Publications by authors named "Kam Sprott"

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INSIGHT: A Phase III Trial of Ripretinib Versus Sunitinib in Patients with Advanced GIST with KIT Exon 11 and Exon 17/18 Mutations Who Were Previously Treated with Imatinib.
Carolina Larrain, Tracey Pu, Paulina Cox, Kam Sprott, Andrew M Blakely

Ann Surg Oncol· May 2025

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The INSIGHT study: a randomized, Phase III study of ripretinib versus sunitinib for advanced gastrointestinal stromal tumor with exon 11 + 17/18 mutations.
Suzanne George, Jean-Yves Blay, Ping Chi, Robin L Jones, César Serrano, Kam Sprott

Future Oncol· October 2024

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Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial.
Michael C Heinrich, Robin L Jones, Suzanne George, Hans Gelderblom, Patrick Schöffski, Kam Sprott

Nat Med· February 2024

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Characterization and Validation of Antibodies for Immunohistochemical Staining of the Chemokine CXCL12.
Simon P Fricker, Kam Sprott, Melanie Spyra, Philipp Uhlig, Nicole Lange

J Histochem Cytochem· April 2019

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DNA repair biomarkers XPF and phospho-MAPKAP kinase 2 correlate with clinical outcome in advanced head and neck cancer.
Tanguy Y Seiwert, XiaoZhe Wang, Jana Heitmann, Vivian Villegas-Bergazzi, Kam Sprott

PLoS One· November 2015

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Microfluidics and circulating tumor cells.
Yi Dong, Alison M Skelley, Keith D Merdek, Kam M Sprott, Chunsheng Jiang

J Mol Diagn· March 2013

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Utilization of fluorescence in situ hybridization with cytokeratin discriminators in TOP2A assessment of chemotherapy-treated patients with breast cancer.
William E Pierceall, Kam M Sprott, Tuomas Heikkinen, Paivi Heikkila, Lakshmi Alaparthi

Hum Pathol· September 2012

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Strategies for H-score normalization of preanalytical technical variables with potential utility to immunohistochemical-based biomarker quantitation in therapeutic response diagnostics.
William E Pierceall, Michele Wolfe, Jessica Suschak, Hua Chang, Yan Chen, Kam M Sprott

Anal Cell Pathol (Amst)· October 2011

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DNA repair protein biomarkers associated with time to recurrence in triple-negative breast cancer.
Brian M Alexander, Kam Sprott, D Allan Farrow, XiaoZhe Wang, Alan D D'Andrea

Clin Cancer Res· December 2010

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Akt-RSK-S6 kinase signaling networks activated by oncogenic receptor tyrosine kinases.
Albrecht Moritz, Yu Li, Ailan Guo, Judit Villén, Yi Wang, Kam Sprott

Sci Signal· August 2010

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Phosphorylation of the tumor suppressor CYLD by the breast cancer oncogene IKKepsilon promotes cell transformation.
Jessica E Hutti, Rhine R Shen, Derek W Abbott, Alicia Y Zhou, Kam M Sprott

Mol Cell· May 2009

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Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis.
Joseph E Aslan, Huihong You, Danielle M Williamson, Jessica Endig, Robert T Youker, Kam Sprott

Mol Cell· May 2009

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Profiling of UV-induced ATM/ATR signaling pathways.
Matthew P Stokes, John Rush, Joan Macneill, Jian Min Ren, Kam Sprott

Proc Natl Acad Sci U S A· December 2007

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Decreased activity and enhanced nuclear export of CCAAT-enhancer-binding protein beta during inhibition of adipogenesis by ceramide.
Kam M Sprott, Michael J Chumley, Janean M Hanson, Rick T Dobrowsky

Biochem J· July 2002

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