Publications by authors named "Kai-Uwe Lewandrowski"

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Surgeon Skill Level, Experience, and Impact on Patient Outcomes: Rethinking Research Paradigms in Spine Surgery.
Kai-Uwe Lewandrowski, Morgan P Lorio, Oscar L Alves, Rossano Kepler Alvim Fiorelli, Sergio Luis Schmidt

Int J Spine Surg· December 2025

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Prehabilitation Reimagined as Policy: A Multidimensional Framework to Reduce Pain, Opioid Use, and Surgical Risk.
Kai-Uwe Lewandrowski, Morgan P Lorio, Igor Elman, Kenneth Blum, Albert Pinhasov

Int J Spine Surg· December 2025

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Billions Spent, Few Saved: Rethinking National Institutes of Health HEAL Initiative in Light of Dopaminergic Alternatives to the Opioid Trap.
Kai-Uwe Lewandrowski, Kenneth Blum, Morgan P Lorio, Sergio Luis Schmidt, Rossano Kepler Alvim Fiorelli

Int J Spine Surg· December 2025

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ISASS Recommendations and Coverage Criteria for Restorative Neurostimulation for Multifidus Dysfunction, Lumbar Region: Coverage Indications, Limitations, and/or Medical Necessity-An ISASS 2025 Guideline Update.
Morgan P Lorio, Kai-Uwe Lewandrowski, William Lavelle, David A Essig, James Yue

Int J Spine Surg· December 2025

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Regenerative and Wellness Medicine: A Boon or Barrier to Surgical Innovation in Degenerative Spine Care?
Álvaro Dowling, Kai-Uwe Lewandrowski, Morgan P Lorio, Óscar L Alves, Rossano Kepler Alvim Fiorelli

Int J Spine Surg· December 2025

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Exercise-driven modulation of glutamatergic signaling: mechanisms and clinical implications.
Candice Yu, John R Tyler, Igor Elman, Kenneth Blum, Kai Uwe Lewandrowski

Neuroscience· November 2025

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Computational GWAS Meta Meta Analysis Revealing Cross Talk Between Cannabis CNR1 and DRD2 Receptors Optimizing Long-Term Outcomes for Cannabis Use Disorder (CUD) By Enhancing Dopamine Homeostasis Promoting High-Quality Cannabis Medicinals.
Kenneth Blum, Alireza Sharafshah, Jag Khalsa, Kai-Uwe Lewandrowski, Panayotis K Thanos, Alexander P L Lewandrowski

Res Sq· November 2025

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Correction: Targeting pro-dopaminergic agonism to attenuate depression in patients displaying genetic/epigenetic predisposition to hypodopaminergia.
Kai-Uwe Lewandrowski, Kenneth Blum, Alexander P L Lewandrowski, Panayotis K Thanos, Albert Pinhasov

Front Public Health· November 2025

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Current Practice and Evidence for Endoscopic Spine Surgery.
Kai-Uwe Lewandrowski, Jason Pittman, Sam Joseph, Choll Kim, Christopher Yeung

J Am Acad Orthop Surg· November 2025

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Bringing Back Theorizing Medical Hypotheses to Spine Surgery Research in an Age of Overreliance on Randomized Controlled Trials.
Kai-Uwe Lewandrowski, Morgan P Lorio, Óscar L Alves, Rossano Kepler Alvim Fiorelli, Sergio Luis Schmidt

Int J Spine Surg· October 2025

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Long-COVID-19 and Cognition: Persistent attention deficits after hospital discharge.
Aureo do Carmo Filho, Max Kopti Fakoury, Guilherme Janeiro Schmidt, Ana Lucia Taboada Gjorup, André Casarsa Marques, Kai-Uwe Lewandrowski

J Psychiatr Res· September 2025

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Opioid-Induced Hyperalgesia and Inflammaging in the Management of Spine Pain: The Case for Genetically Directed Dopamine Homeostasis.
Kai-Uwe Lewandrowski, Rossano Kepler Alvim Fiorelli, Sergio Schmidt, Alireza Sharafshah, David Baron

Int J Spine Surg· September 2025

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Retiring CPT 62380: Why Endoscopic Lumbar Decompression Should Be Defined by Surgical Work, Not Optics.
Morgan P Lorio, Kai-Uwe Lewandrowski,

