Publications by authors named "Karl Clark"

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Mucopolysaccharidosis Type IIIA Presenting as Hypertrophic Cardiomyopathy.
Filippo Pinto E Vairo, Jeffrey B Geske, Ravinder J Singh, Roy B Dyer, Konstantinos C Siontis, Karl J Clark

Circ Heart Fail· July 2025

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A Novel Zebrafish Model for Assessing In Vivo Delivery of Morpholino Oligomers.
Joseph Kim, Karl Clark, Carrie Barton, Robert Tanguay, Hong Moulton

Methods Mol Biol· July 2025

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Lineage labeling with zebrafish hand2 Cre and CreERT2 recombinase CRISPR knock-ins.
Zhitao Ming, Fang Liu, Hannah R Moran, Robert L Lalonde, Megan Adams, Karl J Clark

Dev Dyn· March 2025

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Lineage labeling with zebrafish Cre and CreERT2 recombinase CRISPR knock-ins.
Zhitao Ming, Fang Liu, Hannah R Moran, Robert L Lalonde, Megan Adams, Karl J Clark

bioRxiv· December 2024

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Unconstrained Precision Mitochondrial Genome Editing with αDdCBEs.
Santiago R Castillo, Brandon W Simone, Karl J Clark, Patricia Devaux, Stephen C Ekker

Hum Gene Ther· October 2024

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Engineered transcription activator-like effector dimer proteins confer DNA loop-dependent gene repression comparable to Lac repressor.
Nicole A Becker, Justin P Peters, Elizabeth Lewis, Camden L Daby, Karl Clark

Nucleic Acids Res· September 2024

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Unconstrained Precision Mitochondrial Genome Editing with αDdCBEs.
Santiago R Castillo, Brandon W Simone, Karl J Clark, Patricia Devaux, Stephen C Ekker

bioRxiv· May 2024

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Key HPI axis receptors facilitate light adaptive behavior in larval zebrafish.
Han B Lee, Soaleha Shams, Viet Ha Dang Thi, Grace E Boyum, Rodsy Modhurima, Karl J Clark

Sci Rep· April 2024

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Nuclear Abnormalities in p.(Glu2Lys) Variant Segregating with -Associated Cardiocutaneous Progeria Syndrome.
Matheus V M B Wilke, Myra Wick, Tanya L Schwab, Rodrigo Tzovenos Starosta, Karl J Clark

Genes (Basel)· January 2024

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The canonical HPA axis facilitates and maintains light adaptive behavior.
Han Lee, Soaleha Shams, Viet Ha Dang Thi, Grace Boyum, Rodsy Modhurima, Karl Clark

Res Sq· September 2023

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Bi-allelic variants in HMGCR cause an autosomal-recessive progressive limb-girdle muscular dystrophy.
Joel A Morales-Rosado, Tanya L Schwab, Sarah K Macklin-Mantia, A Reghan Foley, Filippo Pinto E Vairo, Karl J Clark

Am J Hum Genet· June 2023

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Bi-allelic variants in INTS11 are associated with a complex neurological disorder.
Burak Tepe, Erica L Macke, Marcello Niceta, Monika Weisz Hubshman, Oguz Kanca, Karl Clark

Am J Hum Genet· May 2023

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Mitochondrial Base Editing: Recent Advances towards Therapeutic Opportunities.
Bibekananda Kar, Santiago R Castillo, Ankit Sabharwal, Karl J Clark, Stephen C Ekker

Int J Mol Sci· March 2023

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Impact of integrated translational research on clinical exome sequencing.
Eric W Klee, Margot A Cousin, Filippo Pinto E Vairo, Joel A Morales-Rosado, Erica L Macke, Karl J Clark

Genet Med· February 2023

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A phenotype-based forward genetic screen identifies as a sick sinus syndrome gene.
Yonghe Ding, Di Lang, Jianhua Yan, Haisong Bu, Hongsong Li, Karl J Clark

Elife· October 2022

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A Primer Genetic Toolkit for Exploring Mitochondrial Biology and Disease Using Zebrafish.
Ankit Sabharwal, Jarryd M Campbell, Tanya L Schwab, Zachary WareJoncas, Mark D Wishman, Karl J Clark

Genes (Basel)· July 2022

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An optimized FusX assembly-based technique to introduce mitochondrial TC-to-TT variations in human cell lines.
Bibekananda Kar, Ankit Sabharwal, Santiago Restrepo-Castillo, Brandon W Simone, Karl J Clark

STAR Protoc· June 2022

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Cre/ regulated conditional rescue and inactivation with zebrafish UFlip alleles generated by CRISPR-Cas9 targeted integration.
Fang Liu, Sekhar Kambakam, Maira P Almeida, Zhitao Ming, Jordan M Welker, Karl J Clark

Elife· June 2022

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Chimeric RNA: DNA TracrRNA Improves Homology-Directed Repair and .
Brandon W Simone, Han B Lee, Camden L Daby, Hirotaka Ata, Santiago Restrepo-Castillo, Karl J Clark

CRISPR J· February 2022

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The FusX TALE Base Editor (FusXTBE) for Rapid Mitochondrial DNA Programming of Human Cells and Zebrafish Disease Models .
Ankit Sabharwal, Bibekananda Kar, Santiago Restrepo-Castillo, Shannon R Holmberg, Neal D Mathew, Karl J Clark

CRISPR J· December 2021

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Designed architectural proteins that tune DNA looping in bacteria.
David H Tse, Nicole A Becker, Robert T Young, Wilma K Olson, Justin P Peters, Karl J Clark

Nucleic Acids Res· October 2021

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GeneWeld: Efficient Targeted Integration Directed by Short Homology in Zebrafish.
Jordan M Welker, Wesley A Wierson, Maira P Almeida, Carla M Mann, Melanie E Torrie, Karl J Clark

Bio Protoc· July 2021

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The NIH Somatic Cell Genome Editing program.
Krishanu Saha, Erik J Sontheimer, P J Brooks, Melinda R Dwinell, Charles A Gersbach, Karl J Clark

Nature· April 2021

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Endogenous zebrafish proneural Cre drivers generated by CRISPR/Cas9 short homology directed targeted integration.
Maira P Almeida, Jordan M Welker, Sahiba Siddiqui, Jon Luiken, Stephen C Ekker, Karl J Clark

Sci Rep· January 2021

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