Publications by authors named "Kangyu Lin"

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Phase 1/2 trial of encorafenib, cetuximab, and nivolumab in microsatellite stable BRAF metastatic colorectal cancer.
Van K Morris, Christine M Parseghian, Vahid Bahrambeigi, Nourhan Abdelfattah, Lianchun Xiao, Kangyu Lin

Cancer Cell· November 2025

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Time Dependency for Human Papillomavirus Circulating Tumor DNA Detection after Chemoradiation as a Prognostic Biomarker for Localized Anal Cancer.
Van K Morris, Weihong Xiao, Kangyu Lin, Chi Wut Wong, Michael T Wotman

Clin Cancer Res· June 2025

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Phase II Trial of Atezolizumab and Bevacizumab for Treatment of HPV-Positive Unresectable or Metastatic Squamous Cell Carcinoma of the Anal Canal.
Van K Morris, Suyu Liu, Kangyu Lin, Haifeng Zhu, Seema Prasad

Clin Cancer Res· May 2025

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Results of the Phase I/II Study and Preliminary B-cell Gene Signature of Combined Inhibition of Glutamine Metabolism and EGFR in Colorectal Cancer.
Kristen K Ciombor, Seong-Woo Bae, Jennifer G Whisenant, Gregory D Ayers, Quanhu Sheng, Kangyu Lin, Jordan Berlin

Clin Cancer Res· April 2025

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Clinicopathologic Features Associated with Survival for Immune Checkpoint Blockade in Patients with Metastatic Anal Cancer.
Arjun S Peddireddy, Ryan Huey, Robert A Wolff, Kangyu Lin, Jocelyn Mitchell

Cancers (Basel)· March 2025

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The Clinical Utility of a Next-Generation Sequencing-Based Approach to Detecting Circulating HPV DNA in Patients with Advanced Anal Cancer.
Deepak Bhamidipati, Jay R Johnson, Kangyu Lin, Helene Pelicano, Cathy Eng

Cancers (Basel)· January 2025

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Adaptive Plasticity Tumor Cells Modulate MAPK-Targeting Therapy Response in Colorectal Cancer.
Oscar E Villarreal, Yixin Xu, Ha Tran, Annette Machado, Dionne Prescod, Kangyu Lin

bioRxiv· January 2025

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Identification of Colorectal Cancer Cell Stemness from Single-Cell RNA Sequencing.
Kangyu Lin, Saikat Chowdhury, Mohammad A Zeineddine, Fadl A Zeineddine, Nicholas J Hornstein

Mol Cancer Res· April 2024

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Oncogenic KRAS Drives Lipofibrogenesis to Promote Angiogenesis and Colon Cancer Progression.
Wen-Hao Hsu, Kyle A LaBella, Yiyun Lin, Ping Xu, Rumi Lee, Kangyu Lin

Cancer Discov· December 2023

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CRISPR-Cas9-based functional interrogation of unconventional translatome reveals human cancer dependency on cryptic non-canonical open reading frames.
Caishang Zheng, Yanjun Wei, Peng Zhang, Kangyu Lin, Dandan He, Hye Rin Lindsay Lee

Nat Struct Mol Biol· December 2023

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Transcriptional Profiling and Consensus Molecular Subtype Assignment to Understand Response and Resistance to Anti-Epidermal Growth Factor Receptor Therapy in Colorectal Cancer.
Saikat Chowdhury, Ria Gupta, Joshua Millstein, Kangyu Lin, Valsala Haridas

JCO Precis Oncol· July 2023

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CRISPR/Cas9 screen uncovers functional translation of cryptic lncRNA-encoded open reading frames in human cancer.
Caishang Zheng, Yanjun Wei, Peng Zhang, Longyong Xu, Zhenzhen Zhang, Kangyu Lin

J Clin Invest· March 2023

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Implications of Intratumor Heterogeneity on Consensus Molecular Subtype (CMS) in Colorectal Cancer.
Saikat Chowdhury, Matan Hofree, Kangyu Lin, Dipen Maru, Scott Kopetz

Cancers (Basel)· September 2021

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Aberrant Activation of β-Catenin Signaling Drives Glioma Tumorigenesis via USP1-Mediated Stabilization of EZH2.
Li Ma, Kangyu Lin, Guoqiang Chang, Yiwen Chen, Chen Yue

Cancer Res· January 2019

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Gli1-induced deubiquitinase USP48 aids glioblastoma tumorigenesis by stabilizing Gli1.
Aidong Zhou, Kangyu Lin, Sicong Zhang, Li Ma, Jianfei Xue

EMBO Rep· August 2017

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mA Demethylase ALKBH5 Maintains Tumorigenicity of Glioblastoma Stem-like Cells by Sustaining FOXM1 Expression and Cell Proliferation Program.
Sicong Zhang, Boxuan Simen Zhao, Aidong Zhou, Kangyu Lin, Shaoping Zheng

Cancer Cell· April 2017

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Nuclear GSK3β promotes tumorigenesis by phosphorylating KDM1A and inducing its deubiquitylation by USP22.
Aidong Zhou, Kangyu Lin, Sicong Zhang, Yaohui Chen, Nu Zhang

Nat Cell Biol· September 2016

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miR-182-5p Induced by STAT3 Activation Promotes Glioma Tumorigenesis.
Jianfei Xue, Aidong Zhou, Yamei Wu, Saint-Aaron Morris, Kangyu Lin

Cancer Res· July 2016

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Wnt-induced deubiquitination FoxM1 ensures nucleus β-catenin transactivation.
Yaohui Chen, Yu Li, Jianfei Xue, Aihua Gong, Guanzhen Yu, Kangyu Lin

EMBO J· March 2016

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Synergism between the mTOR inhibitor rapamycin and FAK down-regulation in the treatment of acute lymphoblastic leukemia.
Pei-Jie Shi, Lu-Hong Xu, Kang-Yu Lin, Wen-jun Weng, Jian-Pei Fang

J Hematol Oncol· February 2016

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Tumour suppressor TRIM33 targets nuclear β-catenin degradation.
Jianfei Xue, Yaohui Chen, Yamei Wu, Zhongyong Wang, Aidong Zhou, Kangyu Lin

Nat Commun· February 2015

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MIR125B1 represses the degradation of the PML-RARA oncoprotein by an autophagy-lysosomal pathway in acute promyelocytic leukemia.
Cheng-Wu Zeng, Zhen-Hua Chen, Xing-Ju Zhang, Bo-Wei Han, Kang-Yu Lin

Autophagy· October 2014

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A distinct set of long non-coding RNAs in childhood MLL-rearranged acute lymphoblastic leukemia: biology and epigenetic target.
Ke Fang, Bo-Wei Han, Zhen-Hua Chen, Kang-Yu Lin, Cheng-Wu Zeng

Hum Mol Genet· June 2014

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miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression.
Fang-Ting Duan, Feng Qian, Ke Fang, Kang-Yu Lin, Wen-Tao Wang

Mol Cancer· December 2013

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Diverse functions of miR-125 family in different cell contexts.
Yu-Meng Sun, Kang-Yu Lin, Yue-Qin Chen

J Hematol Oncol· January 2013

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