Int J Spine Surg· September 2025

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Correction: Cocaine self-administration attenuates brain glucose metabolism and functional connectivity in rats.
Christopher Rowan, Colin Hanna, Munawwar Sajjad, Rutao Yao, Alireza Sharafshah, Kai-Uwe Lewandrowski

PLoS One· September 2025

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PGx-Based in silico Analyses Identifies the Interactive Role of Genes, Glucose Metabolism and Dopaminergic Dysfunctional Pathways with Chronic Cocaine use and Misuse.
Alireza Sharafshah, Panayotis K Thanos, Albert Pinhasov, Abdalla Bowirrat, Colin Hanna, Kai-Uwe Lewandrowski, Alexander Pl Lewandrowski

Curr Neuropharmacol· September 2025

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Targeting pro-dopaminergic agonism to attenuate depression in patients displaying genetic/epigenetic predisposition to hypodopaminergia.
Kai-Uwe Lewandrowski, Kenneth Blum, Alexander P L Lewandrowski, Panayotis K Thanos, Albert Pinhasov

Front Public Health· September 2025

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Precision Genomics: A Reality Having Universal Impact in a New Era of Psychiatry - Lessons Learned, Past and Present.
Kenneth Blum, Alireza Sharafshah, Jag Khalsa, Kai Uwe-Lewandrowski, Kavya Mohankumar, Alexander P L Lewandrowski

J Addict Psychiatry· August 2025

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Ketamine's Role in Neuroinflammation and Neuroprotection Across Neurological and Psychiatric Disorders: A Narrative Review.
Gustavo N Silva, Virna G A Brandão, Kenneth Blum, Kai-Uwe Lewandrowski, Rossano K A Fiorelli

Pharmaceuticals (Basel)· August 2025

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A GWAS Meta-meta-analysis and In-depth Silico Pharmacogenomic Investigations in Identification of APOE and Other Genes Associated with Pain, Anti-inflammatory, and Immunomodulating Agents in Opioid Use Disorder (OUD) Derived from 14.91 M Subjects.
Alireza Sharafshah, Majid Motovali-Bashi, Kenneth Blum, Kai-Uwe Lewandrowski, Mark S Gold

Cell Mol Neurobiol· July 2025

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Demographic Shifts and Disease Burden in Brazil: Analyzing Future Healthcare Trends and Expenditure Needs.
Rossano Kepler Alvim Fiorelli, Kai-Uwe Lewandrowski, Alexandre Siciliano, Sergio Luis Schmidt, Paulo Sérgio Teixeira de Carvalho

Curr Aging Sci· July 2025

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Multi-Locus Pro-Dopaminergic Restoration of Reward Brain Circuitry in Reward Deficiency Rescinds Mono-Pharmaceutical Targeting.
Kenneth Blum, Kavya Mohankumar, Debasis Bagchi, Kai Uwe Lewandrowski, Alireza Sharafshah, Alexander Pl Lewandrowski

Neurology (ECronicon)· July 2025

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Exercise Leads to Brain Glucose Metabolism Activation, Increased Dopamine D1 Receptor Levels and is Negatively Correlated with Social Behavior.
Michael Bobick, Colin Hanna, John Tyler, Patrick Mohr, Huy Lu, Kai-Uwe Lewandrowski

J Integr Neurosci· June 2025

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Exploring dopamine as the master regulator of brain circuitry and mental health genome.
Kenneth Blum, Eric R Braverman, Alireza Sharafshah, Igor Elman, Kai-Uwe Lewandrowski, Alexander P L Lewandrowski

Gene Protein Dis· June 2025

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Dopaminergic Homeostatic Therapy (DHT) as a Putative Anti-Addiction Seeking Intervention and Early Identification of Genetic Preaddiction with Genetic Addiction Risk Severity (GARS) Screening.
Kai-Uwe Lewandrowski, Abdalla Bowirrat, Albert Pinhasov, Alireza Sharafshah, Mark S Gold, Alexander Pl Lewandrowski

Acta Sci Neurol· April 2025

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Personalized Repetitive Transcranial Magnetic Stimulation (PrTMS) Coupled with Transcranial Photobiomodulation (tPBM) For Co-Occurring Traumatic Brain Injury (TBI) and Post-Traumatic Stress Disorder (PTSD).
Shaurya Mahajan, Anushka Bodahanapati, Aarush Katta, Eda Aydemir, Alexandra Mendoza, Kai-Uwe Lewandrowski

Acta Sci Neurol· March 2025

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