Publications by authors named "Karin Lin"

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Chronic integrated stress response causes dysregulated cholesterol synthesis in white matter disease.
Karin Lin, Nina Ly, Rejani B Kunjamma, Ngoc Vu, Bryan King, Caitlin F Connelly

JCI Insight· August 2025

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Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Alexandra Litvinchuk, Jung H Suh, Jing L Guo, Karin Lin, Sonnet S Davis, Javier Remolina Serrano

Neuron· June 2024

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Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Alexandra Litvinchuk, Jung H Suh, Jing L Guo, Karin Lin, Sonnet S Davis, Javier Remolina Serrano

Neuron· February 2024

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Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Dan Xia, Steve Lianoglou, Thomas Sandmann, Meredith Calvert, Jung H Suh, Chia-Ching Lin, Karin Lin, Selina Hummel

Mol Neurodegener· June 2022

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MHC class I H2-Kb negatively regulates neural progenitor cell proliferation by inhibiting FGFR signaling.
Karin Lin, Gregor Bieri, Geraldine Gontier, Sören Müller, Lucas K Smith

PLoS Biol· June 2021

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Alzheimer's-associated PLCγ2 is a signaling node required for both TREM2 function and the inflammatory response in human microglia.
Benjamin J Andreone, Laralynne Przybyla, Ceyda Llapashtica, Anil Rana, Sonnet S Davis, Karin Lin

Nat Neurosci· August 2020

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The aged hematopoietic system promotes hippocampal-dependent cognitive decline.
Lucas K Smith, Evgenia Verovskaya, Gregor Bieri, Alana M Horowitz, Saskia N I von Ungern-Sternberg, Karin Lin

Aging Cell· August 2020

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TREM2 Regulates Microglial Cholesterol Metabolism upon Chronic Phagocytic Challenge.
Alicia A Nugent, Karin Lin, Bettina van Lengerich, Steve Lianoglou, Laralynne Przybyla, Melina Lenser

Neuron· March 2020

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Fat Chance for Neural Stem Cells in Alzheimer's Disease.
Geraldine Gontier, Karin Lin, Saul A Villeda

Cell Stem Cell· October 2015

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β2-microglobulin is a systemic pro-aging factor that impairs cognitive function and neurogenesis.
Lucas K Smith, Yingbo He, Jeong-Soo Park, Gregor Bieri, Cedric E Snethlage, Karin Lin, Jacqueline L Grant

Nat Med· August 2015

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Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice.
Saul A Villeda, Kristopher E Plambeck, Jinte Middeldorp, Joseph M Castellano, Kira I Mosher, Karin Lin

Nat Med· June 2014

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