Publications by authors named "Karl Desch"

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Multipopulation GWAS for venous thromboembolism identifies novel loci followed by experimental validation in zebrafish.
Brooke N Wolford, Queena Yakun Zhao, Kuan-Han H Wu, Xinge Yu, Catherine E Richter, Karl C Desch

Blood Adv· October 2025

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Comparative microfluidic and enzymatic analyses reveal multifaceted snake venom resistance and novel VWF behavior in the opossum Monodelphis domestica.
Matthew L Holding, Dante Disharoon, Laura M Haynes, Bipin Chakravarthy Paruchuri, M Hao Hao Pontius, Karl C Desch

PLoS One· September 2025

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Not dead yet: GWAS insights into a common bleeding disorder.
Karl C Desch

Blood· August 2025

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Genome-wide association and linkage analysis of histidine-rich glycoprotein identifies common variants associated with plasma histidine-rich glycoprotein concentrations.
Mary I Underwood, Ayse Bilge Ozel, Tanay Deepak, Beth McGee, Dave Siemieniak, Karl C Desch

Res Pract Thromb Haemost· July 2025

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Identification of multiple novel procoagulant plasma ligands for stabilin-2.
Mary Underwood, Felipe Da Veiga Leprevost, Venkatesha Basrur, Alexey I Nesvizhskii, Orla Rawley, Karl Desch

J Thromb Haemost· May 2025

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Species-specific, multifaceted venom resistance in reveals novel physiological behavior of von Willebrand Factor under flow.
Matthew Holding, Dante Disharoon, Laura Haynes, Bipin Chakravarthy Paruchuri, M Hao Hao Pontius, Karl Desch

bioRxiv· May 2025

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Neonatal Encephalopathy: Novel Phenotypes and Genotypes Identified by Genome Sequencing.
Anastasia Ambrose, Vanda McNiven, Diane Wilson, Aleksandra Tempes, Mary Underwood, Karl Desch

Neurol Genet· February 2025

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Venous thromboembolic disease genetics: from variants to function.
Mary Underwood, Christopher Bidlack, Karl C Desch

J Thromb Haemost· September 2024

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A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels.
Paul S de Vries, Paula Reventun, Michael R Brown, Adam S Heath, Jennifer E Huffman, Karl C Desch

Blood· May 2024

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LDL vs HDL: a sticky situation.
Karl Desch

Blood· September 2023

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Antithrombin, Protein C, and Protein S: Genome and Transcriptome-Wide Association Studies Identify 7 Novel Loci Regulating Plasma Levels.
Yuekai Ji, Gerard Temprano-Sagrera, Lori A Holle, Allison Bebo, Jennifer A Brody, Karl C Desch

Arterioscler Thromb Vasc Biol· July 2023

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Illustrated State-of-the-Art Capsules of the ISTH 2023 Congress.
Susan R Kahn, Donald M Arnold, Caterina Casari, Karl C Desch, Katrien M J Devreese

Res Pract Thromb Haemost· May 2023

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Increased soluble urokinase plasminogen activator levels modulate monocyte function to promote atherosclerosis.
George Hindy, Daniel J Tyrrell, Alexi Vasbinder, Changli Wei, Feriel Presswalla, Karl C Desch

J Clin Invest· December 2022

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FGL1 as a modulator of plasma D-dimer levels: Exome-wide marker analysis of plasma tPA, PAI-1, and D-dimer.
Florian Thibord, Ci Song, Jack Pattee, Benjamin A T Rodriguez, Ming-Huei Chen, Karl C Desch

J Thromb Haemost· August 2021

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The Endoplasmic Reticulum Cargo Receptor SURF4 Facilitates Efficient Erythropoietin Secretion.
Zesen Lin, Richard King, Vi Tang, Greggory Myers, Ginette Balbin-Cuesta, Karl Desch

Mol Cell Biol· November 2020

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Of Pea Plants and Platelets.
Karl C Desch

Circ Res· October 2020

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Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease.
Karl C Desch, Ayse B Ozel, Matt Halvorsen, Paula M Jacobi, Krista Golden

Blood· July 2020

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Markers of Endothelial Dysfunction and Cytokines in High-Risk Pediatric Patients with Severe Sepsis.
Erin F Carlton, Walker M McHugh, Kelli McDonough, Julie Sturza, Karl Desch

Am J Respir Crit Care Med· February 2020

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Genome-wide linkage analysis and whole-exome sequencing identifies an ITGA2B mutation in a family with thrombocytopenia.
Rami Khoriaty, Ayse B Ozel, Shweta Ramdas, Charles Ross, Karl Desch

Br J Haematol· August 2019

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Tuning the Thromboinflammatory Response to Venous Flow Interruption by the Ectonucleotidase CD39.
Anuli C Anyanwu, Yogendra Kanthi, Keigo Fukase, Hui Liao, Tekashi Mimura, Karl C Desch

Arterioscler Thromb Vasc Biol· April 2019

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α-galactosidase A deficiency promotes von Willebrand factor secretion in models of Fabry disease.
Justin J Kang, Nayiri M Kaissarian, Karl C Desch, Robert J Kelly, Liming Shu

Kidney Int· January 2019

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Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.
Maria Sabater-Lleal, Jennifer E Huffman, Paul S de Vries, Jonathan Marten, Michael A Mastrangelo, Karl C Desch

Circulation· January 2019

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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
Symen Ligthart, Ahmad Vaez, Urmo Võsa, Maria G Stathopoulou, Paul S de Vries, Karl C Desch

Am J Hum Genet· November 2018

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Regulation of plasma von Willebrand factor.
Karl C Desch

F1000Res· January 2018

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Genetic variants in as well as smoking are major determinants of plasma ADAMTS13 levels.
Qianyi Ma, Paula M Jacobi, Brian T Emmer, Colin A Kretz, Ayse Bilge Ozel, Karl C Desch

Blood Adv· June 2017

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