dua, Justin L Hay

Eur J Pain· July 2019

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The EMA Review of Mylotarg (Gemtuzumab Ozogamicin) for the Treatment of Acute Myeloid Leukemia.
Sahra Ali, Helen-Marie Dunmore, Dominik Karres, Justin L Hay, Tomas Salmonsson

Oncologist· May 2019

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Demonstration of an anti-hyperalgesic effect of a novel pan-Trk inhibitor PF-06273340 in a battery of human evoked pain models.
Peter Loudon, Pieter Siebenga, Donal Gorman, Katrina Gore, Pinky Dua, Justin L Hay

Br J Clin Pharmacol· February 2018

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Commentary on the MID3 Good Practices Paper.
Efthymios Manolis, Jacob Brogren, Susan Cole, Justin L Hay, Anna Nordmark

CPT Pharmacometrics Syst Pharmacol· July 2017

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The use of a battery of pain models to detect analgesic properties of compounds: a two-part four-way crossover study.
Pieter Okkerse, Guido van Amerongen, Marieke L de Kam, Jasper Stevens, Richard P Butt, Justin L Hay

Br J Clin Pharmacol· May 2017

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Pharmacokinetics and pharmacodynamics of intrathecally administered Xen2174, a synthetic conopeptide with norepinephrine reuptake inhibitor and analgesic properties.
Pieter Okkerse, Justin L Hay, Elske Sitsen, Albert Dahan, Erica Klaassen

Br J Clin Pharmacol· April 2017

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Respiratory Effects of the Nociceptin/Orphanin FQ Peptide and Opioid Receptor Agonist, Cebranopadol, in Healthy Human Volunteers.
Albert Dahan, Merel Boom, Elise Sarton, Justin Hay, Geert Jan Groeneveld

Anesthesiology· April 2017

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Effects of a single, oral 60 mg caffeine dose on attention in healthy adult subjects.
Micha Mm Wilhelmus, Justin L Hay, Rob Gja Zuiker, Pieter Okkerse, Christelle Perdrieu

J Psychopharmacol· February 2017

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A literature review on the pharmacological sensitivity of human evoked hyperalgesia pain models.
Guido van Amerongen, Matthijs W de Boer, Geert Jan Groeneveld, Justin L Hay

Br J Clin Pharmacol· October 2016

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Model-based exposure-response analysis to quantify age related differences in the response to scopolamine in healthy subjects.
Ricardo Alvarez-Jimenez, Geert Jan Groeneveld, Joop M A van Gerven, Sebastiaan C Goulooze, Anne Catrien Baakman, Justin L Hay

Br J Clin Pharmacol· October 2016

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Responsiveness of electrical nociceptive detection thresholds to capsaicin (8 %)-induced changes in nociceptive processing.
Robert J Doll, Guido van Amerongen, Justin L Hay, Geert J Groeneveld, Peter H Veltink

Exp Brain Res· September 2016

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Pharmacokinetics and pharmacodynamics of multiple doses of BG00010, a neurotrophic factor with anti-hyperalgesic effects, in patients with sciatica.
Pieter Okkerse, Justin L Hay, Eve Versage, Yongqiang Tang, Gerald Galluppi

Br J Clin Pharmacol· July 2016

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Measuring blood-brain barrier penetration using the NeuroCart, a CNS test battery.
Geert Jan Groeneveld, Justin Luke Hay, Johannes Marinus Van Gerven

Drug Discov Today Technol· June 2016

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Determining Pain Detection and Tolerance Thresholds Using an Integrated, Multi-Modal Pain Task Battery.
Justin L Hay, Pieter Okkerse, Guido van Amerongen, Geert Jan Groeneveld

J Vis Exp· April 2016

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The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels.
Erik T Te Beek, Xia Chen, Gabriël E Jacobs, Kimberly J Nahon, Marieke L de Kam, Justin L Hay

Clin Pharmacol Drug Dev· March 2015

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Two studies on reversal of opioid-induced respiratory depression by BK-channel blocker GAL021 in human volunteers.
Margot Roozekrans, Rutger van der Schrier, Pieter Okkerse, Justin Hay, James F McLeod

Anesthesiology· September 2014

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