Publications by authors named "Kade D Roberts"

Claim this Profile
S
Structure-Activity Relationship of the Diaminobutyric Acid Residues in Polymyxins.
Wendong Ma, Xukai Jiang, Kaijie Mu, Sixin Tian, Heidi H Yu, Kade D Roberts

JACS Au· October 2025

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
E
Exploring Structure-Activity Relationships and Modes of Action of Laterocidine.
Varsha J Thombare, James D Swarbrick, Mohammad A K Azad, Yan Zhu, Jing Lu, Kade D Roberts

ACS Cent Sci· September 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
Advancing Nitrile-Aminothiol Strategy for Dual and Sequential Bioconjugation.
Varsha J Thombare, Yimin Wu, Kavya Pamulapati, Meiling Han, Julien Tailhades, Kade D Roberts

Chemistry· August 2024

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Interaction Relationship of Polymyxins with Lung Surfactant.
Xukai Jiang, Nitin A Patil, Yuwen Xu, Hasini Wickremasinghe, Qi Tony Zhou, Kade D Roberts

J Med Chem· December 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Synchrotron-based X-ray fluorescence microscopy reveals accumulation of polymyxins in single human alveolar epithelial cells.
Mohamad A K Azad, Shuo Zhang, Jiayao Li, Yeonuk Kim, Heidi H Yu, Kade D Roberts

Antimicrob Agents Chemother· May 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
C
Critical Role of Position 10 Residue in the Polymyxin Antimicrobial Activity.
Nitin A Patil, Wendong Ma, Xukai Jiang, Xiaoji He, Heidi H Yu, Kade D Roberts

J Med Chem· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
Transcriptomic Responses to Polymyxin B and Analogues in Human Kidney Tubular Cells.
Mengyao Li, Mohammad A K Azad, Philip E Thompson, Kade D Roberts, Tony Velkov

Antibiotics (Basel)· February 2023

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Intelligent Strategy with All-Atom Molecular Dynamics Simulations for the Design of Lipopeptides against Multidrug-Resistant .
Xukai Jiang, Meiling Han, Kevin Tran, Nitin A Patil, Wendong Ma, Kade D Roberts

J Med Chem· July 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A synthetic lipopeptide targeting top-priority multidrug-resistant Gram-negative pathogens.
Kade D Roberts, Yan Zhu, Mohammad A K Azad, Mei-Ling Han, Jiping Wang

Nat Commun· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
An Efficient Approach for the Design and Synthesis of Antimicrobial Peptide-Peptide Nucleic Acid Conjugates.
Nitin A Patil, Varsha J Thombare, Rong Li, Xiaoji He, Jing Lu, Kade D Roberts

Front Chem· March 2022

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
A
A novel chemical biology and computational approach to expedite the discovery of new-generation polymyxins against life-threatening .
Xukai Jiang, Nitin A Patil, Mohammad A K Azad, Hasini Wickremasinghe, Heidi Yu, Kade D Roberts

Chem Sci· September 2021

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Molecular dynamics simulations informed by membrane lipidomics reveal the structure-interaction relationship of polymyxins with the lipid A-based outer membrane of Acinetobacter baumannii.
Xukai Jiang, Kai Yang, Bing Yuan, Meiling Han, Yan Zhu, Kade D Roberts

J Antimicrob Chemother· December 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Simulations of octapeptin-outer membrane interactions reveal conformational flexibility is linked to antimicrobial potency.
Xukai Jiang, Kai Yang, Bing Yuan, Bin Gong, Lin Wan, Kade D Roberts

J Biol Chem· November 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure-Interaction Relationship of Polymyxins with the Membrane of Human Kidney Proximal Tubular Cells.
Xukai Jiang, Shuo Zhang, Mohammad A K Azad, Kade D Roberts, Lin Wan

ACS Infect Dis· August 2020

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
H
History, Chemistry and Antibacterial Spectrum.
Tony Velkov, Philip E Thompson, Mohammad A K Azad, Kade D Roberts, Phillip J Bergen

Adv Exp Med Biol· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Discovery of Novel Polymyxin-Like Antibiotics.
Tony Velkov, Kade D Roberts

Adv Exp Med Biol· September 2019

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Sputum Active Polymyxin Lipopeptides: Activity against Cystic Fibrosis Pseudomonas aeruginosa Isolates and Their Interactions with Sputum Biomolecules.
Elena K Schneider-Futschik, Olivia K A Paulin, Daniel Hoyer, Kade D Roberts, James Ziogas

ACS Infect Dis· May 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
S
Structure, Function, and Biosynthetic Origin of Octapeptin Antibiotics Active against Extensively Drug-Resistant Gram-Negative Bacteria.
Tony Velkov, Alejandra Gallardo-Godoy, James D Swarbrick, Mark A T Blaskovich, Alysha G Elliott, Kade D Roberts

Cell Chem Biol· April 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
M
Methionine Ameliorates Polymyxin-Induced Nephrotoxicity by Attenuating Cellular Oxidative Stress.
Mohammad A K Azad, Sivashangarie Sivanesan, Jiping Wang, Ke Chen, Roger L Nation, Kade D Roberts

Antimicrob Agents Chemother· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
P
Polymyxin-Induced Lipid A Deacylation in Pseudomonas aeruginosa Perturbs Polymyxin Penetration and Confers High-Level Resistance.
Mei-Ling Han, Tony Velkov, Yan Zhu, Kade D Roberts, Anton P Le Brun

ACS Chem Biol· January 2018

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
D
Design and Evaluation of Novel Polymyxin Fluorescent Probes.
Bo Yun, Kade D Roberts, Philip E Thompson, Roger L Nation, Tony Velkov

Sensors (Basel)· November 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
I
Investigating the Interaction of Octapeptin A3 with Model Bacterial Membranes.
Mei-Ling Han, Hsin-Hui Shen, Karl A Hansford, Elena K Schneider, Sivashangarie Sivanesan, Kade D Roberts

ACS Infect Dis· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
T
The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity.
Simon J Mountford, Biswaranjan Mohanty, Kade D Roberts, Heidi H Yu, Martin J Scanlon

Org Biomol Chem· August 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
R
Rediscovering the octapeptins.
Tony Velkov, Kade D Roberts, Jian Li

Nat Prod Rep· March 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis
F
Functional Characterization of the Unique Terminal Thioesterase Domain from Polymyxin Synthetase.
Charles A Galea, Kade D Roberts, Yan Zhu, Philip E Thompson, Jian Li

Biochemistry· January 2017

Social Media Activity not collected for this article yet.

Sign Up to Request Social Media Analysis